- 1. (+)-Aldosterone
- [hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium. ( CSP )] (UMLS (NCI) C0002006) =Steroid; Pharmacologic Substance; Hormone
| - 51. 2alpha,3beta,6beta,23-Tetrahydroxyurs-12-en-28-oic Acid
- (UMLS (NCI) C0065501) =Organic Chemical; Pharmacologic Substance ;
|
- 2. (+)-alpha-Tocopherol
- [A naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties. Considered essential for the stabilization of biological membranes (especially those with high amounts of polyunsaturated fatty acids), d-alpha-Tocopherol is a potent peroxyl radical scavenger and inhibits noncompetitively cyclooxygenase activity in many tissues, resulting in a decrease in prostaglandin production. Vitamin E also inhibits angiogenesis and tumor dormancy through suppressing vascular endothelial growth factor (VEGF) gene transcription. (NCI04) ( NCI )] (UMLS (NCI) C0969677) .alpha. Tocopherol;
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol;
alpha Tocopherol;
ALPHA-TOCOPHEROL;
d-Alpha-Tocopherol;
Tocopherol-Alpha;
Tocopherol-D-Alpha;
=Lipid; Pharmacologic Substance; Vitamin | - 52. 3.Alpha,4.Beta, 15-triol, 12, 13-epoxy-,4, 15-diacetate (8CI)
- [trichothecene mycotoxin produced by species of Fusarium that contaminate grain and other foodstuffs, causing fusariotoxicosis and hemorrhaging in livestock. ( CSP )] (UMLS (NCI) C0057671) =Organic Chemical; Pharmacologic Substance ;
=Fungal Toxin;
sesquiterpene |
- 3. (+)-alpha-Tocopherol Acetate
- [The acetate ester of a fat-soluble vitamin with potent antioxidant properties. Considered essential for the stabilization of biological membranes (especially those with high amounts of polyunsaturated fatty acid), vitamin E is a generic name for a group of compounds known as tocopherols and tocotrienols (tocols). This agent is a potent peroxyl radical scavenger and inhibits noncompetitively cyclooxygenase activity in many tissues, resulting in a decrease in prostaglandin production. Vitamin E also inhibits angiogenesis and tumor dormancy through suppressing vascular endothelial growth factor (VEGF) gene transcription. (NCI04) ( NCI )] (UMLS (NCI) C0078373) =Organic Chemical; Pharmacologic Substance; Vitamin =(+/-)-alpha-Tocopherol;
(+)-alpha-Tocopherol Acetate;
Unclassified Ingredient Preparations;
=(+)-alpha-Tocopherol Acetate;
THICKENUP POWDER;
TOCOPHERYL ACETATE,ALPHA 15 MG;
TOCOPHERYL ACETATE,ALPHA 30 UNT;
OMEGA-3 (N-3) POLYUNSATURATED FATTY ACIDS 1GM CAP;
TOCOPHERYL ACETATE,D-ALPHA 30 MG;
VITAMIN E ACETATE 30 IU;
VITAMIN E ACETATE 30 UNT;
| - 53. 4,5-alpha-Epoxy-3,14-dihydroxy-17-methylmorphinan-6-one Hydrochloride
- [The hydrochloride salt form of oxymorphone, a semisynthetic opioid with a potent analgesic property. Oxymorphone hydrochloride binds to and activates opiate receptors, specifically mu-receptors, in the central nervous system (CNS). This results in sedation, analgesia, decreased gastrointestinal motility, and respiratory depression. ( NCI )] (UMLS (NCI) C0282275) =Organic Chemical; Pharmacologic Substance =OXYMORPHONE;
=OXYMORPHONE HYDROCHLORIDE 1 MG/ML;
OXYMORPHONE HYDROCHLORIDE 1.5 MG/ML;
OXYMORPHONE HYDROCHLORIDE 5 MG |
- 4. (+-)-alpha-((tert-Butylamino)methyl)-3,5-dihydroxybenzyl Alcohol Sulfate(2:1)(salt)
- [The sulfate salt form of terbutaline, an ethanolamine derivative with bronchodilating and tocolytic properties. Terbutaline sulfate selectively binds to and activates beta-2 adrenergic receptors, leading to intracellular adenyl cyclase activation via a trimeric G protein and subsequent increase in cyclic cAMP production. Increased cAMP levels result in relaxation of bronchial and vascular smooth muscle mediated through the activation of protein kinase A (PKA), which phosphorylates proteins in control of muscle tone. cAMP also inhibits calcium ion release from intracellular stores, reduces calcium entry into cells and induces the sequestration of intracellular calcium all of which aids the relaxation of airway muscles. Terbutaline sulfate also increases mucociliary clearance and reduces release of inflammatory cell mediators. ( NCI )] (UMLS (NCI) C0039543) =Organic Chemical; Pharmacologic Substance ;
=TERBUTALINE;
=TERBUTALINE SULFATE 1 MG/ML;
TERBUTALINE SULFATE 2.5 MG;
TERBUTALINE SULFATE 5 MG | - 54. 4,5alpha-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one Hydrochloride
- [The hydrochloride salt of oxycodone, a methylether of oxymorphone and semisynthetic opioid agonist with analgesic and antitussive properties. Oxycodone binds to mu-receptors in the central nervous system (CNS), thereby mimicking the effects of endogenous opiates. In addition to analgesia and a depressive effect on the cough center in the medulla, this agent may cause euphoria, anxiolysis, miosis, sedation, physical dependence, constipation, and respiratory depression, depending on dosage and variations in individual metabolism. ( NCI )] (UMLS (NCI) C0282274) =Organic Chemical; Pharmacologic Substance =4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one;
=OXYCODONE HYDROCHLORIDE 5 MG;
OXYCODONE HYDROCHLORIDE 20 MG/ML;
OXYCODONE HYDROCHLORIDE 5 MG/5ML;
OXYCODONE HYDROCHLORIDE 20 MG;
OXYCODONE HYDROCHLORIDE 80 MG;
OXYCODONE HYDROCHLORIDE 160 MG;
OXYCODONE HYDROCHLORIDE 10 MG;
OXYCODONE HYDROCHLORIDE 40 MG;
OXYCODONE HYDROCHLORIDE 15 MG;
OXYCODONE HYDROCHLORIDE 2.5 MG;
OXYCODONE HYDROCHLORIDE 7.5 MG;
OXYCODONE HYDROCHLORIDE 30 MG;
OXYCODONE HYDROCHLORIDE 2.25 MG;
OXYCODONE HYDROCHLORIDE 4.5 MG;
|
- 5. (+/-)-alpha-Tocopherol
- [A substance used in cancer prevention. It belongs to the family of drugs called tocopherols. ( NCI )] (UMLS (NCI) C0042874) =Lipid; Pharmacologic Substance; Vitamin =benzopyran;
[DE350] EMOLLIENTS;
(+/-)-alpha-Tocopherol;
[VT000] VITAMINS =(+)-alpha-Tocopherol Acetate;
VITAMIN E OIL;
TOCOPHERYL ACID SUCCINATE,D-ALPHA;
TOCOPHEROL,DL-ALPHA;
(+)-alpha-Tocopherol Acetate;
AMINOBENZOIC ACID LOTION (ML);
PEPTAMEN LIQUID UNFLAVORED,250ML;
PEPTAMEN LIQUID VANILLA,250ML;
ALOE VERA/VITAMIN E OIL,TOP;
CARA-KLENZ,SKIN & WOUND CLEANSER;
