BCAR3

1. [Encoded by human BCAR3 Gene, the 92.6 kD 825-amino acid BCAR3 Protein contains a putative SH2 domain, a hallmark of tyrosine kinase signaling molecules, and sequences homologous to CDC48 (Yeast). Abundant expression is seen in heart, placenta, skeletal muscle, spleen, prostate, testis, ovary, small intestine, colon, fetal kidney, and several cancer cell lines, but not in nonmalignant breast tissue. NSP2 induces anti-estrogen resistance in estrogen-dependent breast tumors. (from SWISS-PROT, OMIM, and NCI) ( NCI )]
   UMLS (NCI) C1309026
   
   Breast Cancer Anti-Estrogen Resistance 3
   Breast Cancer Anti-Estrogen Resistance 3 Protein
   Novel SH2-Containing Protein 2
    

   Amino Acid, Peptide, or Protein

   Biologically Active Substance

2. [This gene plays a role in cell cycle regulation and tumorigenesis. ( NCI )]
   UMLS (NCI) C1332386
   
   BCAR3 Gene
   Breast Cancer Anti-Estrogen Resistance 3 Gene
    

   Gene or Genome