[The hydrochloride salt form of lomefloxacin, a synthetic broad-spectrum fluoroquinolone with antibacterial activity. Lomefloxacin hydrochloride inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during bacterial replication, resulting in cell growth inhibition and eventually cell lysis. ( NCI )]
UMLS (NCI) C0770927Lomefloxacin Hydrochloride
LOMEFLOXACIN HYDROCHLORIDE PREPARATION
- Organic Chemical
- Pharmacologic Substance
Relation/PAR: Lomefloxacin
Relation/CHD: LOMEFLOXACIN HYDROCHLORIDE 400 MG