- 1. 1,1'-Oxybisethane
- [An organic compound in which two carbon atoms are linked through an oxygen atom (C-O-C). An ether may be a product of the condensation of alcohols. Ether also refers loosely to diethyl-ether, a colorless, volatile, highly inflammable liquid used in industry and biomedical research, and historically important as an anesthetic agent. In vivo, ether acts similarly to alcohol and chloroform, but its stimulant action on the heart is much more marked. Ether is a rapidly diffusible stimulant. (NCI04) ( NCI )] (UMLS (NCI) C0014994) =Organic Chemical; Pharmacologic Substance ;
=1,1'-Oxybisethane;
Ethyl Ethers;
Organic Chemical;
[CN201] ANESTHETICS INHALATION =Ethers, Cyclic;
Ethyl Ethers;
Methyl Ethers;
Phenyl Ethers;
1,1'-Oxybisethane;
ETHER 57 %;
ETHER 65 %;
ETHER 69 % | - 46. oxime
- [compounds containing the group C=NOH. ( CSP )] (UMLS (CSP) C0030020) =Organic Chemical ;
=Hydroxylamines;
nitrogen oxide =Fluoxamine;
Pralidoxime Compounds;
technetium Tc 99m teboroxime;
Fluoxamine |
- 2. 1,2-Oxathiolane 2,2-Dioxide
- [A synthetic, colorless liquid or white crystalline solid that is readily soluble in water and many organic solvents such as ketones, esters and aromatic hydrocarbons. 1,3-propanesultone is used as a chemical intermediate in the production of detergents, dyes, lathering agents, bacteriostats, fungicides, insecticides, cation-exchange resins, corrosion inhibitors and vulcanization accelerators. When heated to decomposition, it emits toxic fumes of sulfur oxides. Humans are potentially exposed to residues of 1,3-propane sultone when using products manufactured from this compound. The primary routes of potential human exposure to 1,3-propane sultone are ingestion and inhalation. Contact with this chemical can cause mild irritation of the eyes and skin. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0043970) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance
| - 47. OXINDANAC
- (UMLS (NCI) C0069768) =Organic Chemical; Pharmacologic Substance ;
|
- 3. 1-(2-Oxo-4-amino-1,2-dihydropyrimidin-1-yl)-2-deoxy-2,2-difluororibose
- [antimetabolite used in the treatment of pancreatic, lung, and other cancers. ( CSP )] (UMLS (NCI) C0045093) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=antimetabolite;
[AN000] ANTINEOPLASTICS;
deoxycytidine;
=1-(2-Oxo-4-amino-1,2-dihydropyrimidin-1-yl)-2-deoxy-2,2-difluororibose, hydrochloride | - 48. oxindole
- [ ] (UMLS (CSP) C0598684) =Amino Acid, Peptide, or Protein; Biologically Active Substance
|
- 4. 1-(2-Oxo-4-amino-1,2-dihydropyrimidin-1-yl)-2-deoxy-2,2-difluororibose, hydrochloride
- [The hydrochloride salt of an antimetabolite analog of the nucleoside pyrimidine with antineoplastic activity. Gemcitabine is converted intracellularly to the active metabolites difluorodeoxycytidine di- and triphosphate (dFdCDP, dFdCTP). dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis. ( NCI )] (UMLS (NCI) C0771488) 2'Deoxy-2',2'-Difluorocytidine, Hydrochloride;
Difluorodeoxycytidine Hydrochloride;
Gemcitabine Hydrochloride;
GEMCITABINE HYDROCHLORIDE PREPARATION =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=1-(2-Oxo-4-amino-1,2-dihydropyrimidin-1-yl)-2-deoxy-2,2-difluororibose;
=GEMCITABINE HYDROCHLORIDE 1 GM;
GEMCITABINE HYDROCHLORIDE 200 MG | - 49. OXINIACIC ACID
- (UMLS (NCI) C0873176) =Organic Chemical; Pharmacologic Substance
|
- 5. 2,4-Oxazolidinedione, 3,5,5-trimethyl-
