- 1401. Accidents caused by lifting machines and appliances
- [ ] (UMLS (ICD9CM) C0261705) =Human-caused Phenomenon or Process
| - 1451. ACE-II
- (UMLS (NCI) C0108844) =Therapeutic or Preventive Procedure
|
- 1402. Accidents caused by machinery
- [ ] (UMLS (ICD9CM) C0261712) =Injury or Poisoning
| - 1452. ACEBUTOLOL
- [A synthetic butyranilide derivative with hypotensive and antiarrhythmic activity. Acebutolol acts as a cardioselective beta-adrenergic antagonist with little effect on bronchial receptors and has intrinsic sympathomimetic properties. Having stabilizing and quinidine-like effects on cardiac rhythm, Acebutolol is used in ventricular arrhythmias. Other indications include hypertension, alone or in combinations with other agents. ( NCI )] (UMLS (NCI) C0000946) =Organic Chemical; Pharmacologic Substance
|
- 1403. Accidents caused by metalworking machines
- [ ] (UMLS (ICD9CM) C0261706) =Injury or Poisoning
| - 1453. Aceglatone
- [A derivative of D-glucaro-1, 4-lactone with chemopreventive and anti-tumor activities. The active metabolite of aceglatone, D-glucaro-1,4-Lactone, is an inhibitor of beta-glucuronidase, an enzyme produced by intestinal colonic micro-flora and hydrolyzing glycosidic bonds in glucuronides. One of the key processes in which human body eliminates toxic chemicals as well as hormones (such as estrogen) is by glucuronidation. When beta-glucuronidase deconjugated these glucuronides, it prolongs the stay of the hormone or toxic chemical in the body. Elevated beta-glucuronidase activity has been implicated to be associated with an increased risk for hormone-dependent cancers like breast, prostate, and colon cancers. Thereby, aceglatone may suppress the developments of hormone-dependent cancers mediated through beta-glucuronidase inhibition. ( NCI )] (UMLS (NCI) C0050406) =Organic Chemical ;
|
- 1404. Accidents caused by mining and earth-drilling machinery
- [ ] (UMLS (ICD9CM) C0261704) =Injury or Poisoning
| - 1454. Acepyrene
- [An aromatic hydrocarbon that consists of five fused rings and is formed during the incomplete combustion of organic matter. Cyclopenta[c,d]pyrene is primarily found in gasoline engine exhaust. This substance is used in laboratory research as a mutagen and carcinogen. Cyclopenta[c,d]pyrene is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0056792) =Organic Chemical; Hazardous or Poisonous Substance
|
- 1405. Accidents caused by other hand tools and implements
- [ ] (UMLS (ICD9CM) C0261718) =Injury or Poisoning
| - 1455. Acetabulum
- (UMLS (HL7) C0000962) =Body Part, Organ, or Organ Component ;
|
- 1406. Accidents caused by other powered hand tools
- [ ] (UMLS (ICD9CM) C0261715) =Injury or Poisoning
| - 1456. Acetabulum Fracture
- (UMLS (NCI) C0347804) =Injury or Poisoning
|
- 1407. Accidents caused by other specified machinery
- [ ] (UMLS (ICD9CM) C0261711) =Injury or Poisoning
| - 1457. acetal
- [ ] (UMLS (CSP) C0000967) =Organic Chemical
|
- 1408. Accidents caused by powered household appliances and implements
- [ ] (UMLS (ICD9CM) C0261716) =Injury or Poisoning
| - 1458. acetaldehyde
- [colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors; also an intermediate in the metabolism of alcohol; has a general narcotic action and also causes irritation of mucous membranes. ( CSP )] (UMLS (CSP) C0000966) =Organic Chemical ;
|
- 1409. Accidents caused by powered lawn mower
- [ ] (UMLS (ICD9CM) C0261714) =Injury or Poisoning
| - 1459. acetamide
- [used as a solvent, plasticizer, and a wetting and penetrating agent; formula, C2H5NO. ( CSP )] (UMLS (CSP) C0050423) =Organic Chemical; Pharmacologic Substance =amide;
|
- 1410. Accidents caused by prime movers, except electrical motors
- [ ] (UMLS (ICD9CM) C0261708) =Injury or Poisoning
| - 1460. Acetamide, N,N'-1, 6-hexanediylbis-
