- 1. (-)-Hydromorphone
- [The hydrogenated ketone of morphine, a semi-synthetic opioid with analgesic effects. Hydromorphone selectively binds the mu-opioid receptor which is linked through G-proteins. Binding stimulates the exchange of guanosine triphosphate (GTP) for guanosine diphosphate (GDP) on the G-protein complex and interacts with and inhibits adenylate cyclase located at the inner surface of the plasma membrane. This leads to a reduction in intracellular cyclic 3',5'-adenosine monophosphate (cAMP). Further, voltage-gated potassium channels are activated, thereby causing hyperpolarization and reducing neuronal excitability. In addition, the opening of voltage-gated calcium channels is inhibited, thereby leading to an inhibition of calcium entry and a reduction in the release of various neurotransmitters, including GABA, vasopressin, somatostatin, insulin and glucagons. ( NCI )] (UMLS (NCI) C0012306) =Organic Chemical; Pharmacologic Substance =[CN101] OPIOID ANALGESICS;
Morphine Derivatives =OXYMORPHONE;
HYDROMORPHONE HYDROCHLORIDE;
HYDROMORPHONE 2 MG | - 51. Hydatid Mole
- [trophoblastic hyperplasia associated with normal gestation, or molar pregnancy; characterized by the swelling of the chorionic villi and elevated human chorionic gonadotropin; hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype. ( CSP )] (UMLS (NCI) C0020217) =Neoplastic Process ;
=female reproductive system cancer;
Trophoblastic Neoplasm;
Pregnancy Disorder;
=Chorioadenoma;
|
- 2. (1)-4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-phenylene Dipivalate Hydrochloride
- [An ester with sympathomimetic activities. Dipivefrin hydrochloride is a prodrug of epinephrine that, due to its greater lipophilicity, allows for better penetration into the anterior chamber. Once inside the eye, dipivefrin hydrochloride is converted by hydrolysis to epinephrine. Epinephrine enhances the outflow of aqueous humor and decreases the production of aqueous humor by vasoconstriction. This leads to a reduction in intraocular pressure. ( NCI )] (UMLS (NCI) C0700488) =Organic Chemical; Pharmacologic Substance =DIPIVEFRIN;
=DIPIVEFRIN HYDROCHLORIDE 0.1 %;
| - 52. Hydeltra
- (UMLS (NCI) C0702183) =Steroid; Pharmacologic Substance
|
- 3. (1-Hydroxyethylidene)bisphosphonic Acid
- [As a member of the family of drugs known as bisphosphonates, etidronate differs from endogenous pyrophosphate in its resistance to enzymatic hydrolysis. This agent adsorbs to hydroxyapatite cells and reduces the number of osteoclasts, thereby inhibiting abnormal bone resorption. Etidronate may also directly stimulate bone formation by osteoblasts. (NCI) ( NCI )] (UMLS (NCI) C0015121) =Organophosphorus Compound; Pharmacologic Substance ;
=biphosphonate;
=EHDP;
Risedronic Acid;
| - 53. Hydra
- [A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals. ( MSH )] (UMLS (CSP) C0020222) =Invertebrate ;
|
- 4. 1(3-hydroxy-2-phosphonomethoxypropyl) Cytosine
- [1(3-hydroxy-2-phosphonomethoxypropyl) cytosine; potent selective inhibitor of human cytomegalovirus replication; used in CMV retinitis therapy. ( CSP )] (UMLS (NCI) C0286079) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=[AM800] ANTIVIRALS;
4-Amino-2(1H)-pyrimidinone;
Organophosphorus Compounds;
cytosine analog =CIDOFOVIR 75 MG/ML | - 54. hydralazine/IFN-A
- (UMLS (NCI) C0338171) =Therapeutic or Preventive Procedure
|
- 5. 1,1-Hydrazodibenzene
- [A colorless, crystalline compound that emits toxic fumes of nitrogen oxides when heated to decomposition. Hydrazobenzene has been used primarily in the dye manufacturing industry as the precursor of the dye intermediate benzidine and is also used as an intermediate in the manufacture of pharmaceuticals. Exposure to this substance irritates the skin, nose, throat and lungs and can eventually lead to liver, kidney and brain damage. Hydrazobenzene is reasonably anticipated to be a human carcinogen based on evidence of carcinogenicity in experimental animals. (NCI05) ( NCI )] (UMLS (NCI) C0063069) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 55. hydration
- [Combining with water. ( NCI )] (UMLS (NCI) C1321013) =Finding
|
- 6. 1-(4'-Hydroxy-3'-coumarinyl)-1-phenyl-3-butanone
- [synthetic coumarin anticoagulant. ( CSP )] (UMLS (NCI) C0043031) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance =4-Hydroxycoumarins;
[BL100] ANTICOAGULANTS;
2H-1-Benzopyran-2-one;
=Prothromadin;
| - 56. hydrazine
- [colorless, gaseous diamine, H2N-NH2, or its substitution derivatives. ( CSP )] (UMLS (CSP) C0020233) =Organic Chemical ;
=azo compound;
Organic Chemical =1(2H)-Phthalazinone Hydrazone;
INH;
methylhydrazine;
PHENELZINE;
phenylhydrazine;
Benzethyzin;
(-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic Acid;
INH;
PHENELZINE;
|
- 7. 13-Hydroxydaunomycin
