- 1. TAF (T cell activating factor)
- [ ] (UMLS (CSP) C0598895) =Immunologic Factor ;
| - 13. TAF2E
- [Encoded by human TAF6 Gene (TAF2E Family), 677-aa 73-kDa nuclear TBP-Associated Factor 6, one of the smaller TFIID subunits, binds tightly to TAF1 (the largest subunit of TFIID) to TBP, and directly to TAFII40. Four isoforms have been identified; one isoform precludes binding of another TFIID subunit, reducing transcription and initiating apoptotic signals. TFIID is composed of TBP and many evolutionarily conserved TAFs, which participate in basal transcription, serve as coactivators, and function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. Multimeric protein complex TFIID binds to the core promoter to position polymerase, serves as scaffold for assembly of the transcription complex, and acts as a channel for regulatory signals. (NCI) ( NCI )] (UMLS (NCI) C0380088) =Amino Acid, Peptide, or Protein; Biologically Active Substance
|
- 2. TAF1
- [This gene is involved in transcriptional initiation, cell cycle progression and ubiquitination. ( NCI )] (UMLS (NCI) C1336564) TAF1 Gene;
TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa Gene;
=Gene or Genome ;
| - 14. TAF2F
- [Encoded by human TAF7 Gene (TAF2F Family), ubiquitous 349-aa 40-kDa nuclear TBP-Associated Factor F is a component of TFIID complex (with or without TAFII30) that binds class II promoter TATA boxes and recruits RNA polymerase II and other factors. TAF7 interacts with TAFII250, TAFII100, TAFII28, TAFII20, TAFII18, and multiple transcription activators. TFIID is composed of TBP and many evolutionarily conserved TAFs, which participate in basal transcription, serve as coactivators, and function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. Multimeric protein complex TFIID binds to the core promoter to position polymerase, serves as scaffold for assembly of the transcription complex, and acts as a channel for regulatory signals. (NCI) ( NCI )] (UMLS (NCI) C0528246) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 3. TAF10
- [This gene is involved in transcriptional initiation, cell cycle progression and differentiation. ( NCI )] (UMLS (NCI) C1336560) TAF10 Gene;
TAF10 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 30kDa Gene;
=Gene or Genome ;
| - 15. TAF2Q
- [Expressed specifically in male germ cells (testis) by human TAF7L Gene, TBP-Associated Factor 50kDa is a component of TFIID, composed of TBP and many evolutionarily conserved TAFs, which participate in basal transcription, serve as coactivators, and function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. Multimeric protein complex TFIID binds to the core promoter to position polymerase, serves as scaffold for assembly of the transcription complex, and acts as a channel for regulatory signals. (NCI) ( NCI )] (UMLS (NCI) C1336587) TAF7L;
TAF7-Like RNA Polymerase II;
TATA Box Binding Protein-Associated Factor 50kDa;
TATA Box Binding Protein-Associated Factor RNA Polymerase II Q;
TBP-Associated Factor 50kDa;
TBP-Associated Factor RNA Polymerase II Q =Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 4. TAF11
- [This gene plays a role in transcriptional initiation and signal transduction modulation. ( NCI )] (UMLS (NCI) C1336561) TAF11 Gene;
TAF11 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 28kDa Gene;
=Gene or Genome ;
◊ [Encoded by human TAF11 Gene (TAF2I Family), 211-aa 23-kDa nuclear TBP-Associated Factor 11 is a small subunit of all TFIID complexes that interacts directly with TBP, interacts with TAFII18, and interacts with TAF13 to form a heterodimer with a structure similar to the histone core structure. TBP and TAFII18 bind to distinct domains of TAF11. TFIID is composed of TBP and many evolutionarily conserved TAFs, which participate in basal transcription, serve as coactivators, and function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. Multimeric protein complex TFIID binds to the core promoter to position polymerase, serves as scaffold for assembly of the transcription complex, and acts as a channel for regulatory signals. (NCI) ( NCI )] (UMLS (NCI) C1336580) TAF11 RNA Polymerase II; TAFII28; TATA Box Binding Protein-Associated Factor RNA Polymerase II I 28kD; TBP-Associated Factor 11; TBP-Associated Factor 28kDa; TBP-Associated Factor RNA Polymerase II I 28kD; TFIID Subunit p30-Beta; Transcription Initiation Factor TFIID 28 kD Subunit Amino Acid, Peptide, or Protein; Biologically Active Substance | - 16. TAF3
- [This gene plays a role in transcriptional initiation and promoter recognition. ( NCI )] (UMLS (NCI) C1336566) TAF3 Gene;