- [A hybrid polar-planar compound with potential antineoplastic activity that induces terminal differentiation, inhibits cell growth, and causes apoptosis in several tumor cell lines. Its precise mechanism of action is unknown. (NCI04) ( NCI )] (UMLS (NCI) C0062641) =Organic Chemical; Pharmacologic Substance ;
|
- 1411. ACCIDENTS CAUSED BY SUBMERSION, SUFFOCATION, AND FOREIGN BODIES
- [ ] (UMLS (ICD9CM) C0178358) =Phenomenon or Process
| - 1461. Acetamide, N-((4-aminophenyl)sulfonyl)-N-(3,4-dimethyl-5-isoxazolyl)-
- [An ester of sulfisoxazole, a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial property. Sulfisoxazole acetyl competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death. ( NCI )] (UMLS (NCI) C0081437) =Organic Chemical; Pharmacologic Substance =4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide;
=SULFISOXAZOLE ACETYL 600 MG/5ML;
SULFISOXAZOLE ACETYL 500 MG/5ML;
SULFISOXAZOLE ACETYL 1 GM/5ML;
|
- 1412. Accidents caused by transmission machinery
- [ ] (UMLS (ICD9CM) C0261709) =Injury or Poisoning
| - 1462. Acetamide, N-methyl-N-[4-[(7-methyl-1H-imidazo[4, 5-f]quinolin-9-yl)amino]phenyl]-, monohydrochloride (9CI)
- (UMLS (NCI) C0970589) Acodazole Hydrochloride;
=Organic Chemical; Pharmacologic Substance ;
|
- 1413. Accidents caused by woodworking and forming machines
- [ ] (UMLS (ICD9CM) C0261707) =Human-caused Phenomenon or Process
| - 1463. Acetamide, N-[(methylamino)carbonyl]-N-[[(methylamino)carbonyl]oxy]- (9CI)
- [An agent derived from acetohydroxamic acid with potential antineoplastic activity. Caracemide inhibits ribonuclease reductase, resulting in decreased DNA synthesis and tumor growth; it also inhibits acetylcholinesterase. In vivo, caracemide contributes to the formation of the neurotoxin methyl isocyanate; this effect, along with the agent's acetylcholinesterase activity, may be responsible for the severe central nervous system toxicity observed in clinical trials. (NCI04) ( NCI )] (UMLS (NCI) C0054633) =Organic Chemical; Pharmacologic Substance
|
- 1414. Accidents due to excessive cold
- [ ] (UMLS (ICD9CM) C0261650) =Injury or Poisoning
| - 1464. Acetaminophen #3
- [A synthetic p-aminophenol derivative combined with codeine, anti-inflammatory and analgesic Acetaminophen 3 is used against inflammatory conditions, fever, and pain. Codeine is an opium alkaloid with analgesic properties. The active principal metabolite of phenacetin, Acetaminophen appears to inhibit prostaglandin biosynthesis in the central nervous system and less in peripheral tissues. Equipotent to acetylsalicylic acid, but more toxic, Acetaminophen may cause liver and kidney damage, especially in children. (NCI04) ( NCI )] (UMLS (NCI) C0358847) =Organic Chemical; Pharmacologic Substance
|
- 1415. Accidents due to excessive heat of man-made origin
- [ ] (UMLS (ICD9CM) C0261649) =Human-caused Phenomenon or Process
| - 1465. Acetaminophen Pathway
- [Acetaminophen is one of the world's most commonly used drugs, used for the treatment of pain and fever. Like other NSAIDs (non-steroidal anti-inflammatory drugs), acetaminophen has a unique activity profile based in part on its action at its molecular targets, the cyclooxygenase enzymes that produce prostaglandins responsible for pain, fever and inflammation. Until very recently, only two Cox enzymes, Cox-1 and Cox-2, were known to be targets of NSAIDS. Cox-1 is expressed in a constitutive manner throughout most tissues, and plays an essential role in maintaining the integrity of the stomach mucosal lining. More…
|
- 1416. Accidents due to excessive heat of unspecified origin
- (UMLS (ICD9CM) C0000926) =Injury or Poisoning ;
| - 1466. Acetaminophen/Acetylcysteine
- (UMLS (NCI) C0678074) =Therapeutic or Preventive Procedure ;
|
