[Expressed in many cells by human PLA2G2A Gene (PLA2 Type II Family), identical membrane-bound and secreted forms of 144-aa 16-kDa (precursor) Phospholipase A2 Group IIA catalyze calcium-dependent hydrolysis of sn-2 fatty acid acyl ester bonds in 3-sn-phosphoglycerides, releasing free fatty acids and lysophospholipids. Thought to regulate biomembrane phospholipid metabolism and eicosanoid biosynthesis, PLA2G2A is likely involved in a variety of cellular processes, including production of precursors for inflammatory reactions. (NCI) ( NCI )]
UMLS (NCI) C0536678 - Amino Acid, Peptide, or Protein
- Enzyme