[A platinum(IV) analogue with antineoplastic activity. Also known as tetraplatin, ormaplatin alkylates DNA, forming both inter- and intra-strand platinum-DNA crosslinks, which result in inhibition of DNA replication and transcription and cell-cycle nonspecific cytotoxicity. (NCI04) ( NCI )]
UMLS (NCI) C0076329 - Organic Chemical
- Pharmacologic Substance