- 1. Friday
- (UMLS (NCI) C0585029) =Temporal Concept =Days of the week;
| - 11. Frizzled 4
- [Frizzled 4, encoded by the human FZD4 gene, is a G protein-coupled receptor that has seven transmembrane domains. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. It may function in cell polarity, cell fate specification and cancer. (From LocusLink, Swiss-Prot and NCI) ( NCI )] (UMLS (NCI) C1333639) FZD4;
=Amino Acid, Peptide, or Protein; Receptor |
- 2. Friedlander's bacillus infection in conditions classified elsewhere and of unspecified site
- (UMLS (ICD9CM) C0016717) =Disease or Syndrome ;
| - 12. Frizzled 6
- [Frizzled 6, encoded by the human FZD6 gene, is a G protein-coupled receptor for Wnt signaling proteins. The FZD6 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and 7 transmembrane domains. However, unlike many other Fz family members, FDZ6 does not contain a C-terminal PDZ domain-binding motif. Frizzled 6 may function in tissue polarity, development and carcinogenesis. (From LocusLink and NCI) ( NCI )] (UMLS (NCI) C1259397) FZD6;
FZD6 Protein;
=Amino Acid, Peptide, or Protein; Receptor ;
|
- 3. Friend
- (UMLS (HL7) C1546502) =Idea or Concept =Association;
| - 13. Frizzled 7
- [Frizzled 7, encoded by the human FZD7 gene, is a G protein-coupled receptor for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression downregulates APC function and enhances beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. (From LocusLink and NCI) ( NCI )] (UMLS (NCI) C1259399) Frizzled Homolog 7 (Drosophila);
Frizzled, Drosophila, Homolog of, 7;
Frizzled-7;
Fz-7;
FZD7;
FZD7 Protein;
FZE3;
hFz7;
=Amino Acid, Peptide, or Protein; Receptor ;
|
- 4. Friend leukemia
- [leukemia of the reticulum-cell type with massive infiltration of liver, spleen, and bone marrow, caused by the Friend murine leukemia virus. ( CSP )] (UMLS (CSP) C0678128) =Neoplastic Process =mouse leukemia;
viral leukemia | - 14. Frizzled 9
- [Frizzled 9, encoded by the human FZD9 gene, is a G protein-coupled receptor for Wnt signaling proteins. This gene has been first described as FZD3 in literature. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney. Frizzled 9 may function in tissue polarity, development and carcinogenesis. Heterozygous deletion of the FZD3 gene may contribute to the Williams syndrome phenotype. (From LocusLink and NCI) ( NCI )] (UMLS (NCI) C1333642) FZD9;
FZD9 Protein;
=Amino Acid, Peptide, or Protein; Receptor |
- 5. Friend Spleen Focus-Forming Virus
- [Defective virus found in certain strains of Friend virus, detected by its ability to form foci in spleens of mice and believed to be responsible in those strains for the production of a leukemia associated with polycythaemia rather than anemia. (DictionaryBarn.com) ( NCI )] (UMLS (NCI) C0037994) =Virus ;
| - 15. Frizzled Homolog 3 (Drosophila) Gene
- [This gene plays a regulatory role in signal transduction via the beta-catenin pathway in endothelial cells. ( NCI )] (UMLS (NCI) C1333585) FZD3;
FZD3 Gene =Gene or Genome ;
|
- 6. Friends
- (UMLS (HL7) C1697767) =Intellectual Product =Religious Affiliation;
| - 16. Frizzled Homolog 4 (Drosophila) Gene
- [This gene plays a role in signal transduction; however, its exact function is unknown. ( NCI )] (UMLS (NCI) C1333586) FZD4;
FZD4 Gene =Gene or Genome ;
|
- 7. friendship
- [attached to another by affection or esteem; a favored companion. ( CSP )] (UMLS (CSP) C0178647) =Social Behavior =interpersonal relations;
| - 17. Frizzled Homolog 6 (Drosophila) Gene
- [This gene plays a role in signal transduction and may play a role in tissue polarity or development. ( NCI )] (UMLS (NCI) C1333587) FZD6;
FZD6 Gene =Gene or Genome ;
|
- 8. Frizzled 2
- [Frizzled 2, encoded by the human FZD2 gene, is a 7-transmembrane domain protein that is a receptor with a role in transmembrane signal transmission for Wnt signaling proteins. The expression of the FZD2 gene appears to be developmentally regulated, with high levels of expression in fetal kidney and lung and in adult colon and ovary. (From LocusLink and NCI) ( NCI )] (UMLS (NCI) C1333637) Frizzled Homolog 2 (Drosophila);
Frizzled, Drosophila, Homolog of, 2;
Frizzled-2;
Fz-2;
FZD2;
FZD2 Protein;
FzE2;
hFz2 =Amino Acid, Peptide, or Protein; Receptor | - 18. Frizzled Homolog 7 (Drosophila) Gene
- [This gene is involved in the receptor-mediated Wnt signaling pathway. ( NCI )] (UMLS (NCI) C1333588) FZD7;
FZD7 Gene =Gene or Genome ;
|
- 9. Frizzled 2 Gene
- [This gene plays a regulatory role in signal transduction by calcium release from intracellular stores. ( NCI )] (UMLS (NCI) C1333584) FZD2;
FZD2 Gene =Gene or Genome ;
| - 19. Frizzled Homolog 9 (Drosophila) Gene
- [This gene is involved in the developmental regulation of the central nervous system. ( NCI )] (UMLS (NCI) C1333589) FZD9;
FZD9 Gene =Gene or Genome ;
|
- 10. Frizzled 3
- [Frizzled 3, encoded by the human FZD3 gene, is a G protein-coupled receptor for Wnt proteins and regulates signal transduction in endothelial cells via beta-catenin. It may function in both normal and pathological vasculature differentiation. It also may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Two isoforms are produced by alternative splicing. This protein is widely expressed with relatively high expression in the CNS, including regions of the limbic system, in kidney, pancreas, skeletal muscle, uterus and testis. (From LocusLink, Swiss-Prot and NCI) ( NCI )] (UMLS (NCI) C1175384) Frizzled 3 Protein;
Frizzled Homolog 3 (Drosophila);
Frizzled, Drosophila, Homolog of, 3;
Fz-3;
FZD3;
FZD3 Protein;
hFz3 =Amino Acid, Peptide, or Protein; Receptor | - 20. Frizzled-Related Protein
- [Encoded by human SFRP4 Gene (SFRP Family), Secreted Frizzled-Related Protein 4 is a soluble modulator of WNT signaling that contains an N-terminal signal peptide, no transmembrane domain, a hydrophilic C terminus, and a Cys-rich domain homologous to the putative WNT-binding site of Frizzled proteins. Involved in cytoskeletal regulation, apoptosis, and proliferation, WNT-mediated simulation of 'Frizzled' receptors can activate beta-catenin, MAPK kinase, and G protein pathways. Bound to WNTs or frizzled receptors, secreted frizzled-related proteins antagonize WNT/frizzled pathways. SFRP4 may inhibit WNT8-mediated development of secondary axes. (NCI) ( NCI )] (UMLS (NCI) C0913338) FRPHE;
Secreted Frizzled-Related Protein 4;
SFRP4;
=Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
home