- [An anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Duborimycin exhibits cytotoxic activity through topoisomerase-mediated interaction with DNA, thereby inhibiting DNA replication and repair and RNA and protein synthesis. (NCI04) ( NCI )] (UMLS (NCI) C0057159) =Organic Chemical; Pharmacologic Substance ;
| - 57. Hydrazine Sulfate
- [A substance that has been studied as a treatment for cancer and as a treatment for cachexia (body wasting) associated with advanced cancer. ( NCI )] (UMLS (NCI) C0063067) =Inorganic Chemical
|
- 8. 14-Hydroxydaunorubicin Hydrochloride
- [The hydrochloride salt of doxorubicin, an anthracycline antibiotic with antineoplastic activity. Doxorubicin, isolated from Streptomyces peucetius var. caesius, is the hydroxylated congener of daunorubicin. Doxorubicin intercalates between base pairs in the DNA helix, thereby preventing DNA replication and ultimately inhibiting protein synthesis. Additionally, doxorubicin inhibits topoisomerase II which results in an increased and stabilized cleavable enzyme-DNA linked complex during DNA replication and subsequently prevents the ligation of the nucleotide strand after double-strand breakage. Doxorubicin also forms oxygen free radicals resulting in cytotoxicity secondary to lipid peroxidation of cell membrane lipids; the formation of oxygen free radicals also contributes to the toxicity of the anthracycline antibiotics, namely the cardiac and cutaneous vascular effects. ( NCI )] (UMLS (NCI) C0546861) =Organic Chemical; Pharmacologic Substance =(8S-cis)-10-[(3-Amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroacetyl)-1-methoxy-5,12-naphthacenedione;
=DOXORUBICIN HYDROCHLORIDE 10 MG;
DOXORUBICIN HYDROCHLORIDE 100 MG;
DOXORUBICIN HYDROCHLORIDE 150 MG;
DOXORUBICIN HYDROCHLORIDE 2 MG/ML;
DOXORUBICIN HYDROCHLORIDE 200 MG;
DOXORUBICIN HYDROCHLORIDE 50 MG;
DOXORUBICIN HYDROCHLORIDE 20 MG;
DOXORUBICIN HYDROCHLORIDE 5 MG/ML | - 58. hydrazone
- [compound formed from an aldehyde or ketone by the action of phenylhydrazine. ( CSP )] (UMLS (CSP) C0020235) =Organic Chemical ;
=azo compound;
=1,1'-[(methylethanediylidene)dinitrilo)diguanidine;
thiosemicarbazone |
- 9. 17 hydroxycorticosteroid
- [A group of hydroxycorticosteroids bearing a hydroxy group at the 17-position. Urinary excretion of these compounds is used as an index of adrenal function. They are used systemically in the free alcohol form, but with esterification of the hydroxy groups, topical effectiveness is increased. ( MSH )] (UMLS (CSP) C0000163) =Steroid; Hormone ;
| - 59. Hydrea
- (UMLS (NCI) C0591617) =Organic Chemical; Pharmacologic Substance ;
|
- 10. 17-Hydroxy-7alpha-mercapto-3-oxo-17alpha-pregn-4-ene-21-carboxylic Acid, gamma Lactone, Acetate
- [potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules; used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis; its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. ( CSP )] (UMLS (NCI) C0037982) =Steroid; Pharmacologic Substance =aldosterone inhibitor;
LACTONE;
C21 steroid;
Pregnenes;
[CV704] POTASSIUM-SPARING/COMBINATIONS DIURETICS;
=SPIRONOLACTONE POWDER (GM);
SPIRONOLACTONE 100 MG;
SPIRONOLACTONE 25 MG;
SPIRONOLACTONE 50 MG;
| - 60. hydrocarbon
- [organic compound that contains carbon and hydrogen only. ( CSP )] (UMLS (CSP) C0020242) =Organic Chemical ;
=Organic Chemical;
=alkane;
alkene;
alkyne;
lipid;
Hydrocarbons, Acyclic;
Hydrocarbons, Cyclic;
Halogenated Hydrocarbon;
Paraffin;
petrolatum;
terpene |
- 11. 2 hydroxyacid oxidase
- [ ] (UMLS (CSP) C0597779) =Amino Acid, Peptide, or Protein; Enzyme
| - 61. hydrocarbon oxidoreductase
- [ ] (UMLS (CSP) C0596733) =Amino Acid, Peptide, or Protein; Enzyme =dehydrogenase;
=fumarate hydrogenase;
3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 2;
acyl coA dehydrogenase;
|
- 12. 2-Hydroxy-1,2,3-propanetricarboxylic Acid
- [A tricarboxylic acid found in citrus fruits. Citric acid is used as an excipient in pharmaceutical preparations due to its antioxidant properties. It maintains stability of active ingredients and is used as a preservative. It is also used as an acidulant to control pH and acts as an anticoagulant by chelating calcium in blood. ( NCI )] (UMLS (NCI) C0055819) =Organic Chemical; Pharmacologic Substance; Biologically Active Substance =[TN410] CITRATES;
2-Hydroxy-1,2,3-propanetricarboxylic Acid;
[PH000] PHARMACEUTICAL AIDS / REAGENTS;
=Citrate of Magnesia;
CITRATE;
CITRIC ACID More… | - 62. HYDROCELE CANAL NUCK-FEM
- [ ] (UMLS (ICD9CM) C0156420) =Anatomical Abnormality
|
- 13. 2-Hydroxy-1,2,3-propanetricarboxylic Acid, Calcium Salt (2:3)
- [The citrate salt of calcium. An element necessary for normal nerve, muscle, and cardiac function, calcium as the citrate salt helps to maintain calcium balance and prevent bone loss when taken orally. This agent may also be chemopreventive for colon and other cancers. (NCI04) ( NCI )] (UMLS (NCI) C0108101) =Organic Chemical; Pharmacologic Substance; Biologically Active Substance =[TN402] CALCIUM;
