BCR Downstream Signaling 1
[BCR Downstream Signaling 1, encoded by BRDG1 gene, functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling. This protein is directly phosphorylated by Tec in vitro where it participates in a positive feedback loop, increasing Tec activity. A mouse ortholog, stem cell adaptor protein 1, shares 83% identity with its human counterpart. It has a proline-rich region, a pleckstrin homology domain and SH2 domain. (From LocusLink, Swiss_Prot and NCI) ( NCI )]
UMLS (NCI) C1332405BRDG1
Docking protein BRDG1
STAP-1
Docking protein BRDG1
STAP-1
- Amino Acid, Peptide, or Protein
- Biologically Active Substance
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