[A semisynthetic hydrogenated codeine derivative and opioid agonist with analgesic and antitussive effects. Hydrocodone primarily binds to and activates the mu-opioid receptor in the central nervous system (CNS). This leads to analgesia, euphoria, respiratory depression, miosis, decreased gastrointestinal motility, cough suppression and physical dependence. Hydrocodone is converted to hydromorphone by the cytochrome P450 enzyme CYP2D6. ( NCI )]
UMLS (NCI) C0020264 - Organic Chemical
- Pharmacologic Substance
Relation/PAR: [CN101] OPIOID ANALGESICS
codeine
[RE301] OPIOID-CONTAINING ANTITUSSIVES/EXPECTORANTS
Relation/CHD: HYDROCODONE BITARTRATE
HYDROCODONE POLISTIREX
HYDROCODONE RESIN COMPLEX
HYDROCODONE BITARTRATE
HYDROCODONE POLISTIREX
HYDROCODONE RESIN COMPLEX
Hydrocodone 1 MG/ML
HYDROCODONE 10 MG
HYDROCODONE 7.5 MG
HYDROCODONE 5 MG