[TN410] CITRATES;
CITRATE;
TO BE DELETED INGREDIENT PREPARATIONS =CALCIUM (AS CITRATE) 200 MG;
CALCIUM (AS CITRATE) 500 MG;
LONALAC POWDER,ORAL;
CALCIUM CITRATE 1040 MG;
CALCIUM CITRATE 315 MG;
CALCIUM CITRATE 950 MG;
| - 63. HYDROCELE NEC
- [ ] (UMLS (ICD9CM) C0029837) =Disease or Syndrome; Anatomical Abnormality
|
- 14. 2-Hydroxy-1,2,3-propanetricarboxylic Acid, Potassium Salt
- [The potassium salt form of citrate with alkalinizing property. Following absorption, potassium citrate causes increased plasma bicarbonate concentration, thereby raising blood and urinary pH. A simultaneous decrease in calcium ion activity occurs as a result of increasing calcium complex formation with dissociated anions. Levels of urinary citrate are increased due to modification of the renal handling of citrate. By promoting excretion of free bicarbonate ion and by increasing urinary pH in addition to an increased ionization of uric acid to more soluble urate ions, this agent exerts the alkalizing and anti-urolithic effect. ( More…
| - 64. HYDROCEPH FETUS-ANTEPART
- [ ] (UMLS (ICD9CM) C0156991) =Disease or Syndrome ;
|
- 15. 2-Hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)propanamide
- (UMLS (NCI) C0122812) =Organic Chemical; Pharmacologic Substance
| - 65. HYDROCEPH FETUS-DELIVER
- [ ] (UMLS (ICD9CM) C0156990) =Disease or Syndrome ;
|
- 16. 2-Hydroxy-4-methoxybenzophenone
- [A benzophenone derivative used as a sunscreen agent. Oxybenzone absorbs UVB and UVA II rays, resulting in a photochemical excitation and absorption of energy. Upon return to ground state, the absorbed energy results in emission of longer wavelength radiation and decreased skin penetration of radiation which reduces the risk of DNA damage. ( NCI )] (UMLS (NCI) C0069803) =Organic Chemical; Pharmacologic Substance ;
=Benzophenones;
[DE300] SUN PROTECTANTS/SCREENS, TOPICAL =LANOLIN/MINERAL OIL/OXYBENZONE OIL,TOP;
OCTYL METHOXYCINNAMATE/OCTYL SALICYLATE/OXYBENZONE SPF-15 LOTION;
OXYBENZONE/PABA (PRE-SUN 46) LOTION;
OXYBENZONE/PADIMATE O LOTION;
OXYBENZONE/PETROLATUM OINT,TOP;
SUNSCREEN-15 PABA-FREE COMBINATION GEL;
SUNSCREEN-30 PABA-FREE COMBINATION LOTION;
OXYBENZONE 6 %;
OXYBENZONE 2 %;
OXYBENZONE 2.3 %;
OXYBENZONE 5 %;
OXYBENZONE 3 %;
ALPHA KERI BATH OIL;
BATH OIL;
AMINOBENZOIC ACID/BENZOPHENONE LOTION (ML);
THERI BATH OIL;
NUTRADERM BATH OIL | - 66. HYDROCEPHAL FETUS-UNSPEC
- [ ] (UMLS (ICD9CM) C0156989) =Disease or Syndrome ;
|
- 17. 2-Hydroxy-5-[[4-[(2-pyridinylamino)sulfonyl]phenyl]azo]benzoic Acid
- [A synthetic salicylic acid derivative with affinity for connective tissues containing elastin and formulated as a prodrug, antiinflammatory Sulfasalazine acts locally in the intestine through its active metabolites, sulfamide 5-aminosalicylic acid and salicylic acid, by a mechanism that is not clear. It appears inhibit cyclooxygenase and prostaglandin production and is used in the management of inflammatory bowel diseases. (NCI04) ( NCI )] (UMLS (NCI) C0036078) =Organic Chemical; Pharmacologic Substance =sulfonamide;
[GA900] GASTRIC MEDICATIONS, OTHER =SULFASALAZINE 500 MG;
SULFASALAZINE 250 MG/5ML;
| - 67. Hydrocephalic fetus causing disproportion
- [ ] (UMLS (ICD9CM) C0156988) =Finding ;
|
- 18. 2-Hydroxyamino-2-ethanal
- [A urea analogue with bacterial urease inhibiting activity. Acetohydroxamic acid is used as adjunctive therapy in the treatment of urinary tract infections caused by urease-producing bacteria. In addition, this drug is used in the prophylaxis and treatment of struvite renal calculi, whose formation is favored by urease-producing bacteria, by dissolving renal stones as well as preventing the formation of new crystals. (NCI05) ( NCI )] (UMLS (NCI) C0050451) =Organic Chemical; Pharmacologic Substance =Hydroxamic Acids;
Unclassified Ingredient Preparations =ACETOHYDROXAMIC ACID 250 MG;
| - 68. hydrocephalus
- [excessive accumulation of cerebrospinal fluid within the cranium which may be a congenital or acquired disorder; hydrocephalus ex-vacuo refers to ventricular dilation that occurs as a result of brain substance loss from cerebral infarction and other conditions. ( CSP )] (UMLS (NCI) C0020255) =Disease or Syndrome =Infant, Newborn, Diseases;
Intracranial Hypertension;
CEREB DEGENERATION NOS;
congenital brain disorder =Dandy-Walker Syndrome;
Hydrocephalus, Normal Pressure;
|
- 19. 2-Hydroxybenzoic Acid
- [A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics. (From Dorland's, 28th ed) ( MSH )] (UMLS (NCI) C0036079) =Organic Chemical; Pharmacologic Substance =2-Hydroxybenzoic Acid;
Salicylic Acids;
[DE752] ANTIACNE AGENTS, TOPICAL;
[DE500] KERATOLYTICS/CAUSTICS, TOPICAL =Salicylates;
PYRITHIONE ZINC 1% SHAMPOO;
BI SUBSALICYLATE 260MG/MG AL SILICATE/SAL AC/NA SALICYLATE/30ML;
BI SUBSALICYLATE 459MG/MG AL SILICATE/SAL AC/NA SALICYLATE/30ML;
