[A phenylalkylamine sympathomimetic amine with appetite depressant property. Phendimetrazine tartrate is a prodrug that is hydrolyzed to the active metabolite phenmetrazine, which competes with norepinephrine and dopamine for their presynaptic transporters, thereby blocks the reuptake of these monoamines at the neuronal junctions. As a result, this prolongs activities of dopamine and norepinephrine and leads to central nervous system (CNS) stimulation and metabolic effects, including appetite-suppression, decreased gastric acid secretion and increased blood pressure. ( NCI )]
UMLS (NCI) C0148932 - Organic Chemical
- Pharmacologic Substance
Relation/PAR: PHENDIMETRAZINE
Relation/CHD: PHENDIMETRAZINE TARTRATE 35 MG
PHENDIMETRAZINE TARTRATE 105 MG
PHENDIMETRAZINE TARTRATE 17.5 MG