- 1. ARF GTPase-activating protein GIT2
- [This protein is a member of the GIT protein family. GIT proteins interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. The gene undergoes extensive alternative splicing. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding. ( NCI )] (UMLS (NCI) C1333737) Cool-Associated Tyrosine Phosphorylated Protein 2;
G Protein-Coupled Receptor Kinase-Interactor 2;
GIT2;
=Amino Acid, Peptide, or Protein; Biologically Active Substance | - 2. ARFORMOTEROL
- [A long-acting beta-2 adrenergic agonist and isomer of formoterol with bronchodilator activity. Arformoterol selectively binds to and activates beta-2 adrenergic receptors in bronchiolar smooth muscle, thereby causing stimulation of adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased intracellular cAMP levels cause relaxation of bronchial smooth muscle and lead to a reduced release of inflammatory mediators from mast cells. This may eventually lead to an improvement of airway function. ( NCI )] (UMLS (NCI) C0969589) =Organic Chemical; Pharmacologic Substance ;
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