COAL TAR 5%/LASSAR PASTE,TOP;
Coal Tar / Salicylic Acid Topical Cream;
DRYTEX LOTION;
EUCALYPTUS OIL/ME SALICYLATE/PEPPERMINT OIL/SALICYLIC AC LIQ,TOP;
GORDOMATIC PWDR,TOP;
SALICYLIC ACID GEL,TOP;
SALICYLIC ACID POWDER (GM);
NAIL FUNGAL SOLN,TOP;
COAL TAR/SALICYLIC ACID LOTION;
CARMEX OINT,TOP;
SALICYLIC ACID 0.1 %;
SALICYLIC ACID 4 GM;
SALICYLIC ACID 13.57 %;
SALICYLIC ACID 40 %;
SALICYLIC ACID 0.5 %;
SALICYLIC ACID 1 %;
SALICYLIC ACID 5 %;
SALICYLIC ACID 2.5 %;
SALICYLIC ACID 12.2 %;
SALICYLIC ACID 2.35 %;
SALICYLIC ACID 26 %;
SALICYLIC ACID 6 %;
SALICYLIC ACID 50 %;
SALICYLIC ACID 12 %;
SALICYLIC ACID 1.8 %;
SALICYLIC ACID 4 %;
SALICYLIC ACID 10 %;
SALICYLIC ACID 16.7 %;
SALICYLIC ACID 30 %;
SALICYLIC ACID 2.25 %;
SALICYLIC ACID 24 %;
SALICYLIC ACID 14.2 %;
SALICYLIC ACID 1.5 %;
SALICYLIC ACID 2 %;
SALICYLIC ACID 3 %;
SALICYLIC ACID 17 %;
SALICYLIC ACID 25 %;
SALICYLIC ACID 60 %;
2-Hydroxybenzoic Acid | - 69. HYDROCODONE
- [A semisynthetic hydrogenated codeine derivative and opioid agonist with analgesic and antitussive effects. Hydrocodone primarily binds to and activates the mu-opioid receptor in the central nervous system (CNS). This leads to analgesia, euphoria, respiratory depression, miosis, decreased gastrointestinal motility, cough suppression and physical dependence. Hydrocodone is converted to hydromorphone by the cytochrome P450 enzyme CYP2D6. ( NCI )] (UMLS (NCI) C0020264) =Organic Chemical; Pharmacologic Substance ;
=[CN101] OPIOID ANALGESICS;
codeine;
[RE301] OPIOID-CONTAINING ANTITUSSIVES/EXPECTORANTS;
=HYDROCODONE BITARTRATE;
HYDROCODONE POLISTIREX;
HYDROCODONE RESIN COMPLEX;
HYDROCODONE BITARTRATE;
HYDROCODONE POLISTIREX;
HYDROCODONE RESIN COMPLEX;
Hydrocodone 1 MG/ML;
HYDROCODONE 10 MG;
HYDROCODONE 7.5 MG;
HYDROCODONE 5 MG;
|
- 20. 2-Hydroxypropanoic Acid Sodium Salt
- [A sodium salt of racemic or inactive lactic acid with alkalinizing and electrolyte replenishing property. Upon metabolism, sodium lactate is converted to bicarbonate, thereby increasing plasma bicarbonate, which facilitates removal of hydrogen ion and lactate from blood stream and leads to raised blood pH. ( NCI )] (UMLS (NCI) C0142874) =Organic Chemical; Pharmacologic Substance ;
=lactate;
[TN102] IV SOLUTIONS WITH ELECTROLYTES;
[TN499] ELECTROLYTES/MINERALS, OTHER;
=MASSENGILL DISPOSABLE DOUCHE;
Carboxymethylcellulose 5 MG/ML Ophthalmic Solution;
MASSENGILL DISPOSABLE DOUCHE BELLE-MAI,VAG;
SODIUM LACTATE 5 MEQ/ML;
MASSENGILL DOUCHE,VAG;
Sodium Lactate 3.1 MG/ML;
Sodium Lactate 2.6 MG/ML;
Sodium Lactate 2.2 MG/ML;
SODIUM LACTATE 0.062 GM/100ML;
SODIUM LACTATE 0.392 GM/100ML;
SODIUM LACTATE 138 MG/100ML;
SODIUM LACTATE 155 MG/100ML;
SODIUM LACTATE 224 MG/100ML;
SODIUM LACTATE 246 MG/100ML;
SODIUM LACTATE 25 ML;
SODIUM LACTATE 280 MG/100ML;
SODIUM LACTATE 390 MG/100ML;
SODIUM LACTATE 392 MG/100ML;
SODIUM LACTATE 448 MG/100ML;
SODIUM LACTATE 50 ML;
SODIUM LACTATE 500 MG/100ML;
SODIUM LACTATE 62 MG/100ML;
SODIUM LACTATE 670 MG/100ML;
SODIUM LACTATE 672 MG/100ML;
SODIUM LACTATE 672.4 MG/100ML;
SODIUM LACTATE 89.6 MG/100ML;
SODIUM LACTATE 0.056 %;
SODIUM LACTATE 5 %;
SODIUM LACTATE 1;
PODOFILOX 0.5 %WW TOPICAL SOLUTION;
| - 70. Hydrocodone/Acetaminophen
- [A combination preparation of the analgesic acetaminophen and the semisynthetic opioid agonist hydrocodone with analgesic and antitussive activities. Acetaminophen exerts its analgesic activity by inhibiting prostaglandin synthesis while hydrocodone exerts its analgesic activity by binding to the mu-receptors in the central nervous system (CNS), thereby mimicking the effects of endogenous opioids. ( NCI )] (UMLS (NCI) C0717367) =Organic Chemical; Pharmacologic Substance ;
|
- 21. 3-(3-Hydroxyanthraniloyl)alanine
- (UMLS (NCI) C0047472) =Organic Chemical; Pharmacologic Substance ;
| - 71. HYDROCORTAMATE
- (UMLS (NCI) C0544368) =Steroid; Pharmacologic Substance; Hormone
|
- 22. 3-(4-Hydroxyphenyl)-2H-1-benzopyran-7-ol
- [A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called signal transduction inhibitors. ( NCI )] (UMLS (NCI) C1134444) NV-06;
Phenoxodiol;
=Organic Chemical; Pharmacologic Substance | - 72. HYDROCORTAMATE HYDROCHLORIDE
- (UMLS (NCI) C1445700) =Steroid; Pharmacologic Substance; Hormone
|
- 23. 3-(Hydroxynitrosoamino)-L-alanine
- [An amino acid analog derived from Streptomyces alanosinicus, a purine antagonist, and an adenylosuccinate synthase inhibitor with antineoplastic properties. L-alanosine deprives MTAP-deficient (salvage pathway) tumor cells of de novo synthesized adenosine and is probably responsible for diminished DNA synthesis. The clinical use of L-alanosine may be narrow due to its toxicity profile. (NCI04) ( NCI )] (UMLS (NCI) C0051066) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
| - 73. HYDROCORTISONE ACETATE