CARRINGTON INCONTINENCE SKIN KIT;
ISOCAL HN (VANILLA) LIQUID,240ML;
ISOCAL LIQUID,CAN,240ML;
ISOCAL LIQUID,CAN,360ML; More… | - 55. 4-(all-trans-retino-yl)aminophenol
- [N-(4-hydroxyphenyl)retinamide; a synthetic retinoid used orally as a chemopreventive agent against prostate cancer in men and in women at risk of developing breast cancer; also effective as an antineoplastic agent. ( CSP )] (UMLS (NCI) C0060197) =Organic Chemical; Pharmacologic Substance =[AN000] ANTINEOPLASTICS;
Retinoic Acid Agent |
- 6. (-)-alpha-(1-Aminoethyl)-3,4-dihydroxybenzyl Alcohol
- [The levoisomer of nordefrin, a synthetic catecholamine and norepinephrine derivative with sympathomimetic and antihypertensive effects. Levonordefrin's antihypertensive effect is exerted through activation of alpha 2-adrenergic receptors in the cardiovascular control center of the CNS thereby suppressing the sympathetic output from the brain and subsequently lowering blood pressure. Levonordefrin binds to and activates peripheral alpha 2- adrenergic receptors, thereby causing vasoconstriction. ( NCI )] (UMLS (NCI) C0520472) =Organic Chemical; Pharmacologic Substance ;
=Nordefrin;
[DE700] LOCAL ANESTHETICS, TOPICAL =LEVONORDEFRIN 1:20000 | - 56. 5 Alpha-Reductase Inhibitor
- [Substances that inhibit 5-alpha-Reductase, an enzyme that metabolizes testosterone to dihydrotestosterone, and can reduce prostate size. ( NCI )] (UMLS (NCI) C1318898) 5-alpha Reductase Inhibitors;
=Pharmacologic Substance ;
=enzyme inhibitor;
|
- 7. (1 Alpha,11 alpha)-11-(acetyloxy)-1-(methoxymethyl)-2-oxaandrosta-5,8-dieno(6,5,4-bc)furan- 3,7,17-trione
- [A potent fungal metabolite isolated from Penicillium wortmannin that selectively inhibits phosphatidylinositol 3-kinase and affects the signal transduction pathway. (NCI) ( NCI )] (UMLS (NCI) C0078517) =Steroid; Pharmacologic Substance; Biologically Active Substance
| - 57. 5-ALA
- [A drug used in photodynamic therapy that is absorbed by tumor cells; when exposed to light, it becomes active and kills the cancer cells. ( NCI )] (UMLS (NCI) C0002563) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Biologically Active Substance
|
- 8. (11alpha,13E)-(+-)-11,16-Dihydroxy-16-methyl-9-oxo-prost-13-en-1-oic Acid Methyl Ester
- [A radioprotective agent that belongs to the family of drugs called prostaglandins. ( NCI )] (UMLS (NCI) C0085174) =Eicosanoid; Pharmacologic Substance =Prostaglandins E, Synthetic;
[GA309] ANTIULCER AGENTS, OTHER =Misoprostol 0.2 MG;
Misoprostol 0.1 MG;
| - 58. 5alpha,7alpha(S))-alpha-tert-Butyl-17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-6,14-ethenomorphinan-7-methanol Hydrochloride
- [The hydrochloride salt form of buprenorphine, a synthetic phenanthrene with narcotic analgesic activity. Buprenorphine hydrochloride is a partial agonist at the mu-opioid receptor and an antagonist at the kapa-opioid receptor in the central nervous system. However, under the conditions of recommended use it behaves as a classic mu-opioid agonist, mimicking the actions of endogenous peptides at CNS opioid receptors. The agonist action results in a raised pain threshold and increased tolerance to pain. However, it also causes sedation, physical dependence, and respiratory depressant effects and decreases heart rate and blood pressure. ( NCI )] (UMLS (NCI) C0701445) =Organic Chemical; Pharmacologic Substance ;
=buprenorphine;
=BUPRENORPHINE HYDROCHLORIDE 0.3 MG/ML;
BUPRENORPHINE HYDROCHLORIDE 2 MG;
BUPRENORPHINE HYDROCHLORIDE 8 MG |
- 9. (11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic Acid
- [The naturally occuring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Alprostadil is a potent vasodilator agent that increases peripheral blood flow, inhibits platelet aggregation, and induces bronchodilation. Used in the treatment of erectile dysfunction, this agent produces corporal smooth muscle relaxation by binding to PGE receptors, resulting in the activation of adenylate cyclase and the subsequent accumulation of 3'5'-cAMP. ( NCI )] (UMLS (NCI) C0002335) =Eicosanoid; Pharmacologic Substance ;
| - 59. 5alphaR
- [ ] (UMLS (CSP) C0599937) =Amino Acid, Peptide, or Protein; Enzyme
|
- 10. (17-alpha)-13-Ethyl-17-hydroxy-11-methylene-18,19-dinorpregn-4-en-20-yn-3-one
- [A synthetic form of the naturally occurring female sex hormone progesterone. Etonogestrel binds to the cytoplasmic progesterone receptors in the reproductive system and subsequently activates progesterone receptor mediated gene expression. As a result of the negative feedback mechanism, luteinizing hormone (LH) release is inhibited, which leads to an inhibition of ovulation and an alteration in the cervical mucus and endometrium. ( NCI )] (UMLS (NCI) C0047683) =Steroid; Pharmacologic Substance ;
=[HS200] CONTRACEPTIVES, SYSTEMIC;
Unclassified Ingredients =ETONOGESTREL 0.12 MG | - 60. 6alpha,9-Difluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-Diacetate
- [The acetate salt form of diflorasone, a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by diffusion across the cell membrane and binds to the glucocorticoid receptor (GR) in the cytoplasm. The receptor complex subsequently translocates to the nucleus and activates or represses genes by interacting with short, palindromic DNA sequences called glucocorticoid response element (GRE). Gene activation leads to the exertion of anti-inflammatory effects, e.g. upregulation of IkappaB, while gene repression inhibits production of pro-inflammatory cytokines such as interleukin-1 (IL-1), IL-2 and IL-6, thereby preventing activation of cytotoxic T-lymphocytes. ( NCI )] (UMLS (NCI) C0057992) =Steroid; Pharmacologic Substance ;
=BETAMETHASONE;
DIFLORASONE =DIFLORASONE DIACETATE 0.05 %;
|
- 11. (17Alpha)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one
