- 1. Mikamycin
- [A class of streptogramin-related depsipeptides isolated from the bacterium Streptomyces virginiae and other Streptomyces bacterial species. The virginiamycins consist of two major components, virginiamycin M1 and virginiamycin S1. These agents bind to and inhibit ribosome assembly, thereby preventing protein synthesis. Active against Gram-positive bacteria, these antibiotics are primarily used in veterinary practice. (NCI04) ( NCI )] (UMLS (NCI) C0042754) =Amino Acid, Peptide, or Protein; Antibiotic =cyclic peptide;
=N-((6R,9S,10R,13S,15aS,18R,22S,24aS)-22-(p-(Dimethylamino)benzyl)-6-ethyldocosahydro-10,23-dimethyl-5,8,12,15,17,21,24-heptaoxo-13-phenyl-18-(((3S)-3-quinuclidinylthio)methyl)-12H-pyrido(2,1-f)pyrrolo(2,1-l)(1,4,7,10,13,16)oxapentaazacyclononadecin-9-yl)-3-hydroxypicolinamide;
3R,4R,5E,10E,12E,14S,26R,26aS)-26-((2-(Diethylamino)ethyl)sulfonyl)-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-3-isopropyl-4,12-dimethyl-3H-21,18-nitrilo-1H,22H-pyrrolo(2,1-c)(1,8,4,19)dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone;
| - 3. Mikulicz Disease
- [A chronic, benign, and usually painless inflammatory swelling of the lacrimal and salivary glands. It is considered by some to include the glandular enlargement associated with other diseases, such as Sjogren's syndrome, sarcoidosis, lupus erythematosus, etc. ( MSH )] (UMLS (NCI) C0026103) =Disease or Syndrome =Diseases of the salivary glands;
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