- [The synthetic acetate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties. Hydrocortisone acetate initially binds to the cytoplasmic glucocorticoid receptor; then the receptor-ligand complex is translocated to the nucleus where it initiates the transcription of genes encoding for anti-inflammatory mediators, such as cytokines and lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes. ( NCI )] (UMLS (NCI) C0063077) =Steroid; Pharmacologic Substance ;
=(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione;
[OR900] DENTAL AND ORAL AGENTS, TOPICAL OTHER;
[OP300] ANTI-INFLAMMATORIES, TOPICAL OPHTHALMIC;
=HYDROCORTISONE ACETATE 0.5 %;
HYDROCORTISONE ACETATE 1 %WV;
HYDROCORTISONE ACETATE 10 MG;
HYDROCORTISONE ACETATE 10 MG/GM;
HYDROCORTISONE ACETATE 25 GM;
HYDROCORTISONE ACETATE 5 MG;
HYDROCORTISONE ACETATE 50 MG/ML;
HYDROCORTISONE ACETATE 25 MG;
HYDROCORTISONE ACETATE 10 %;
HYDROCORTISONE ACETATE 30 MG;
HYDROCORTISONE ACETATE 25 MG/ML;
HYDROCORTISONE ACETATE 15 MG;
HYDROCORTISONE ACETATE 2.5 %;
HYDROCORTISONE ACETATE 1 %;
|
- 24. 3-Hydroxy-2-phenyl-4H-1-benzopyran-4-one
- (UMLS (NCI) C0284815) =Organic Chemical; Pharmacologic Substance
| - 74. Hydrocortisone Cypionate
- (UMLS (NCI) C0612688) =Steroid; Pharmacologic Substance ;
=(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione;
=HYDROCORTISONE CYPIONATE 10 MG/5ML |
- 25. 3-hydroxy-3-methylglutaryl-Coenzyme A Reductase
- [Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. In liver enzymes of this class are involved in cholesterol biosynthesis. ( MSH )] (UMLS (NCI) C0063164) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 75. Hydrocortisone Sodium Phosphate
- (UMLS (NCI) C0770559) HYDROCORTISONE SODIUM PHOSPHATE PREPARATION;
=Steroid; Pharmacologic Substance ;
=(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione;
=HYDROCORTISONE SODIUM PHOSPHATE 50 MG/ML;
|
- 26. 3-Hydroxy-5-methoxy-6-methyl-2-pentyl-4H-pyran-4-one
- (UMLS (NCI) C0647702) =Organic Chemical; Pharmacologic Substance
| - 76. Hydrocortisone Used as a Placebo
- [Hydrocortisone used as a placebo in comparative studies. ( NCI )] (UMLS (NCI) C0281715) =Therapeutic or Preventive Procedure
|
- 27. 3-Hydroxy-alpha-methyl-L-tyrosine
- [A phenylalanine derivative and an aromatic amino acid decarboxylase inhibitor with antihypertensive activity. Methyldopa is a prodrug and is metabolized in the central nervous system. The antihypertensive action of methyldopa seems to be attributable to its conversion into alpha-methylnorepinephrine, which is a potent alpha-2 adrenergic agonist that binds to and stimulates potent central inhibitory alpha-2 adrenergic receptors. This results in a decrease in sympathetic outflow and decreased blood pressure. ( NCI )] (UMLS (NCI) C0025741) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Neuroreactive Substance or Biogenic Amine =dihydroxyphenylalanine;
[CV490] ANTIHYPERTENSIVES, OTHER =(-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic Acid;
METHYLDOPATE;
METHYLDOPA 250 MG;
METHYLDOPA 125 MG;
METHYLDOPA 500 MG | - 77. Hydrocortisone/Ketoconazole
- (UMLS (NCI) C0935705) =Therapeutic or Preventive Procedure
|
- 28. 3-Hydroxyestra-1,3,5(10),7-tetraen-17-one
- [A naturally occurring steroid with estrogenic activity obtained from the urine of pregnant mares. ( NCI )] (UMLS (NCI) C0014654) =Steroid; Pharmacologic Substance; Hormone
| - 78. Hydrodiuril
- (UMLS (NCI) C0700698) =Organic Chemical; Pharmacologic Substance ;
|
- 29. 3-hydroxymethyl-5-aziridinyl-1-methyl-2-(1H-indole-4,7-dione) prop-beta-en-alpha-ol
- [A bioreductive indoloquinone prodrug with potential antineoplastic and radiosensitizing activities. Apaziquone, an analogue of mitomycin C, becomes activated after being reduced by various reductases depending on tissue types. The activated metabolite and the reactive free radicals generated during reduction process cause DNA damages, thereby leading to induction of apoptosis. Furthermore, this agent displays cancer selectivity against both the hypoxic solid tumors, which exhibits higher expression of cytochrome P450 reductase, and also against the well-oxygenated malignant cells that overexpress the bioreductive enzyme NQO1 (NAD(P)H: quinone oxidoreductase). ( NCI )] (UMLS (NCI) C0095568) =Organic Chemical; Pharmacologic Substance ;
| - 79. hydrofluoric acid
- [Hydrofluoric acid. A solution of hydrogen fluoride in water. It is a colorless fuming liquid which can cause painful burns. ( MSH )] (UMLS (CSP) C0020274) =Hazardous or Poisonous Substance; Inorganic Chemical ;
=Acids, Noncarboxylic;
Fluorine Compounds;
Inactive Ingredient Preparations;
=[TN407] FLUORIDE;
HYDROFLUORIC ACID 42.6 MG;
HYDROFLUORIC ACID 7.1 MG;
HYDROFLUORIC ACID 729 MG;
HYDROFLUORIC ACID 0.17 %;
HYDROFLUORIC ACID 0.2 %;
HYDROFLUORIC ACID 0.28 % |
- 30. 4 hydroxynonenal
- [ ] (UMLS (CSP) C0048297) =Organic Chemical; Pharmacologic Substance
| - 80. hydrogel lenticular implantation
