[This protein is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. (LocusLink) ( NCI )]
UMLS (NCI) C0255034 - Amino Acid, Peptide, or Protein
- Biologically Active Substance
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