- 1417. ACCIDENTS DUE TO NATURAL AND ENVIRONMENTAL FACTORS
- [ ] (UMLS (ICD9CM) C0178357) =Injury or Poisoning
| - 1467. Acetaminophen/Acetylcysteine/Carmustine
- (UMLS (NCI) C0678073) =Therapeutic or Preventive Procedure ;
|
- 1418. Accidents involving cable cars not running on rails
- [ ] (UMLS (ICD9CM) C0261369) =Phenomenon or Process
| - 1468. ACETARSONE
- [A pentavalent arsenical compound with antiprotozoal and antihelmintic properties. Although the mechanism of action is not fully known, acetarsone may bind to protein-containing sulfhydryl groups located in the parasite, thereby forming lethal As-S bonds. This may prevent their function and eventually kill the parasite. ( NCI )] (UMLS (NCI) C0050436) =Organic Chemical; Pharmacologic Substance
|
- 1419. Accidents involving other vehicles, not elsewhere classifiable
- [ ] (UMLS (ICD9CM) C0261370) =Phenomenon or Process
| - 1469. acetate
- [salts or esters of acetic acid in which the terminal hydrogen atom is replaced by a metal, for instance copper acetate Cu(CH3COO)2, or where substitution is by a radical, for instance ethyl acetate CH3COOC2H5. ( CSP )] (UMLS (CSP) C0000979) =Organic Chemical; Pharmacologic Substance ;
|
- 1420. Accidents involving powered vehicles used solely within the buildings and premises of industrial or commercial establishment
- [ ] (UMLS (ICD9CM) C0261368) =Phenomenon or Process
| - 1470. acetazolamide
- [carbonic anhydrase inhibitor that is sometimes effective against seizures. ( CSP )] (UMLS (CSP) C0000981) =Organic Chemical; Pharmacologic Substance ;
|
- 1421. acclimatization
- [physiological adaptation of an animal or plant to changes in climate or environment, such as light, temperature, or altitude. ( CSP )] (UMLS (CSP) C0000934) =Organism Function ;
| - 1471. Acetic Acid
- [50% V/V acetic acid in water. Used as a urine preservative ( HL7V3.0 )] (UMLS (HL7) C1550049) =Intellectual Product ;
=MaterialEntityAdditive;
|
- 1422. accommodation
- [An accommodation is a service provided for a Person or other LivingSubject in which a place is provided for the subject to reside for a period of time. Commonly used to track the provision of ward, private and semi-private accommodations for a patient. ( HL7V3.0 )] (UMLS (HL7) C1553447) =Idea or Concept =act;
| - 1472. ACETIC ACID
- [A synthetic carboxylic acid with antibacterial and antifungal properties. Although, the mechanism of action is not fully known, the undissociated acetic acid may enhance lipid solubility allowing increased fatty acid accumulation on the cell membrane or in other cell wall structures. Acetic acid, as a weak acid, can inhibit carbohydrate metabolism resulting in subsequent death of the organism. ( NCI )] (UMLS (NCI) C0000983) =Organic Chemical; Pharmacologic Substance; Indicator, Reagent, or Diagnostic Aid
|
- 1423. Accommodation code
- (UMLS (HL7) C1550405) =Intellectual Product =HL7 Vocabulary Version 2.5;
| - 1473. Acetic Acid Phenyl Ester
- [A drug being studied in the treatment of cancer. ( NCI )] (UMLS (NCI) C0220893) =Organic Chemical; Pharmacologic Substance ;
|
- 1424. Accommodation Requested Not Available
- [Accommodation requested is not available. ( HL7V3.0 )] (UMLS (HL7) C1555448) =Idea or Concept =ActAccommodationReason;
| - 1474. Acetic Acid, Dimethylamide
- (UMLS (NCI) C0058243) =Organic Chemical; Pharmacologic Substance; Indicator, Reagent, or Diagnostic Aid =Acetamides;
Inactive Ingredient Preparations =N,N-DIMETHYLACETAMIDE 60 MG/ML;
|
- 1425. Accommodative component in esotropia
- [ ] (UMLS (ICD9CM) C0155336) =Disease or Syndrome
| - 1475. Acetic Acid, Magnesium Salt