- [ ] (UMLS (CSP) C0599292) =Therapeutic or Preventive Procedure
|
- 31. 4 hydroxyphenylpyruvate dioxygenase
- [An enzyme that catalyzes the conversion of 4-hydroxyphenylpyruvate plus oxygen to homogentisic acid and carbon dioxide. EC 1.13.11.27. ( MSH )] (UMLS (CSP) C0000507) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 81. hydrogen bond
- [strong intermolecular forces produced by the attraction of a hydrogen atom, already covalently bonded to one electronegative atom, to a second electronegative atom of the same molecule or an adjacent molecule; these bonds are found in compounds containing strong electronegative atoms such as fluorine, oxygen, or nitrogen. ( CSP )] (UMLS (CSP) C0020276) =Natural Phenomenon or Process =chemical bond;
|
- 32. 4-HYDROXY BUTYRIC ACID
- [A naturally occurring short-chain fatty acid, and immediate precursor of gamma amino butyric acid (GABA) with neuromodulatory and anesthetic properties. Gamma-Hydroxybutyric Acid (GHB) is found in all human tissues, with the highest concentration in the brain. This agent stimulates the GHB receptor, and to a lesser extent GABA-B receptors. Although, the precise function and metabolic pathways of GHB are not fully understood, this agent easily crosses the blood-brain barrier, and affects the activities and levels of dopamine, acetylcholine, dynorphin and serotonin. The primary effect of GHB is central nervous system depression, thereby, its main usage is to induce anesthesia. ( NCI )] (UMLS (NCI) C0673093) =Organic Chemical; Pharmacologic Substance; Biologically Active Substance
| - 82. hydrogen channel
- [molecule-sized pores in biomembranes that permit the passage of hydrogen ions, and the proteins that form such pores and control their permeability; especially, a passage in the inner mitochondrial membrane that facilitates the movement of protons out of the mitochondrial matrix during oxidative phosphorylation. ( CSP )] (UMLS (CSP) C0596734) =Amino Acid, Peptide, or Protein; Biologically Active Substance =Ion Channel;
|
- 33. 4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
- [An oxicam derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Unlike traditional nonselective NSAIDs, meloxicam preferentially inhibits the activity of cyclo-oxygenase II (COX-II), resulting in a decreased conversion of arachidonic acid into prostaglandin precursors. The resulting decrease in prostaglandin synthesis is responsible for the therapeutic effects of meloxicam. ( NCI )] (UMLS (NCI) C0083381) =Organic Chemical; Pharmacologic Substance =thiazine;
thiazole;
[MS102] NONSALICYLATE NSAIS, ANTIRHEUMATIC;
=MELOXICAM 7.5 MG;
MELOXICAM 15 MG;
| - 83. hydrogen electrode
- [ ] (UMLS (CSP) C0598355) =Manufactured Object ;
|
- 34. 4-Hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboximide-1,1-dioxide
- [4-hydroxy-2-methyl-N-2-pyridyl-2H-1,2- benzothiazine-3-carboxamide- 1,1-dioxide; nonsteroidal antiinflammatory drug (NSAID) which functions by inhibiting prostaglandin synthesis; effective against colon cancer. ( CSP )] (UMLS (NCI) C0031990) =Organic Chemical; Pharmacologic Substance ;
=antiinflammatory agent;
[AN000] ANTINEOPLASTICS;
thiazine;
antiarthritic agent;
[MS102] NONSALICYLATE NSAIS, ANTIRHEUMATIC;
=PIROXICAM 10 MG;
PIROXICAM 20 MG;
| - 84. hydrogen fluoride
- [ ] (UMLS (CSP) C0520465) =Hazardous or Poisonous Substance; Inorganic Chemical ;
|
- 35. 4-hydroxy-3,7-dimethoxy-17-methylmorphin-7-en-6-one
- [An alkaloid isolated from the root of Sinomenium acutum with immunomodulatory and potential anti-angiogenic and activities. Although the mechanism of action remains to be fully elucidated, sinomenine appears to inhibit endothelial proliferation mediated through basic fibroblast growth factor (bFGF), which may contribute to its anti-angiogenic effect. In Chinese medicine, this agent has a long track-record in treating arthritis, which is accounted by its ability to inhibit proliferation of synovial fibroblasts and lymphocytes. In addition, sinomenine has been shown to suppress expressions of genes involved in inflammation and apoptosis, such as interleukin-6, a pleiotropic inflammatory cytokine and JAK3 (Janus kinase 3), Daxx (death-associated protein 6), plus HSP27 (heat shock 27kDa protein 1), respectively. ( NCI )] (UMLS (NCI) C0074568) =Organic Chemical; Pharmacologic Substance ;
| - 85. hydrogen peroxide generating oxidase
- [nonEC. ( CSP )] (UMLS (CSP) C0897757) oxygen generating oxidase;
oxygen producing enzyme;
respiratory burst oxidase;
superoxide forming enzyme =Amino Acid, Peptide, or Protein; Enzyme ;
=NAD(P)H oxidoreductase;
|
- 36. 4-Hydroxyacetanilide
- [analgesic antipyretic derivative of acetanilide; weak antiinflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage. ( CSP )] (UMLS (NCI) C0000970) =Organic Chemical; Pharmacologic Substance ;
| - 86. hydrogen sulfide