TAF3 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 140kDa Gene;
=Gene or Genome ;
|
- 5. TAF12
- [Ubiquitously expressed as alternative initiation isoforms by human TAF12 Gene (TAF2J Family), nuclear (18-kDa precursor) TBP-Associated Factor 15 kDa and 20 kDa, similar to Histones H2B and H3, are components of the TFIID complex essential for regulation of transcription. A component of the PCAF complex and the STAGA transcription coactivator-HAT complex, TAF12 interacts directly with TBP and TAF11, as well as with TAFII20 and TAFII30. TFIID is composed of TBP and many TAF proteins. Control of transcription by the RNA polymerase II basal transcription machinery complex is modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to transcription start sites. Some modulators interact directly with the basal complex; others may bridge transactivators to the basal factors. Different TAFs may mediate distinct transcriptional activators. (NCI) ( NCI )] (UMLS (NCI) C1173190) TAF12 RNA Polymerase II;
TAF2J;
TAFII20;
TATA Box Binding Protein-Associated Factor 20kDa;
TATA Box Binding Protein-Associated Factor RNA Polymerase II J 20kD;
TBP-Associated Factor 20 kDa;
TBP-Associated Factor RNA Polymerase II J 20kD;
Transcription Initiation Factor TFIID 20 kDa Subunit =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 17. TAF4
- [This gene plays a role in CREB mediated transcriptional initiation. ( NCI )] (UMLS (NCI) C1336567) TAF4 Gene;
TAF4 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 135kDa Gene;
=Gene or Genome ;
|
- 6. TAF12
- [This gene is involved in transcriptional initiation. ( NCI )] (UMLS (NCI) C1336562) TAF12 Gene;
TAF12 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 20kDa Gene;
=Gene or Genome ;
◊ [Ubiquitously expressed as alternative initiation isoforms by human TAF12 Gene (TAF2J Family), nuclear (18-kDa precursor) TBP-Associated Factor 15 kDa and 20 kDa, similar to Histones H2B and H3, are components of the TFIID complex essential for regulation of transcription. A component of the PCAF complex and the STAGA transcription coactivator-HAT complex, TAF12 interacts directly with TBP and TAF11, as well as with TAFII20 and TAFII30. TFIID is composed of TBP and many TAF proteins. Control of transcription by the RNA polymerase II basal transcription machinery complex is modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to transcription start sites. Some modulators interact directly with the basal complex; others may bridge transactivators to the basal factors. Different TAFs may mediate distinct transcriptional activators. (NCI) ( NCI )] (UMLS (NCI) C1336583) TAF12 RNA Polymerase II; TAF2J; TAFII15; TATA Box Binding Protein-Associated Factor 15 kDa; TBP-Associated Factor 15 kDa; Transcription Initiation Factor TFIID 15 kDa Subunit Amino Acid, Peptide, or Protein; Biologically Active Substance | - 18. TAF5
- [This gene plays a role in transcriptional initiation and core promoter-specific function. ( NCI )] (UMLS (NCI) C1336568) TAF5 Gene;
TAF5 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 100kDa Gene;
=Gene or Genome ;
|
- 7. TAF13
- [Encoded by human TAF13 Gene (TAF2K Family), 124-aa 14-kDa nuclear TBP-Associated Factor 13 is a small subunit associated with a subset of TFIID complexes (TFIID Beta-specific). TAF13 interacts with TBP and with strongly TAF10 and TAF11; TAF10 and TAF11 binding involves distinct TAFII18 domains. TFIID is composed of TBP and many evolutionarily conserved TAFs, which participate in basal transcription, serve as coactivators, and function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. Multimeric protein complex TFIID binds to the core promoter to position polymerase, serves as scaffold for assembly of the transcription complex, and acts as a channel for regulatory signals. (NCI) ( NCI )] (UMLS (NCI) C0756346) TAF13 RNA Polymerase II;
TAFII18;
TATA Box Binding Protein-Associated Factor 18kDa;
TBP-Associated Factor 13;
TBP-Associated Factor 18kDa;
Transcription Initiation Factor TFIID 18 kD Subunit =Amino Acid, Peptide, or Protein; Biologically Active Substance | - 19. TAF6
- [This gene is involved in transcriptional initiation, apoptosis regulation and signal transduction. ( NCI )] (UMLS (NCI) C1336569) TAF6 Gene;
TAF6 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 80kDa Gene;
=Gene or Genome ;
|
- 8. TAF13
- [This gene is involved in transcriptional initiation. ( NCI )] (UMLS (NCI) C1336563) TAF13 Gene;
TAF13 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 18kDa Gene;
=Gene or Genome ;
| - 20. TAF7
- [This gene plays a role in transcriptional initiation. ( NCI )] (UMLS (NCI) C1336571) TAF7 Gene;