- [The levorotatory form of norgestrel and synthetic progestogen with progestational and androgenic activity. Levonorgestrel binds to the progesterone receptor in the nucleus of target cells, thereby stimulating the resulting hormone-receptor complex, initiating transcription, and increasing the synthesis of certain proteins. This results in a suppression of luteinizing hormone (LH) activity and an inhibition of ovulation, as well as an alteration in the cervical mucus and endometrium. ( NCI )] (UMLS (NCI) C0023566) =Steroid; Pharmacologic Substance; Hormone ;
=female antifertility drug;
(+/-)-13-Ethyl-17alpha-hydroxy-18,19-dinorpregn-4-en-20-yne-3-one;
[HS800] PROGESTINS;
[HS200] CONTRACEPTIVES, SYSTEMIC =LEVONORGESTREL 0.05 MG;
LEVONORGESTREL 0.15 MG;
LEVONORGESTREL 0.25 MG;
LEVONORGESTREL 0.1 MG;
LEVONORGESTREL 0.75 MG;
LEVONORGESTREL 36 MG;
LEVONORGESTREL 0.05-0.125 MG;
LEVONORGESTREL 52 MG;
| - 61. 6alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregn-4-ene-3,20-dione, cyclic 16,17-acetal with Acetone
- [A synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Flurandrenolide exerts its effects by interacting with specific cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions. ( NCI )] (UMLS (NCI) C0016374) =Steroid; Pharmacologic Substance; Hormone =Pregnenediones;
Steroids, Fluorinated;
[DE200] ANTI-INFLAMMATORY, TOPICAL;
=FLURANDRENOLIDE 4 MCG/SQC;
FLURANDRENOLIDE 0.05 %;
FLURANDRENOLIDE 0.025 %;
|
- 12. (17alpha)-19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol
- [semisynthetic alkylated estradiol with a 17-alpha-ethinyl substitution; has high estrogenic potency when administered orally, and is often used as the estrogenic component in oral contraceptives. ( CSP )] (UMLS (NCI) C0015011) =Steroid; Pharmacologic Substance; Hormone =[HS300] ESTROGENS;
estrogen analog;
Norpregnatrienes;
=(17alpha)-3-Methoxy-19-norpregna-1,3,5(10)-trien-20-yn-17-ol;
QUINESTROL;
ETHINYL ESTRADIOL 0.03 MG;
ETHINYL ESTRADIOL 0.5 MG;
ETHINYL ESTRADIOL 0.02 MG;
ETHINYL ESTRADIOL 0.05 MG;
ETHINYL ESTRADIOL 0.035 MG;
ETHINYL ESTRADIOL 0.01 MG;
ETHINYL ESTRADIOL 0.025 MG;
ETHINYL ESTRADIOL 0-35 MCG;
ETHINYL ESTRADIOL 0.015 MG;
ETHINYL ESTRADIOL 0.03-0.04 MG;
ETHINYL ESTRADIOL 0.25 MG;
{7 (Ethinyl Estradiol 0.035 MG / Norethindrone 0.5 MG Oral Tablet) / 7 (Ethinyl Estradiol 0.035 MG / Norethindrone 0.75 MG Oral Tablet) / 7 (Ethinyl Estradiol 0.035 MG / Norethindrone 1 MG Oral Tablet) / 7 (Inert Ingredients 1 MG Oral Tablet) } Pack [Necon 7/7/7 28 Day];
{21 (Ethinyl Estradiol 0.03 MG / Norgestrel 0.3 MG Oral Tablet) / 7 (Inert Ingredients 1 MG Oral Tablet) } Pack [Lo/Ovral 28 Day] | - 62. 6alpha-Methyl-11-oxoprogesterone
- [The basic, partial chemical structure of corticosteroid hormones such as cortisone and aldosterone. (NCI04) ( NCI )] (UMLS (NCI) C0099478) =Organic Chemical; Pharmacologic Substance ;
|
- 13. (17alpha)-3-Methoxy-19-norpregna-1,3,5(10)-trien-20-yn-17-ol
- [A semisynthetic estrogen. Metabolized by the liver to ethynyl estradiol, mestranol serves as the estrogen component in several combination oral contraceptives. (NCI04) ( NCI )] (UMLS (NCI) C0025506) =Steroid; Pharmacologic Substance =[HS300] ESTROGENS;
(17alpha)-19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol =MESTRANOL 0.1 MG;
MESTRANOL 0.15 MG;
MESTRANOL 0.05 MG;
MESTRANOL 50 MCG | - 63. 7-(alpha-(4-Pyridylthio)acetamido)cephalosporanic acid sodium salt
- [The sodium salt form of cephapirin, a semi-synthetic, broad-spectrum, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephapirin sodium inhibits bacterial cell wall synthesis by inhibiting the final transpeptidation step of peptidoglycan synthesis and subsequent cross-linking of peptidoglycan units. This results in a reduction of cell wall stability and leads to cell lysis. ( NCI )] (UMLS (NCI) C0085905) =Organic Chemical; Antibiotic =7-(D-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)-oct-2-ene-2-caboxylic Acid;
=cephapirin 1 gm injectable powder for injection |
- 14. (17alpha)-Pregna-2,4-dien-20-yno[2,3-d]isoxazol-17-ol
- [A synthetic hormone that belongs to the family of drugs called androgens and is used to treat endometriosis. It is being evaluated in the treatment of endometrial cancer. ( NCI )] (UMLS (NCI) C0010961) =Steroid; Pharmacologic Substance =Pregnadienes;
[HS100] ANDROGENS/ANABOLICS =DANAZOL 100 MG;
DANAZOL 50 MG;
DANAZOL 200 MG;
| - 64. 7-Allyl-8-oxoguanosine
- [A guanine ribonucleotide derivative with immunostimulatory and immunomodulatory activity. Loxoribine undergoes facilitated transport across the plasma membrane into the cytoplasmic compartment of the cell and acts intracellularly, bypassing the biochemical steps involved in the membrane signal transduction pathway used by Ag or anti-IgM Abs to activate B cells. This agent activates the Toll-like receptor 7 (TLR7), a member of the TLR family of pathogen-associated molecular pattern recognition receptors thereby activating the innate immune system. This activation requires endosomal maturation and recognition is restricted to TLR7. As a result, loxoribine induces cycling B cells to proliferate and differentiate non-specifically and recruit antigen-reactive B cells to undergo differentiation to antibody production, markedly amplifying the underlying response in the process. ( NCI )] (UMLS (NCI) C0209660) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance; Immunologic Factor
|
- 15. (1alpha,2alpha,3beta,4alpha,5alpha,6beta)1,2,3,4,5,6-Hexachlorocyclohexane
- [gamma isomer of benzene hexachloride, a carcinogenic insecticide more potent than DDT (chlorophenothane); it is used to kill lice and mites, applied topically to the skin. ( CSP )] (UMLS (NCI) C0005038) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance
| - 65. 7alpha hydroxylase
- [nonEC. ( CSP )] (UMLS (CSP) C0599930) =Amino Acid, Peptide, or Protein; Enzyme =Oxygenase;
|
- 16. (1alpha,3beta,5Z,7E)-9,10-Secocholesta-3,7,10(19),16-tetraene-1,3,25-triol
- (UMLS (NCI) C0255545) =Steroid; Pharmacologic Substance ;
| - 66. 9,11alpha-Epoxy-17-hydroxy-3-oxo-17alpha-pregn-4-ene-7alpha,21-dicarboxylic acid, gamma-lactone, Methyl Ester