- [The acetate salt form of magnesium. Magnesium is a divalent cation essential for a number of biochemical processes involved in nerve signaling, bone mineralization and muscle contractions. About 350 enzymes involved in glycolysis and the Krebs cycle, formation of cyclic-AMP and ATP, cellular signal transduction and protein and nucleic acid synthesis are dependent on magnesium. ( NCI )] (UMLS (NCI) C0982266) Magnesium Acetate;
MAGNESIUM ACETATE PREPARATION =Organic Chemical; Pharmacologic Substance =[TN406] MAGNESIUM;
TO BE DELETED INGREDIENT PREPARATIONS =MAGNESIUM ACETATE 0.21 GM/L;
MAGNESIUM ACETATE 0.86 GM;
MAGNESIUM ACETATE 21 MG/100ML;
MAGNESIUM ACETATE 32 MG/100ML |
- 1426. accomodation for handicapped
- [ ] (UMLS (CSP) C0598557) =Therapeutic or Preventive Procedure
| - 1476. Acetic Acid, Potassium Salt
- [The acetate salt form of potassium, an essential macromineral. Potassium maintains intracellular tonicity, is required for nerve conduction, cardiac, skeletal and smooth muscle contraction, production of energy, the synthesis of nucleic acids, maintenance of blood pressure and normal renal function. This agent has potential antihypertensive effects and when taken as a nutritional supplement may prevent hypokalemia. ( NCI )] (UMLS (NCI) C0137984) =Organic Chemical; Pharmacologic Substance =acetate;
[TN403] POTASSIUM =POTASSIUM ACETATE 0.2 MEQ/ML;
POTASSIUM ACETATE 2 MEQ/ML;
POTASSIUM ACETATE 4 MEQ/ML;
Potassium Acetate 1.04 MEQ/ML;
POTASSIUM ACETATE 0.69 GM;
POTASSIUM ACETATE 1.28 GM/L;
POTASSIUM ACETATE 1.96 GM;
POTASSIUM ACETATE 128 MG/100ML;
POTASSIUM ACETATE 130 MG/100ML;
POTASSIUM ACETATE 196 MG;
POTASSIUM ACETATE 196 MG/100ML;
POTASSIUM ACETATE 78.5 MG;
|
- 1427. account
- [A financial account established to track the net result of financial acts. ( HL7V3.0 )] (UMLS (HL7) C1551359) =Idea or Concept =act;
| - 1477. Acetic Acid, Sodium Salt
- [The trihydrate sodium salt of acetic acid with alkalinizing, diuretic and electrolyte replacement properties. Following absorption, sodium acetate generates sodium bicarbonate, thereby raising blood and urine pH. In addition, this agent may increase serum sodium concentration. ( NCI )] (UMLS (NCI) C0142785) =Organic Chemical; Pharmacologic Substance ;
=acetate;
[TN404] SODIUM =SODIUM ACETATE, ANHYDROUS;
apraclonidine 10 MG/ML Ophthalmic Solution;
BALNEOL LOTION;
Vincristine 1 MG/ML Injectable Solution;
SODIUM ACETATE 2 MEQ/ML;
SODIUM ACETATE 4 MEQ/ML;
SODIUM ACETATE 5 MEQ/ML;
Sodium Acetate 3.7 MG/ML;
Sodium Acetate 2.2 MG/ML;
SODIUM ACETATE 222 MG;
SODIUM ACETATE 0.015 %;
SODIUM ACETATE 0.11 GM/100ML;
SODIUM ACETATE 0.15 %;
SODIUM ACETATE 0.37 GM;
SODIUM ACETATE 0.38 GM;
SODIUM ACETATE 0.39 %;
SODIUM ACETATE 0.61 GM;
SODIUM ACETATE 0.61 GM/100ML;
SODIUM ACETATE 0.68 GM;
SODIUM ACETATE 10.8 GM/100ML;
SODIUM ACETATE 161 MG/100ML;
SODIUM ACETATE 2.7 GM;
SODIUM ACETATE 204 MG;
SODIUM ACETATE 218 MG;
SODIUM ACETATE 222 MG/100ML;
SODIUM ACETATE 27.2 MG;
SODIUM ACETATE 280 MG/100ML;
SODIUM ACETATE 295 MG/100ML;
SODIUM ACETATE 320 MG/100ML;
SODIUM ACETATE 330 MG/100ML;
SODIUM ACETATE 368 MG/100ML;
SODIUM ACETATE 431 MG;
SODIUM ACETATE 594 MG;
SODIUM ACETATE 594 MG/100ML;
SODIUM ACETATE 6.14 GM/100ML;
SODIUM ACETATE 610 MG/100ML;
SODIUM ACETATE 640 MG/100ML;
SODIUM ACETATE 68 MG;
SODIUM ACETATE 68 MG/100ML;
SODIUM ACETATE 9.25 GM/100ML;
SODIUM ACETATE 9.39 GM/100ML |
- 1428. Account level (default)
- (UMLS (HL7) C1548588) =Idea or Concept =Visit Indicator;
| - 1478. Acetic Acid, Zinc Salt, Dihydrate
- [A zinc salt of acetic acid essential for the synthesis of cholesterol, protein, and fats. Zinc plays an important role in the proper functioning of the immune system. Zinc is required for the enzyme activities necessary for cell division, cell growth, and wound healing as well as the release of vitamin A from the liver. It plays a role in the acuity of the senses of smell and taste and is required to maintain prostate reproductive health and insulin function. Zinc is also involved in the metabolism of carbohydrates. Zinc acetate is administered orally or parenterally as a nutritional supplement. ( NCI )] (UMLS (NCI) C0149368) =Organic Chemical; Pharmacologic Substance =acetate;
