B Prime Alpha Regulatory Subunit

[Ubiquitously expressed as 3 isoforms by human PPP2R5C Gene (PP2A Subunit B Family), Protein Phosphatase 2 Regulatory Subunit B Gamma is a regulatory subunit of PP2A. Nuclear Gamma-3 is serine phosphorylated, while nuclear Gamma-1 is not. A major Ser/Thr phosphatase implicated in negative control of cell growth and division, PP2A core enzyme consists of a 36-kDa catalytic C subunit and a constant 65-kDa regulatory/structural A subunit that interact with either a B regulatory subunit or with cell signaling molecules, that likely modulate substrate selectivity, catalytic activity, and subcellular localization, yielding the trimeric holoenzyme. Different subunit isoforms can generate many forms of PP2A, which may differ in substrate specificity, subcellular localization, or tissue specific expression. (NCI) ( NCI )]

UMLS (NCI) C1335546

B56G
PP2A B Subunit B Prime Gamma
PP2A B Subunit B56 Gamma
PP2A B Subunit PR61 Gamma
PP2A B Subunit R5 Gamma
PPP2R5C
Protein Phosphatase 2 Regulatory Subunit B Gamma
Protein Phosphatase 2A Regulatory Subunit B56 Gamma
Serine/Threonine Protein Phosphatase 2A 56 kDa Regulatory Subunit Gamma

Amino Acid, Peptide, or Protein
Biologically Active Substance

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