- [A selective aldosterone receptor antagonist. Eplerenone binds to the mineralocorticoid receptor and blocks the binding of aldosterone, thereby decreasing sodium resorption and subsequently increasing water outflow. This leads to a decrease in blood pressure. Eplerone is used in the treatment of hypertension and congestive heart failure. ( NCI )] (UMLS (NCI) C0961485) Eplerenone;
EPLERENONE PREPARATION;
=Steroid; Pharmacologic Substance =[CV704] POTASSIUM-SPARING/COMBINATIONS DIURETICS;
Unclassified Ingredients =EPLERENONE 25 MG;
EPLERENONE 50 MG;
EPLERENONE 100 MG;
|
- 17. (1alpha,3beta,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol
- [most biologically active metabolite of cholecalciferol; acts via a DNA-binding steroid receptor which induces transcription of calcium transport factors in gut; USP drug (calcitriol) is given as an antihypocalcemic. ( CSP )] (UMLS (NCI) C0006674) =Steroid; Pharmacologic Substance; Hormone; Vitamin =(1alpha,3beta,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol;
Dihydroxycholecalciferols;
[VT500] VITAMIN D;
steroid hormone =Calcipotriene;
(1alpha,3beta,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol;
Calcitriol 0.00025 MG;
Calcitriol 0.0005 MG;
Calcitriol 0.001 MG/ML;
Calcitriol 0.002 MG/ML | - 67. 9-alpha-Fluoro-11-beta,21-dihydroxy-16-alpha-isopropylidenedioxy-1,4-pregnadiene,3,20-dione
- [The acetonide salt form of triamcinolone, a synthetic glucocorticosteroid with immunosuppressive and anti-inflammatory activity. Triamcinolone acetonide binds to specific cytosolic glucocorticoid receptors and subsequently interacts with glucocorticoid receptor response element on DNA and alters gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. ( NCI )] (UMLS (NCI) C0040866) =Steroid; Pharmacologic Substance ;
=(11beta,16alpha)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione;
[DE200] ANTI-INFLAMMATORY, TOPICAL;
[NT200] ANTI-INFLAMMATORIES, NASAL;
[OR900] DENTAL AND ORAL AGENTS, TOPICAL OTHER;
[RE101] ANTI-INFLAMMATORIES, INHALATION;
=(11beta,16alpha)-21-(3,3-Dimethyl-1-oxobutoxy)-9-fluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))pregna-1,4-diene-3,20-dione;
TRIAMCINOLONE ACETONIDE PWDR;
TRIAMCINOLONE ACETONIDE 0.1 %;
TRIAMCINOLONE ACETONIDE 40 MG/ML;
TRIAMCINOLONE ACETONIDE 100 MCG/ACTUAT;
TRIAMCINOLONE ACETONIDE 10 MG/ML;
TRIAMCINOLONE ACETONIDE 55 MCG/ACTUAT;
TRIAMCINOLONE ACETONIDE 2.5 MG/GM;
TRIAMCINOLONE ACETONIDE 50 MCG/ACTUAT;
TRIAMCINOLONE ACETONIDE 3 MG/ML;
TRIAMCINOLONE ACETONIDE 3.3 MG/50GM;
TRIAMCINOLONE ACETONIDE 0.025 %;
TRIAMCINOLONE ACETONIDE 0.147 MG/GM;
TRIAMCINOLONE ACETONIDE 0.5 %;
TRIAMCINOLONE ACETONIDE 1 MG/GM |
- 18. (1alpha,3beta,5Z,7E)-9,10-Secostigmasta-5,7,10(19)-triene-1,3-diol
- (UMLS (NCI) C0534957) =Steroid ;
| - 68. AL
- [A state in the southeast United States. Its capital is Montgomery. ( NCI )] (UMLS (NCI) C0001895) =Geographic Area ;
◊ [A country in Southeastern Europe, bordering the Adriatic Sea and Ionian Sea, between Greece and Serbia and Montenegro. (NCI) ( NCI )] (UMLS (NCI) C0001909) Geographic Area ; |
- 19. (1alpha,3beta,5Z,7E,22E)-9,10-Secoergosta-5,7,10(19),22-tetraene-1,3-diol
- [A substance that is being studied in the prevention of recurrent prostate cancer. It belongs to the family of drugs called vitamin D analogs. ( NCI )] (UMLS (NCI) C0043668) =Steroid; Pharmacologic Substance; Vitamin =Ergocalciferols;
[VT509] VITAMIN D, OTHER =Doxercalciferol 0.002 MG/ML;
DOXERCALCIFEROL 0.0025 MG;
| - 69. Al element
- [extremely light, whitish, lustrous, metallic element, obtainable from bauxite or clay; atomic number, 13. ( CSP )] (UMLS (CSP) C0002367) =Element, Ion, or Isotope
|
- 20. (2alpha,3beta)-2,3,23-Trihydroxyurs-12-en-28-oic acid, O-6-deoxy-alpha-L-mannopyranosyl-(1--4)--beta-D-glucopyranosyl-(1--6)-O-beta-D-glucopyranosyl Ester
- (UMLS (NCI) C0052506) =Organic Chemical; Pharmacologic Substance
| - 70. AL-6221
- (UMLS (NCI) C1098436) =Organic Chemical; Pharmacologic Substance ;
|
- 21. (3alpha,5beta,7beta)-3,7-Dihydroxycholan-24-oic acid
- [A synthetically-derived form of ursodiol, a bile acid produced by the liver and secreted and stored in the gallbladder. Also produced by the Chinese black bear liver, ursodiol has been used in the treatment of liver disease for centuries. This agent dissolves or prevents cholesterol gallstones by blocking hepatic cholesterol production and decreasing bile cholesterol. Ursodiol also reduces the absorption of cholesterol from the intestinal tract. ( NCI )] (UMLS (NCI) C0042105) =Steroid; Pharmacologic Substance; Biologically Active Substance =Deoxycholic Acid;
(3alpha,5beta,7beta)-3,7-Dihydroxycholan-24-oic acid;
[GA900] GASTRIC MEDICATIONS, OTHER;
=(3alpha,5beta,7beta)-3,7-Dihydroxycholan-24-oic acid;
URSODIOL 250 MG;
Ursodeoxycholate 300 MG | - 71. AL721
- [A mixture of neutral lipids (70%), phosphatidylcholine (20%) and phosphatidylethanolamine (10%), AL721 removes cholesterol from outer cell membranes, increases membrane fluidity, and impairs virus attachment to cell receptors. AL721 is potentially useful (and in study) for diseases where membrane fluidity plays a role (cancers, cystic fibrosis). (NCI04) ( NCI )] (UMLS (NCI) C0051047) =Organic Chemical; Pharmacologic Substance
|
- 22. (4Alpha,5alpha,17beta)-4,5-epoxy-3,17-dihydroxyandrost-2-ene-2-carbonitrile
- [A synthetic derivative of androstane with adrenocortical suppressive properties. Trilostane reversibly inhibits 3 beta-hydroxysteroid dehydrogenase delta 5-4 isomerase in the adrenal cortex, resulting in the decreased synthesis of mineralocorticoids and glucocorticoids and the decreased conversion of pregnenolone to progesterone. (NCI04) ( NCI )] (UMLS (NCI) C0077144) =Steroid; Pharmacologic Substance =Stanolone;
[HS900] HORMONES/SYNTHETICS/MODIFIERS, OTHER;
TO BE DELETED INGREDIENT PREPARATIONS;
=TRILOSTANE 60 MG;
TRILOSTANE 30 MG;
| - 72. Alabama
- (UMLS (HL7) C1551894) =Language =CentralMuskogean;
|
- 23. (5alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one Hydrochloride