[TN405] ZINC;
[DE900] DERMATOLOGICALS, TOPICAL OTHER;
=ZINC ACETATE SPRAY,TOP;
ZINC ACETATE 25 MG;
ZINC ACETATE 50 MG;
ZINC ACETATE 0.1 %;
ZINC ACETATE 1 % |
- 1429. Account number
- (UMLS (HL7) C1549676) =Idea or Concept =Identifier type;
| - 1479. acetoacetate
- [salts and derivatives of acetoacetic acid. ( CSP )] (UMLS (CSP) C0000988) =Organic Chemical
|
- 1430. Account number Creditor
- (UMLS (HL7) C1549677) =Idea or Concept =Identifier type;
| - 1480. acetoacetyl coA thiolase
- [An enzyme that catalyzes the formation of acetoacetyl-CoA from two molecules of ACETYL COA. Some enzymes called thiolase or thiolase-I have referred to this activity or to the activity of ACETYL-COA C-ACYLTRANSFERASE. ( MSH )] (UMLS (CSP) C0001019) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 1431. Account number debitor
- (UMLS (HL7) C1549678) =Idea or Concept =Identifier type;
| - 1481. Acetobacter
- [A species of gram-negative bacteria of the family ACETOBACTERACEAE found in FLOWERS and FRUIT. Cells are ellipsoidal to rod-shaped and straight or slightly curved. ( MSH )] (UMLS (CSP) C0000990) =Bacterium
|
- 1432. Account number query, return matching visit
- (UMLS (HL7) C1546450) =Idea or Concept =What subject filter;
| - 1482. Acetobacter aurantius
- [ ] (UMLS (CSP) C0599234) =Bacterium ;
|
- 1433. account receivable
- [An account for collecting charges, reversals, adjustments and payments, including deductibles, copayments, coinsurance (financial transactions) credited or debited to the account receivable account for a patient's encounter. ( HL7V3.0 )] (UMLS (HL7) C1552602) =Intellectual Product =ActAccountCode;
| - 1483. ACETONURIA
- [ ] (UMLS (ICD9CM) C0162275) =Sign or Symptom ;
|
- 1434. Account Status
- (UMLS (HL7) C0586014) =Functional Concept =HL7 Vocabulary Version 2.5;
| - 1484. Acetophenazine Maleate
- (UMLS (NCI) C0304378) =Organic Chemical; Pharmacologic Substance =acetophenazine;
|
- 1435. ACCRETIONS ON TEETH
- [hard or soft material deposited on a tooth surface, such as dental calculus or plaque and materia alba. ( CSP )] (UMLS (ICD9CM) C0011346) =Disease or Syndrome ;
=Dental Disorder;
dental disorder =dental plaque;
calculi (dental);
dental plaque;
| - 1485. acetophenone
- [ ] (UMLS (CSP) C0050459) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid
|
- 1436. Accrual
- [The process of obtaining subjects for a study. ( NCI )] (UMLS (NCI) C1510756) =Functional Concept
| - 1486. Acetothioamide
- [A synthetic, colorless crystalline solid that is soluble in water and ethanol. Thioacetamide is currently only used as a replacement for hydrogen sulfide in qualitative analysis. When heated to decomposition, it emits toxic fumes of nitrogen oxides and sulfur oxides. The primary routes of potential human exposure to thioacetamide are inhalation and dermal contact. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0039872) =Organic Chemical; Hazardous or Poisonous Substance ;
|
- 1437. Accumbens Nucleus
- [part of the limbic lobe and the hypothalamic-limbic system; collection of pleomorphic cells in the caudal part of the anterior horn of the lateral ventricle, in the region of the olfactory tubercle, lying between the head of the caudate nucleus and the anterior perforated substance; it is part of the ventral striatum, a composite structure considered part of the basal ganglia; involved in narcotic addiction. ( CSP )] (UMLS (NCI) C0028633) =Body Part, Organ, or Organ Component ;
=basal ganglia;
| - 1487. acetrizoate
- [ ] (UMLS (CSP) C0302288) =Organic Chemical; Pharmacologic Substance; Indicator, Reagent, or Diagnostic Aid