- [toxic gas, H2S. ( CSP )] (UMLS (CSP) C0020282) =Indicator, Reagent, or Diagnostic Aid; Hazardous or Poisonous Substance; Inorganic Chemical =Acids, Noncarboxylic;
Gas;
sulfide;
sulfur compound =sulfide |
- 37. 4-Hydroxyandrost-4-ene-3,17-dione
- [A synthetic steroidal substance with antineoplastic activity. Formestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. (NCI04) ( NCI )] (UMLS (NCI) C0048306) =Organic Chemical; Pharmacologic Substance
| - 87. hydrogen transport
- [movement of hydrogen ions (protons) across biological membranes; may be active, passive, or facilitated. ( CSP )] (UMLS (CSP) C0596735) =Cell Function ;
=biological transport;
|
- 38. 4-hydroxyanisole
- [A synthetic derivate of hydroquinone and depigmenting agent. Although the exact mechanism of the depigmenting effects of mequinol remains unclear, it may exert its effect by oxidation of tyrosinase to cytotoxic products in melanocytes. Mequinol may also act by competitively inhibiting the formation of melanin precursors. ( NCI )] (UMLS (NCI) C0048318) =Organic Chemical; Pharmacologic Substance
| - 88. hydrogenase
- [specific enzyme (EC 1.18.99.1) that catalyzes the conversion of H+ to hydrogen gas via oxidation of ferredoxin; do not use for general term to cover other hydrogenating enzymes. ( CSP )] (UMLS (CSP) C0020284) =Amino Acid, Peptide, or Protein; Enzyme ;
=miscellaneous oxidoreductase;
|
- 39. 4-Hydroxytamoxifen
- [A tamoxifen metabolite with both estrogenic and anti-estrogenic effects. 4-hydroxytamoxifen has a higher affinity for the estrogen receptor than tamoxifen, and functions as an antagonist in breast cancer cells. (NCI04) ( NCI )] (UMLS (NCI) C0048403) =Organic Chemical; Pharmacologic Substance
| - 89. hydrogenation
- [Addition of hydrogen to a compound, especially to an unsaturated fat or fatty acid. (From Stedman, 26th ed) ( MSH )] (UMLS (CSP) C0020286) =Natural Phenomenon or Process
|
- 40. 4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,2-benzenediol Hydrochloride
- [The hydrochloride salt form of isoproterenol, a synthetic catechol compound and potent beta adrenergic agonist with peripheral vasodilator, bronchodilator, and cardiac stimulating properties. Isoproterenol exerts its effect on the beta1-receptors in the myocardium, thereby increasing heart rate and cardiac output. In addition, isoproterenol acts on beta2-receptors in bronchiolar and vascular smooth muscle, thereby causing smooth muscle relaxation. ( NCI )] (UMLS (NCI) C0282210) =Organic Chemical; Pharmacologic Substance =isoprenaline;
=ISOPROTERENOL HYDROCHLORIDE 0.2 MG/ML;
| - 90. hydrolase
- [Enzymes (EC class 3) cleaving substrates with addition of H2O at the point of cleavage; e.g., esterases, phosphatases, nucleases, peptidases. SYN hydrolyzing enzymes. ( NCI )] (UMLS (CSP) C0020289) =Amino Acid, Peptide, or Protein; Enzyme ;
=enzyme;
Enzymatic Agents =Ester Hydrolase;
glycosidase;
Enzymes, Proteolytic;
acid anhydride hydrolase;
carbon carbon hydrolase;
carbon nitrogen hydrolase;
ether hydrolase;
hepatic lipase;
amidinohydrolase;
aminohydrolase;
Ester Hydrolase;
glycosidase;
Pancreatin;
Enzymes, Proteolytic |
- 41. 4-[[Hydroxy(octadecyloxy)phosphinyl]oxy]-1,1-dimethylpiperidinium, Inner Salt
- [An anticancer drug that belongs to the family of drugs called alkyl phospholipids. ( NCI )] (UMLS (NCI) C0754570) Octadecyl-(N,N-dimethylpiperidino-4-yl)phosphate;
Octadecylphosphopiperidine;
PERIFOSINE;
=Organophosphorus Compound; Pharmacologic Substance | - 91. Hydrolase Family Gene
- (UMLS (NCI) C1334064) Hydrolase Gene =Gene or Genome ;
|
- 42. 5 hydroxytryptamine
- [biochemical messenger and regulator, synthesized from tryptophan; in humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. ( CSP )] (UMLS (CSP) C0036751) =Organic Chemical; Neuroreactive Substance or Biogenic Amine ;
=Neurotransmitter;
tryptamine | - 92. hydrolysis
- [process of cleaving a chemical compound by the addition of a molecule of water. ( CSP )] (UMLS (NCI) C0020291) =Natural Phenomenon or Process =solvolysis;
|
- 43. 5,5'-[(2-Hydroxy-1,3-propanediyl)bis(oxy)]bis[4-oxo-4H-1-benzopyran-2-carboxylic Acid], Disodium Salt
- [The sodium salt form of cromolyn, a mast cell stabilizer with anti-inflammatory activity. Cromolyn sodium probably interferes with the antigen-stimulated calcium transport across the mast cell membrane, thereby inhibiting mast cell release of histamine, leukotrienes, and other substances that cause hypersensitivity reactions. Cromolyn sodium also inhibits eosinophil chemotaxis. ( NCI )] (UMLS (NCI) C0012694) =Organic Chemical; Pharmacologic Substance ;
=Chromones;
cromoglycic acid =CROMOLYN SODIUM 800 MCG/ACTUAT;
CROMOLYN SODIUM 100 MG;
CROMOLYN SODIUM 4 %;
CROMOLYN SODIUM 100 MG/5ML;
CROMOLYN SODIUM 10 MG/ML;
| - 93. HYDROMYELIA
- (UMLS (ICD9CM) C0152444) =Congenital Abnormality
|
- 44. 5-Hydroxy-6-methyl-3,4-pyridinedimethanol Hydrochloride