- [The hydrochloride salt form of naltrexone, a noroxymorphone derivative with competitive opioid antagonistic property. Naltrexone reverses the effects of opioid analgesics by binding to the various opioid receptors in the central nervous system, including the mu-, kappa- and gamma-opioid receptors. This leads to an inhibition of the typical actions of opioid analgesics, including analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia, and physical dependence. Naltrexone is longer-acting and more potent compared to naloxone. ( NCI )] (UMLS (NCI) C0355800) =Organic Chemical; Pharmacologic Substance =NALTREXONE;
=NALTREXONE HYDROCHLORIDE 50 MG | - 73. Alabama-Coushatta Tribes of Texas
- (UMLS (HL7) C1554222) =Population Group =NativeEntityContiguous;
|
- 24. (5alpha,17beta)-17-Hydroxyandrostan-3-one
- [potent androgenic metabolite of testosterone; dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone; unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure androgenic steroid. ( CSP )] (UMLS (NCI) C0038148) =Steroid; Pharmacologic Substance; Hormone =androgen;
Androstanols =(4Alpha,5alpha,17beta)-4,5-epoxy-3,17-dihydroxyandrost-2-ene-2-carbonitrile | - 74. Alabama-Quassarte Tribal Town, Oklahoma
- (UMLS (HL7) C1554223) =Population Group =NativeEntityContiguous;
|
- 25. (5alpha,17beta)-N-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide
- [orally active testosterone 5-alpha reductase inhibitor, used as an alternative to surgery for treatment of benign prostatic hyperplasia. ( CSP )] (UMLS (NCI) C0060389) =Steroid; Pharmacologic Substance ;
=Androstenes;
[AN000] ANTINEOPLASTICS;
Azasteroids;
enzyme inhibitor;
[HS900] HORMONES/SYNTHETICS/MODIFIERS, OTHER;
=FINASTERIDE 1 MG;
FINASTERIDE 5 MG | - 75. Alagille syndrome
- [autosomal dominant mutation involving chromosome 20; characterized by the almost normal liver that has few or no intrahepatic bile ducts; other extrahepatic malformations include those in the heart, the eyes, the vertebral column, and the facies; major clinical features include jaundice, and congenital heart disease with peripheral pulmonary stenosis. ( CSP )] (UMLS (CSP) C0085280) =Congenital Abnormality =Abnormalities, Multiple;
bile obstruction;
Cholestasis, Intrahepatic;
Genetic Condition;
syndrome;
congenital heart disorder |
- 26. (5alpha,6alpha)-17-(Cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol Hydrochloride
- [The hydrochloride salt form of nalbuphine, a synthetic phenanthrene opioid with opiate agonist and antagonist effects, used to treat moderate to severe pain and provide preoperative and postoperative analgesia and sedation. Nalbuphine hydrochloride binds to kappa-, mu- and delta-opioid receptors but not to sigma-opioid receptors. This opioid exerts its analgesic actions primarily through kappa-opioid-receptor agonism and partially through mu-opioid receptor agonism. ( NCI )] (UMLS (NCI) C0600099) =Organic Chemical; Pharmacologic Substance =NALBUPHINE;
=NALBUPHINE HYDROCHLORIDE 20 MG/ML;
NALBUPHINE HYDROCHLORIDE 1.5 MG/ML;
NALBUPHINE HYDROCHLORIDE 10 MG/ML | - 76. alanine
- [non-essential amino acid that occurs in high levels in its free state in plasma; it is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and the central nervous system. ( CSP )] (UMLS (CSP) C0001898) =Amino Acid, Peptide, or Protein; Biologically Active Substance
|
- 27. (6alpha)-17-(Acetyloxy)-6-methylpregn-4-ene-3,20-dione
- [A synthetic, acetate derivative of the sex hormone progesterone. Medroxyprogesterone 17-acetate (NCI04) ( NCI )] (UMLS (NCI) C0065864) =Steroid; Pharmacologic Substance; Hormone =(6Alpha)-17-hydroxy-6-methylpregn-4-ene-3,20-dione;
=MEDROXYPROGESTERONE ACETATE 14 TABS X 5 MG;
MEDROXYPROGESTERONE ACETATE DAY15-28 X 5 MG;
MEDROXYPROGESTERONE ACETATE 5 MG;
MEDROXYPROGESTERONE ACETATE 2.5 MG;
MEDROXYPROGESTERONE ACETATE 100 MG/ML;
MEDROXYPROGESTERONE ACETATE 10 MG;
MEDROXYPROGESTERONE ACETATE 25 MG;
MEDROXYPROGESTERONE ACETATE 400 MG/ML;
MEDROXYPROGESTERONE ACETATE 150 MG/ML;
| - 77. Alanine Aminotransferase
- [A measurement of the alanine aminotransferase in a biological specimen. ( NCI )] (UMLS (NCI) C0201836) =Laboratory Procedure
|
- 28. (6Alpha)-17-hydroxy-6-methylpregn-4-ene-3,20-dione
- [synthetic progestin derived from 17-hydroxyprogesterone; a long-acting contraceptive that is effective both orally or by intramuscular injection and has also been used to treat breast and endometrial neoplasms. ( CSP )] (UMLS (NCI) C0025147) =Steroid; Pharmacologic Substance; Hormone =[HS800] PROGESTINS;
17alpha-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione;
progesterone analog;
=(6alpha)-17-(Acetyloxy)-6-methylpregn-4-ene-3,20-dione | - 78. Alanine Aminotransferase Increased
- [An increase in the level of alanine aminotransferase in the blood. — 2003 ( NCI )] (UMLS (NCI) C0151905) =Finding
|
- 29. (6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
- [synthetic glucocorticoid derived from progesterone, used in replacement therapy for adrenal insufficiency and as an anti-inflammatory and immunosuppressant. ( CSP )] (UMLS (NCI) C0025815) =Steroid; Pharmacologic Substance; Hormone =[HS051] GLUCOCORTICOIDS;
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione =(7alpha,11beta,16alpha)-7-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione;
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 21-Acetate;
METHYLPREDNISOLONE SODIUM SUCCINATE;
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 21-Acetate;
METHYLPREDNISOLONE SODIUM SUCCINATE;
METHYLPREDNISOLONE 2 MG;
METHYLPREDNISOLONE 24 MG;
METHYLPREDNISOLONE 32 MG;
METHYLPREDNISOLONE 8 MG;
METHYLPREDNISOLONE 16 MG;
METHYLPREDNISOLONE 4 MG | - 79. Alanine and Aspartate Metabolism
- (UMLS (NCI) C1510839) Alanine and Aspartate Metabolism Pathway;
=Molecular Function |
- 30. (6alpha,11beta,16alpha)-21-(Acetyloxy)-6,9-difluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