TAF7 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 55kDa Gene;
=Gene or Genome ;
|
- 9. TAF2
- [Encoded by human TAF2 Gene, 1,199-aa TBP-Associated Factor 2 is one of the larger subunits associated with TFIID, shares 53% identity with its Drosophila homologue, and contains a stretch of 7 His residues near the C terminus. Stably associated with TAF2C1, TAF2D, and TBP as an essential cofactor for TFIID/TBP-dependent transcription from promoters containing initiator elements, TAF2B contributes to interactions that determine response of the complex to activators. TFIID is composed of TBP and many evolutionarily conserved TAFs, which participate in basal transcription, serve as coactivators, and function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. Multimeric protein complex TFIID binds to the core promoter to position polymerase, serves as scaffold for assembly of the transcription complex, and acts as a channel for regulatory signals. (NCI) ( NCI )] (UMLS (NCI) C0669417) =Amino Acid, Peptide, or Protein; Biologically Active Substance
| - 21. TAF7L
- [This gene plays a role in transcriptional initiation and has testis-specific expression. ( NCI )] (UMLS (NCI) C1420574) TAF7L Gene;
TAF7-Like RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 50kDa Gene =Gene or Genome |
- 10. TAF2
- [This gene plays a role in transcriptional initiation. ( NCI )] (UMLS (NCI) C1336565) TAF2 Gene;
TAF2 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 150kDa Gene;
=Gene or Genome ;
| - 22. TAF8
- [No info. in OMIM, PubMed or HUGO as of 12/09/2003. ( NCI )] (UMLS (NCI) C1336572) Taube Nuss Homolog (Mouse) wt Allele;
TBN;
TBN wt Allele =Gene or Genome ;
◊ [No info. in OMIM, PubMed or HUGO as of 12/09/2003. ( NCI )] (UMLS (NCI) C1336696) TAF8 RNA Polymerase II; TATA Box Binding Protein-Associated Factor 50 kD; TATA Box Binding Protein-Associated Factor RNA Polymerase II A 45-50kD; Taube Nuss Homologue; TBN; TBP-Associated Factor 50 kD; TBP-Associated Factor RNA Polymerase II A 45-50kD Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 11. TAF2C
- [Encoded by human TAF4 Gene (TAF2C Family), 1083-aa 110-kDa nuclear TBP-Associated Factor 4, containing 1 TAFH/NHR1 domain, is one of the larger subunits of the multimeric TFIID complex that mediates promoter responses to various activators and repressors. A component of the TFTC-HAT complex, TAF4 interacts with transcription factor CREB and other proteins containing glutamine-rich regions and potentiates transcriptional activation by the AF-2S of the RAR, THR and vitamin D3 receptor. TFIID is composed of TBP and many evolutionarily conserved TAFs, which participate in basal transcription, serve as coactivators, and function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. Multimeric protein complex TFIID binds to the core promoter to position polymerase, serves as scaffold for assembly of the transcription complex, and acts as a channel for regulatory signals. (NCI) ( NCI )] (UMLS (NCI) C1336585) TAF2C1;
TAF4;
TAF4 RNA Polymerase II;
TAF4A;
TAFII130;
TAFII135;
TATA Box Binding Protein-Associated Factor 135 kD;
TATA Box Binding Protein-Associated Factor RNA Polymerase II C1 130kD;
TBP-Associated Factor 135 kD;
TBP-Associated Factor 4;
TBP-Associated Factor RNA Polymerase II C1 130kD;
Transcription Initiation Factor TFIID 135 kDa Subunit =Amino Acid, Peptide, or Protein; Biologically Active Substance | - 23. TAF9
- [This gene is involved in transcriptional initiation and signal transduction. ( NCI )] (UMLS (NCI) C1336573) TAF9 Gene;
TAF9 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 32kDa Gene;
=Gene or Genome ;
|
- 12. TAF2D
- [Encoded by human TAF5 Gene, alternative 745-aa and 800-aa 87-kDa isoforms of nuclear TBP-Associated Factor 5 interact strongly with (histone H4-related) TAFII80 and (histone H3-related) TAFII31, as well as with TBP, TAFII250, TAFII28, and TAFII20. A component of the TFTC-HAT complex, TAFII100 contains 1 LisH domain and 6 WD repeats; distinct TAFII100 domains are required for interaction with TFIIFB and for incorporation into TFIID. TFIID is composed of TBP and many evolutionarily conserved TAFs, which participate in basal transcription, serve as coactivators, and function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. Multimeric protein complex TFIID binds to the core promoter to position polymerase, serves as scaffold for assembly of the transcription complex, and acts as a channel for regulatory signals. (NCI) ( NCI )] (UMLS (NCI) C0391783) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| |
home