|
- 1438. Accuracy of Diagnosis
- [Tthe proportion of all the observations that have been classified correctly by the diagnostic procedures in given population, or using some diagnostic test, or by some medical institution or professional. ( NCI )] (UMLS (NCI) C0598285) =Qualitative Concept
| - 1488. ACETRIZOATE SODIUM
- (UMLS (NCI) C0546847) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid
|
- 1439. AccuSite
- (UMLS (NCI) C0594005) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 1489. acetyl coA
- [participates in biosynthesis of fatty acids and sterols, fatty acid oxidation, metabolism of many amino acids, and acts as a biological acetylating agent. ( CSP )] (UMLS (CSP) C0001026) =Nucleic Acid, Nucleoside, or Nucleotide; Lipid; Biologically Active Substance
|
- 1440. Accutane
- (UMLS (NCI) C0699581) =Organic Chemical; Pharmacologic Substance ;
| - 1490. acetyl coA carboxylase
- [A carboxylating enzyme that catalyzes the conversion of ATP, acetyl-CoA, and HCO3- to ADP, orthophosphate, and malonyl-CoA. It is a biotinyl-protein that also catalyzes transcarboxylation. The plant enzyme also carboxylates propanoyl-CoA and butanoyl-CoA (From Enzyme Nomenclature, 1992) EC 6.4.1.2. ( MSH )] (UMLS (CSP) C0001022) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 1441. Accutane _ Information
- (UMLS (HL7) C1548808) =Health Care Activity =Consent Type;
| - 1491. Acetyl Group Shuttle Pathway
- [Most of the energy derived from the oxidation of glucose is not extracted directly as ATP, but as reduced NADH that transfers high-energy electrons to the electron transport chain in the inner mitochondrial membrane. This NADH comes primarily from the Krebs cycle in the mitochondrial matrix and is therefore directly accessible to electron transport. NADH generated during glycolysis cannot reach the electron transport chain directly however and there is no direct mechanism for the transfer of NADH across the mitochondrial membrane. Instead shuttle mechanisms have evolved to move the energy of reduced NADH across the membrane in the form of other reduced molecules. One shuttle is the glycerophosphate shuttle and another is the malate-aspartate shuttle. The malate-aspartate shuttle occurs in mammalian tissues. First, oxaloacetate on the cytoplasmic side is reduced by NADH, creating malate and NAD+. Malate and the electrons it carries are transported into the mitochondria across the inner mitochondrial membrane, in exchange for alpha-ketoglutarate, which is transported out of the mitochondria. Once inside, the energy in malate is extracted again by reducing NAD+ to make NADH, regenerating oxaloacetate. This NADH is then free to transfer its high energy electrons to the electron transport chain. The oxaloacetate is transaminated with glutamate to make aspartate and alpha-ketoglutarate. Aspartate is returned to the cytosol by the aspartate-glutamate transporter, which moves glutamate into the mitochondria as it transports aspartate out. The overall result is that NADH is transported into the mitochondria, and can be used to generate 3 ATP per every NADH transported in from the cytosol, a very efficient process. (BioCarta) ( NCI )] (UMLS (NCI) C1510758) Shuttle for transfer of acetyl groups from mitochondria to the cytosol;
=Molecular Function ;
|
- 1442. Accutane _ Woman
- (UMLS (HL7) C1548809) =Intellectual Product =Consent Type;
| - 1492. acetylation
- [formation of an acetyl derivative. ( CSP )] (UMLS (CSP) C0001038) =Molecular Function
|
- 1443. ACD
- [A citrate anticoagulant used for the collection and preservation of whole blood. ( NCI )] (UMLS (NCI) C0050552) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid ;
| - 1493. acetylcholine