- [A synthetic glucocorticoid and derivative of fluocinolone acetonide with anti-inflammatory and antipruritic activity. Fluocinonide binds the glucocorticoid receptor, followed by translocation of the ligand-receptor complex to the nucleus and transcription activation of genes containing glucocorticoid-responsive elements. Lipocortin-1 is one factor induced by fluocinonide that interacts and inhibits cytosolic phospholipase 2 alpha, thereby preventing phospholipase translocation to the perinuclear membrane and subsequent release and conversion of arachidonic acid to inflammatory prostaglandins. In addition, MAPK phosphatase 1 is induced, thereby preventing the triggering of the MAPK cascade resulting in pro-inflammatory effects via Jun N-terminal kinase and c-Jun. Finally, fluocinonide binds to and inhibits nuclear factor kappa-B directly, resulting in inhibition of cyclooxygenase 2 transcription and subsequent prostaglandin synthesis. ( NCI )] (UMLS (NCI) C0016299) =Steroid; Pharmacologic Substance ;
=(6alpha,11beta,16alpha)-6,9-Difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione;
[DE200] ANTI-INFLAMMATORY, TOPICAL =FLUOCINONIDE 0.05 % | - 80. alanine racemase
- [A pyridoxal-phosphate protein that reversibly catalyzes the conversion of L-alanine to D-alanine. EC 5.1.1.1. ( MSH )] (UMLS (CSP) C0001900) =Amino Acid, Peptide, or Protein; Enzyme
|
- 31. (6alpha,11beta,16alpha)-6,9-Difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
- [The acetonide salt form of fluocinolone, a synthetic fluorinated corticosteroid with antiinflammatory, antipruritic and vasoconstrictive properties. Fluocinolone is a glucocorticoid receptor agonist that binds to cytoplasmic glucocorticoid receptors and subsequently translocates to the nucleus where it initiates the transcription of glucocorticoid-responsive genes such as lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes, both are potent mediators of inflammation. Fluocinolone exerts its vasoconstrictive effect through inhibition of nitric oxide synthase, thereby blocking nitric oxide production and effectively diminishing the effect of nitric oxide on vascular smooth muscles leading to reduced blood flow. ( NCI )] (UMLS (NCI) C0016298) =Steroid; Pharmacologic Substance ;
=Pregnadienes;
Steroids, Fluorinated;
FLUOCINOLONE;
=(6alpha,11beta,16alpha)-21-(Acetyloxy)-6,9-difluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione;
FLUNISOLIDE;
FLUOCINOLONE ACETONIDE PWDR,TOP;
FLUOCINOLONE ACETONIDE 0.2 %;
FLUOCINOLONE ACETONIDE 0.01 %;
FLUOCINOLONE ACETONIDE 0.025 %;
FLUOCINOLONE ACETONIDE 0.1 % | - 81. Alanine, N-acetyl-N-methyl-, 6-ester with 11-chloro-6, 21-dihydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-4,24-dioxa-9, 22-diazatetracyclo[19.3.1.1(10,24).0(3,5)]hexacosa-10,12,14[26], 16,18-pentaene-8,23-dione
- [An ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata. Maytansine binds to tubulin at the rhizoxin binding site, thereby inhibiting microtubule assembly, inducing microtubule disassembly, and disrupting mitosis. Maytansine exhibits cytotoxicity against many tumor cell lines and may inhibit tumor growth in vivo. (NCI04) ( NCI )] (UMLS (NCI) C0024975) =Organic Chemical; Pharmacologic Substance ;
|
- 32. (6alpha,11beta,16alpha,17alpha)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic Acid, S-(Fluoromethyl) Ester
- [The propionate salt form of fluticasone, a synthetic trifluorinated glucocorticoid receptor agonist with antiallergic, antiinflammatory and antipruritic effects. Binding and activation of the glucocorticoid receptor results in the activation of lipocortin that in turn inhibits cytosolic phospholipase A2, which triggers cascade of reactions involved in synthesis of inflammatory mediators, such as prostaglandins and leukotrienes. Secondly, mitogen-activated protein kinase (MAPK) phosphatase 1 is induced, thereby leads to dephosphorylation and inactivation of Jun N-terminal kinase directly inhibiting c-Jun mediated transcription. Finally, transcriptional activity of nuclear factor (NF)-kappa-B is blocked, thereby inhibits the transcription of cyclooxygenase 2, which is essential for prostaglandin production. ( NCI )] (UMLS (NCI) C0117996) =Organic Chemical; Pharmacologic Substance =FLUTICASONE;
=FLUTICASONE PROPIONATE 50 MCG;
FLUTICASONE PROPIONATE 500 MCG;
FLUTICASONE PROPIONATE 50 MCG/ACTUAT;
FLUTICASONE PROPIONATE 0.05 %;
FLUTICASONE PROPIONATE 110 MCG/ACTUAT;
FLUTICASONE PROPIONATE 44 MCG/ACTUAT;
FLUTICASONE PROPIONATE 220 MCG/ACTUAT;
FLUTICASONE PROPIONATE 250 MCG;
FLUTICASONE PROPIONATE 100 MCG;
FLUTICASONE PROPIONATE 0.005 % | - 82. Alaryngeal Speech
- [Methods of enabling a patient without a larynx or with a non-functional larynx to produce voice or speech. The methods may be pneumatic or electronic. (MeSH) ( NCI )] (UMLS (NCI) C0037833) =Finding
|
- 33. (7alpha,11beta,16alpha)-7-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione
- [The dipropionate salt form of alclometasone, a synthetic corticosteroid with low to medium potency. Alclometasone dipropionate is a glucocorticoid receptor agonist that mimics the metabolic, anti-inflammatory, immunosuppressive, antipruritic, and vasoconstrictive effects of natural glucocorticoids. This drug interacts with specific intracellular receptors and binds to DNA to modify gene expression. This results in an induction of synthesis of certain proteins while inhibiting the synthesis of others. Alclometasone dipropionate is used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. (NCI05) ( NCI )] (UMLS (NCI) C0051113) =Steroid; Pharmacologic Substance ;
=(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione;
ALCLOMETASONE =ALCLOMETASONE DIPROPIONATE 0.05 %;
| - 83. Alaska Indian
- [Denotes a person having origins in any indigenous people of Alaska and their descendants and who maintains tribal affiliation, or community or cultural attachment. The concept refers to population subgroups such as Eskimos, Aleuts, Inupiat, Yupik, Alutiiq, Egegik,and Pribilovian, Alaskan Athabascan, Tlingit, and Haida. The concept refers also to individuals who classify themselves as described below. ( NCI )] (UMLS (NCI) C0682125) =Population Group =Alaska Indian;