- [The hydrochloride salt form of pyridoxine, a water-soluble vitamin B. Pyridoxine hydrochloride is converted into the active form, pyridoxal 5'-phosphate (PLP), an essential cofactor in many enzymatic activities including synthesis of amino acids, neurotransmitters, and sphingolipids. This vitamin is essential to red blood cell, nervous system, and immune systems functions and helps maintain normal blood glucose levels. ( NCI )] (UMLS (NCI) C0700496) =Organic Chemical; Pharmacologic Substance; Vitamin =[VT104] PYRIDOXINE;
=PYRIDOXINE HCL 0.3 MG;
MERITENE POWDER (CHOCOLATE);
MERITENE POWDER (MILK CHOCOLATE);
MERITENE POWDER More… | - 94. hydronaphthalene
- [ ] (UMLS (CSP) C0596736) =Organic Chemical ;
|
- 45. 5-Hydroxytryptamine (Serotonin) Receptor 2A Gene
- [This gene plays a role in G protein-coupled receptor signal transduction and sterol metabolism. ( NCI )] (UMLS (NCI) C1415809) HTR2A;
HTR2A Gene =Gene or Genome | - 95. hydronaphthylamine
- [ ] (UMLS (CSP) C0598920) =Organic Chemical ;
|
- 46. 5-Hydroxytryptamine (Serotonin) Receptor 3A Gene
- [This gene plays a role in neurotransmitter modulation and in chaperone activity. ( NCI )] (UMLS (NCI) C1333933) HTR3A;
HTR3A Gene =Gene or Genome ;
| - 96. hydronephrosis
- [distention of the pelvis and calices of the kidney with urine, as a result of obstruction of the ureter, with accompanying atrophy of the parenchyma of the organ. ( CSP )] (UMLS (NCI) C0020295) =Disease or Syndrome =Kidney Disease;
|
- 47. 6-Hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone Hydrochloride
- [The hydrochloride salt form of raloxifene, a selective benzothiophene estrogen receptor modulator (SERM) with lipid lowering effects and activity against osteoporosis. Raloxifene hydrochloride specifically binds to estrogen receptors in responsive tissue, including liver, bone, breast, and endometrium. The resulting ligand-receptor complex is translocated to the nucleus where, depending on the tissue type, it promotes or suppresses the transcription of estrogen-regulated genes, thereby exerting its agonistic or antagonistic effects. This agent functions as an estrogen agonist in lipid metabolism, thereby decreasing total and LDL cholesterol levels. In tissue like bone, it decreases bone resorption and bone turnover and increases bone mineral density. Raloxifene hydrochloride acts as an estrogen antagonist in uterine and breast tissue. This agent also exerts an anti-proliferative effect on estrogen-sensitive breast cancer. ( NCI )] (UMLS (NCI) C0618111) =Organic Chemical; Pharmacologic Substance ;
=[6-Hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone;
=RALOXIFENE HYDROCHLORIDE 60 MG | - 97. hydropathy
- [tendency of a chemical compound or molecular domain to be included (hydrophilicity) or excluded (hydrophobicity) from aqueous solvents; important in protein folding, structure, and binding and biological membrane structure; do not use for hydrotherapy. ( CSP )] (UMLS (CSP) C0596737) =Quantitative Concept ;
=Chemical Properties;
|
- 48. Hidrocele
- [Accumulation of serous fluid between the layers of membrane (tunica vaginalis) covering the TESTIS in the SCROTUM.(MSH)] (UMLS (ICPC) C1720771) (Hydrocele; (194); Hydrocele; Hydrokele; HYDROCELE; Hydrocele; Hydrozele; hidrotzela; hydrokele; Idrocele; HYDROCELE TESTIS; Hidrocelo; Hidrocele; HYDROCELE/VATTENBRACK) Hidrocelo; hidrotzela; Hydrocele; HYDROCELE NOS; HYDROCELE TESTIS; Hydrocele, unspecified; HYDROCELE/VATTENBRACK; hydrokele; Hydrozele; Idrocele =Disease or Syndrome =DISEASES OF MALE GENITAL ORGANS; Diagnosis/Diseases Component; Body System, Reproductive, Male;
| - 98. hydropericardium
- [ ] (UMLS (CSP) C0349077) =Pathologic Function
|
- 49. Hydaburg Cooperative Association
- (UMLS (HL7) C1550874) =Population Group =NativeEntityAlaska;
| - 99. Hydrophilic
- [The inherent characteristic of a molecule or substance to be soluble in water. ( NCI )] (UMLS (NCI) C0475370) =Quantitative Concept
|
- 50. hydantoin
- [group of anticonvulsants containing an allantoin heterocyclic base. ( CSP )] (UMLS (CSP) C0020209) =Organic Chemical; Pharmacologic Substance =imidazole;
imidazoledione =dantrolene;
5,5-Diphenyl-2,4-imidazolidinedione;
allantoin;
dantrolene;
3-ethyl-5-phenyl-2,4-imidazolidinedione;
MEPHENYTOIN;
5,5-Diphenyl-2,4-imidazolidinedione;
1,3-dimethylol-5,5-dimethylhydantoin | - 100. hydrophobia
- [acute infectious disease of the central nervous system affecting almost all mammals, including humans; it is caused by a rhabdovirus and usually spread by contamination with virus-laden saliva of bites inflicted by rabid animals; important animal vectors include the dog, cat, vampire bat, mongoose, skunk, wolf, raccoon, and fox. ( CSP )] (UMLS (CSP) C0034494) =Disease or Syndrome =Infection, Viral;
Rhabdoviridae Infections;
nervous system infection;
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