- [neurotransmitter; in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. ( CSP )] (UMLS (CSP) C0001041) =Organic Chemical; Pharmacologic Substance; Neuroreactive Substance or Biogenic Amine
|
- 1444. ACD
- [The Committee advises and makes recommendations to the Director, NCI, for the oversight and integration of various planning and advisory groups serving the broad programmatic and institutional objectives of the Institute. The Committee serves as the official channel through which the findings and recommendations emerging from these groups are submitted to the NCI. The Committee may consider the reports of the various review groups as informational, advisory, or as recommendations, and shall provide the NCI with assistance in identifying opportunities to be pursued within the areas of cancer research that cut across the intramural and extramural programs. ( NCI )] (UMLS (NCI) C1510822) Advisory Committee to the Director, National Cancer Institute;
Advisory Committee to the Director, NCI;
Committee to the Director, NCI;
=Group | - 1494. acetylcholine acetylhydrolase
- [An enzyme that catalyzes the hydrolysis of ACETYLCHOLINE to CHOLINE and acetate. In the CNS, this enzyme plays a role in the function of peripheral neuromuscular junctions. EC 3.1.1.7. ( MSH )] (UMLS (CSP) C0001044) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 1445. ACD Solution A
- (UMLS (HL7) C0376734) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid ;
=Additive/Preservative;
| - 1495. Acetylcholine Receptor Inducing Activity
- [Neuregulin-1 was first cloned as "heregulin" and "neu differentiation factor" and was initially thought to be a ligand for ErbB2, which is overexpressed in about 25% of women with breast cancer. Neuregulin-1 has also been studied as the "glial growth factor," which acts as a Schwann cell mitogen, and as "ARIA" (acetylcholine receptor inducing activity), a regulator of the expression of acetylcholine receptors. ( NCI )] (UMLS (NCI) C0626201) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 1446. ACD Solution A
- [ACD Solution A of trisodium citrate, 22.0g/L; citric acid, 8.0 g/L; and dextrose 24.5 g/L. Used in Blood banking and histocompatibilty testing ( HL7V3.0 )] (UMLS (HL7) C1550047) =Intellectual Product ;
=MaterialEntityAdditive;
| - 1496. Acetylcholine Receptor, Muscarinic, 4
- [Cholinergic Receptor, Muscarinic 4, encoded by the human CHRM4 gene, is a G protein-coupled receptor. The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and postassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. (From LocusLink and NCI) ( NCI )] (UMLS (NCI) C1334833) Cholinergic Receptor, Muscarinic 4;
Cholinergic Receptor, Muscarinic, 4;
CHRM4;
CHRM4 Protein;
HM4;
Muscarinic Acetylcholine Receptor M4 =Amino Acid, Peptide, or Protein; Receptor |
- 1447. ACD Solution B
- (UMLS (HL7) C1550048) =Indicator, Reagent, or Diagnostic Aid ;
=Additive/Preservative;
| - 1497. Acetylcholinesterase Inhibitor
- (UMLS (NCI) C0001046) =Pharmacologic Substance
|
- 1448. ACD Solution B
- [ACD Solution B of trisodium citrate, 13.2g/L; citric acid, 4.8 g/L; and dextrose 14.7 g/L. Used in Blood banking and histocompatibilty testing. ( HL7V3.0 )] (UMLS (HL7) C1561453) =Intellectual Product =MaterialEntityAdditive;
| - 1498. acetylcysteine
- [N-acetyl derivative of cysteine; used as a mucolytic agent to reduce the viscosity of mucous secretions. ( CSP )] (UMLS (CSP) C0001047) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
|
- 1449. ACE
- [ ] (UMLS (CSP) C0050385) =Therapeutic or Preventive Procedure ;
| - 1499. ACETYLDIGITOXIN
- (UMLS (NCI) C0520442) =Steroid; Carbohydrate; Pharmacologic Substance
|
- 1450. ACE
- (UMLS (NCI) C0279078) =Therapeutic or Preventive Procedure
| - 1500. acetylene
- [ ] (UMLS (CSP) C0001052) =Organic Chemical
|
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