American Indian or Alaska Native =Alaskan Athabascan;
Southeast Alaska;
Eskimo;
Aleut;
Alaska Indian |
- 34. (9alpha,10beta,11beta,13alpha)-(+)-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H-9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one
- [exhibits cytotoxic or antitumor properties; naturally derived from cultures of Streptomyces; inhibits protein kinase C. ( CSP )] (UMLS (NCI) C0075193) =Organic Chemical; Pharmacologic Substance ;
=alkaloid;
| - 84. Alaskan Malamute
- [The Alaskan Malamute is a large, strong dog with a thick, coarse double coat and a plumed tail held over the back. The feet are furry and have tough pads. The coat averages 1-3 inches in length and comes in white, black and white, wolf gray, wolf sable (red undercoat with dark gray outer coat), or red, often with darker highlights and sometimes with a dark mask or cap. Height: 22-26 inches (56-66 cm.) Weight: 70-95 pounds (32-43 kg.) ( NCI )] (UMLS (NCI) C0324301) =Mammal
|
- 35. (All-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic Acid
- [A naturally-occurring acid of retinol. Tretinoin binds to and activates retinoic acid receptors (RARs), thereby inducing changes in gene expression that lead to cell differentiation, decreased cell proliferation, and inhibition of tumorigenesis. This agent also inhibits telomerase, resulting in telomere shortening and eventual apoptosis of some tumor cell types. The oral form of tretinoin has teratogenic and embryotoxic properties. ( NCI )] (UMLS (NCI) C0040845) =Organic Chemical; Pharmacologic Substance =[AN000] ANTINEOPLASTICS;
[VT050] VITAMIN A;
[DE752] ANTIACNE AGENTS, TOPICAL;
=3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)2-trans-4-trans-6-cis-8-trans-nonatetraenoic Acid;
TRETINOIN 10 MG;
TRETINOIN PWDR;
TRETINOIN 0.05 %;
TRETINOIN 0.1 %;
TRETINOIN 0.01 %;
TRETINOIN 0.025 %;
TRETINOIN 0.04 %;
| - 85. Alaskan Native American
- [Native Americans whose ethnic origins are above the 48th parallel. ( CSP )] (UMLS (CSP) C0597091) =Population Group ;
=Native American;
|
- 36. (All-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic Acid
- [A drug used in cancer prevention that belongs to the family of drugs called retinoids. It is also used in the treatment of psoriasis. ( NCI )] (UMLS (NCI) C0050559) =Organic Chemical; Pharmacologic Substance ;
=Retinoic Acid Agent;
[DE801] ANTIPSORIATICS, SYSTEMIC =ACITRETIN 10 MG;
ACITRETIN 25 MG | - 86. ALASTRIM
- (UMLS (ICD9CM) C0001906) =Disease or Syndrome ;
|
- 37. (all-Z)-5,8,11,14-Eicosatetraenoic Acid
- [An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.(ChemID Plus) ( NCI )] (UMLS (NCI) C0003695) =Eicosanoid ;
| - 87. Alatna Village
- (UMLS (HL7) C1550800) =Population Group =NativeEntityAlaska;
|
- 38. .alpha.-Linolenic acid
- [An essential fatty acid belonging to the omega-3 fatty acids group. It is highly concentrated in certain plant oils and has been reported to inhibit the synthesis of prostaglandin resulting in reduced inflammation and prevention of certain chronic diseases. ( NCI )] (UMLS (NCI) C0051405) =Lipid; Biologically Active Substance ;
=Fatty Acids, Omega-3;
Linolenic Acids =LINOLENIC ACID | - 88. Alatrofloxacin Mesylate
- (UMLS (NCI) C0724517) ALATROFLOXACIN MESYLATE PREPARATION;
=Organic Chemical; Pharmacologic Substance ;
=ALATROFLOXACIN;
=ALATROFLOXACIN MESYLATE 5 MG/ML |
- 39. 1-((6-Allylergolin-8beta-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea
- [A synthetic ergoline derivative and a long-acting dopamine receptor agonist with high affinity for the dopamine D2 receptor. Cabergoline exerts an inhibitory effect on prolactin secretion by acting on dopamine receptors present in pituitary lactotrophes. This drug also binds to dopamine D2 receptors in the corpus striatum, thereby mimicking the actions of dopamine on motor control. Cabergoline also possesses antioxidant and neuroprotective properties due to its free radical scavenging activity. Cabergoline is used in the treatment of Parkinson's disease and in the treatment of hyperprolactinemia. ( NCI )] (UMLS (NCI) C0107994) =Organic Chemical; Pharmacologic Substance =ergoline;
[AU900] AUTONOMIC AGENTS, OTHER =CABERGOLINE 0.5 MG | - 89. Alazarin red S stain
- [Stain, Alazarin red S ( HL7V3.0 )] (UMLS (HL7) C1293951) =Laboratory Procedure =ObservationMethod;
|
- 40. 1-(alpha-methoxymethyl ethanol)-2-Nitroimidazole
- [1-(alpha-methoxymethyl ethanol)-2-nitroimidazole; trichimonicide and experimental mutagen and radiosensitizer, probably due to its ability to form DNA-attacking free radical under hypoxic conditions. ( CSP )] (UMLS (NCI) C0026218) =Organic Chemical; Pharmacologic Substance =Antiprotozoal Agent;
imidazole;
Radiation Sensitizers;
| - 90. ALB
- [A quantitative measurement of albumin present in a sample. ( NCI )] (UMLS (NCI) C0201838) =Laboratory Procedure
|
- 41. 1-Allyl-3,4-methylenedioxybenzene
- [A naturally-occurring, colorless to slightly yellow liquid that is soluble in ethanol, ether, and chloroform. Safrole is no longer used in the United States. Minimal exposure to safrole may occur through the use of edible spices, including nutmeg and mace, which contain low levels of this compound. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0036049) =Organic Chemical; Hazardous or Poisonous Substance
| - 91. ALBENDAZOLE
- [A broad-spectrum, synthetic benzimidazole-derivative anthelmintic. Albendazole interferes with the reproduction and survival of helminths by inhibiting the formation of microtubules from tubulin. This leads to an impaired uptake of glucose, a depletion of glycogen stores, and results in the worm's death. Albendazole is used in the treatment of dog and pork tapeworm-causing diseases, including hydatid disease and neurocysticercosis. Albendazole may also be used to treat a variety of other roundworm infections. (NCI05) ( NCI )] (UMLS (NCI) C0001911) =Organic Chemical; Pharmacologic Substance
|
- 42. 12-Allyldeoxoartemisinin
- [A semi-synthetic analogue of Artemisinin - a sesquiterpene lactone extracted from the dry leaves of Artemisia Annua (sweet wormwood) used as anti-malaria agent. Limited data is available on Artemisinin antineoplastic activity. ( NCI )] (UMLS (NCI) C0294412) =Organic Chemical; Pharmacologic Substance ;
| - 92. Albenza
- (UMLS (NCI) C0591462) =Organic Chemical; Pharmacologic Substance ;
|
- 43. 16alpha-Fluoroandrost-5-en-17-one
- (UMLS (NCI) C0539515) =Steroid; Pharmacologic Substance ;
| - 93. Albers Schoenberg disease
- [excessive formation of dense trabecular bone leading to pathological fractures, osteitis, splenomegaly with infarct, anemia, and extramedullary hemopoiesis. ( CSP )] (UMLS (CSP) C0029454) =Congenital Abnormality; Disease or Syndrome =bone development disorder;
osteosclerosis |
- 44. 17 Alpha-methyl-delta4-androsten-17beta-ol-4-one
- (UMLS (NCI) C1449554) =Steroid; Pharmacologic Substance
| - 94. Alberta (US and Canada)
- (UMLS (HL7) C1548668) =Geographic Area =State/province;
|
- 45. 17-(Allylamino)-17-demethoxygeldanamycin
- [A benzoquinone antineoplastic antibiotic derived from the antineoplastic antibiotic geldanamycin. Tanespimycin binds to and inhibits the cytosolic chaperone functions of heat shock protein 90 (HSP90). HSP90 maintains the stability and functional shape of many oncogenic signaling proteins; the inhibition of HSP90 promotes the proteasomal degradation of oncogenic signaling proteins that may be overexpressed by tumor cells. ( NCI )] (UMLS (NCI) C0675974) =Organic Chemical; Antibiotic ;
| - 95. albinism
- [general term for a number of inherited defects of amino acid metabolism in which there is a deficiency or absence of pigment in the eyes, skin, or hair. ( CSP )] (UMLS (CSP) C0001916) =Congenital Abnormality ;
|
- 46. 17alpha-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione
- [principal progestational hormone, secreted by the corpus luteum, placenta, and in minute amounts by the adrenal cortex; it prepares the uterus for the reception and development of the fertilized ovum; it acts on the mammary glands and on the brain; it serves as an intermediate in the biosynthesis of sex steroids and adrenal corticosteroids. ( CSP )] (UMLS (NCI) C0033308) =Steroid; Pharmacologic Substance; Hormone =C21 steroid;
Pregnenediones;
[HS800] PROGESTINS;
gonadal steroid hormone =HYDROXYPROGESTERONE;
(6Alpha)-17-hydroxy-6-methylpregn-4-ene-3,20-dione;
PROGESTERONE 2.5 MG;
PROGESTERONE 25 MG/ML;
PROGESTERONE 50 MG/ML;
PROGESTERONE 100 MG;
PROGESTERONE PWDR;
PROGESTERONE 200 MG;
PROGESTERONE 8 %;
PROGESTERONE 4 %;
| - 96. albino mouse
- [ ] (UMLS (CSP) C0684073) =Mammal ;
=laboratory mouse;
|
- 47. 1alphaH,5alphaH-Tropan-3alpha-ol, 6beta,7beta-epoxy-,(-)-tropate(ester)
- [anticholinergic alkaloid. ( CSP )] (UMLS (NCI) C0036442) =Organic Chemical; Pharmacologic Substance =alkaloid;
Belladonna Alkaloids;
1alphaH,5alphaH-Tropan-3alpha-ol, 6beta,7beta-epoxy-,(-)-tropate(ester);
tropane;
Anticholinergic Agent;
[CN550] ANTIVERTIGO AGENTS =1alphaH,5alphaH-Tropan-3alpha-ol, 6beta,7beta-epoxy-,(-)-tropate(ester);
Scopolamine Derivatives;
HYOSCINE HYDROBROMIDE;
SCOPOLAMINE 0.33 MG | - 97. albino rat
- [albino form of Rattus rattus or of R. norvegicus which is much used as a laboratory animal. ( CSP )] (UMLS (CSP) C0684072) =Mammal ;
=laboratory rat;
|
- 48. 1alphaH,5alphaH-Tropanium, 6beta,7beta-epoxy-3alpha-hydroxy-8-methyl-, bromide,(-)-tropate(8CI)
- [The bromide salt form of methscopolamine, a quaternary ammonium derivative of scopolamine with anticholinergic properties. Methscopolamine bromide exerts its effect on muscarine receptors in the gastrointestinal tract, thereby blocking the actions of acetylcholine. This leads to an inhibition of gastric secretions and gastrointestinal motility. ( NCI )] (UMLS (NCI) C0141756) =Organic Chemical; Pharmacologic Substance =METHSCOPOLAMINE;
=METHSCOPOLAMINE BROMIDE 2.5 MG | - 98. Albright's hereditary osteodystrophy
- [hereditary condition clinically resembling hypoparathyroidism, but caused by failure of response to rather than deficiency of parathyroid hormones; characterized by hypocalcemia and hyperphosphatemia, and commonly associated with short stature, obesity, short metacarpals, and ectopic calcification. ( CSP )] (UMLS (CSP) C0033806) =Disease or Syndrome =Bone Diseases, Metabolic;
calcium metabolism disorder;
Congenital Metabolic Disorder;
inborn metal metabolism disorder;
calcium disorder;
=Pseudopseudohypoparathyroidism |
- 49. 2 Alpha-Methyldihydrotestosterone Propionate
- [The propionate salt form of dromostanolone, a synthetic anabolic steroid related to dihydrotestosterone that has antiestrogenic effects. Dromostanolone inhibits the growth of estrogen receptor-presenting breast cancers; its virilizing effects limit its clinical usefulness. (NCI) ( NCI )] (UMLS (NCI) C0058758) =Steroid; Pharmacologic Substance
| - 99. Albright's Solution
- [The sodium salt form of citrate with alkalinizing property. Upon absorption, sodium citrate dissociate and causes increased plasma bicarbonate concentration, thereby buffer excess H+, raise blood pH and reverse the clinical manifestations of acidosis. Furthermore, increased free sodium load could foster intravascular blood volume, and facilitate excretion of bicarbonate compounds and result in anti-urolithic effect. ( NCI )] (UMLS (NCI) C0142825) =Organic Chemical; Pharmacologic Substance ;
=[TN410] CITRATES;
[TN404] SODIUM =Sodium Citrate Anhydrous;
ISOSOURCE LIQUID (CLOSED SYSTEM);
Acetaminophen 33.3 MG/ML / Diphenhydramine 1.67 More… |
- 50. 2alpha,3beta,23-Trihydroxyurs-12-en-28-oic Acid
- (UMLS (NCI) C0081660) =Organic Chemical; Pharmacologic Substance ;
| - 100. albumin
- [family of globular proteins found in many plant and animal tissues that tend to bind a wide variety of ligands. ( CSP )] (UMLS (CSP) C0001924) =Amino Acid, Peptide, or Protein; Biologically Active Substance
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