- [A dione-type anticonvulsant with antiepileptic activity. Trimethadione reduces T-type calcium currents in thalamic neurons, thereby stabilizing neuronal membranes, raising the threshold for repetitive activities in the thalamus and inhibiting corticothalamic transmission. This decreases the abnormal thalamocortical rhythmicity, which is thought to underlie the paroxysmal three-cycle-per-second spike-and-wave pattern seen with absence (petit mal) seizures. ( NCI )] (UMLS (NCI) C0041038) =Organic Chemical; Pharmacologic Substance ;
=[CN400] ANTICONVULSANTS;
oxazole =TRIMETHADIONE 150 MG;
TRIMETHADIONE 300 MG;
TRIMETHADIONE 40 MG/ML | - 50. OXIPEROMIDE
- (UMLS (NCI) C0069771) =Organic Chemical; Pharmacologic Substance ;
|
- 6. 2-Oxazolidinone, 4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)methyl)-,(S)-
- [A member of the triptan class agents with anti-migraine property. Zolmitriptan selectively binds to and activates serotonin (5-HT) 1B expressed in intracranial arteries and 5_HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and central terminals in brain stem sensory nuclei. Receptor binding results in constriction of cranial vessels, reduction of the vessel pulsation and inhibition of nociceptive transmission, thereby providing relief of migraine headaches. Zolmitriptan may also relief migraine headaches by inhibition pro-inflammatory neuropeptide release. ( NCI )] (UMLS (NCI) C0528166) =Organic Chemical; Pharmacologic Substance ;
=[CN105] ANTIMIGRAINE AGENTS;
Oxazolidinones =ZOLMITRIPTAN 2.5 MG;
ZOLMITRIPTAN 5 MG;
| - 51. Oxiracetam
- (UMLS (NCI) C0069772) =Organic Chemical; Pharmacologic Substance ;
|
- 7. 2-Oxazolidinone, 5-((3,5-dimethylphenoxy)methyl)-
- [An oxazolidinone with centrally-acting skeletal muscle relaxant properties. Although the exact mechanism through which metaxalone exerts its effect is largely unknown, it might be due to general central nervous system (CNS) depression. Metaxalone has no direct effect on the contractile mechanisms of striated muscle, the motor end plate, or the nerve fiber. ( NCI )] (UMLS (NCI) C0163055) =Organic Chemical; Pharmacologic Substance ;
=[MS200] SKELETAL MUSCLE RELAXANTS;
Oxazolidinones =METAXALONE 400 MG;
METAXALONE 800 MG;
| - 52. OXO
- [The potassium salt of oxonate, an enzyme inhibitor that modulates 5- fluorouracil (5-FU) toxicity. Oxonate (Oxo), one of the components of the antineoplastic agent S1, inhibits the enzyme orotate phosphoribosyltransferase which catalyzes the conversion of 5-FU to its active or phosphorylated form, FUMP. Upon oral administration, Oxo is selectively distributed to the intracellular sites of tissues lining the small intestines, thereby, producing localized inhibitory effects within the gastrointestinal tract. As a result, 5-FU associated gastrointestinal toxic effects are reduced and the incidence of diarrhea or mucositis is decreased with S1 therapy. ( NCI )] (UMLS (NCI) C0393003) =Organic Chemical; Pharmacologic Substance ;
|
- 8. 2-Oxetanone
- [A colorless, highly reactive, liquid, cyclic ether with a slightly sweet odor. Beta-propiolactone was used once mainly in the manufacture of acrylic acid and esters. It also was used as a sterilant for medical materials and procedures. However, it is no longer used for medical disinfection. Dermal exposure to beta-propiolactone causes the burning or blistering of the skin, and ingestion of this substance burns the mouth and stomach while exposure to its vapors causes severe irritation of the eyes, throat and respiratory tract. This substance is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0033472) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance
| - 53. oxoacid lyase
- [ ] (UMLS (CSP) C0597154) =Amino Acid, Peptide, or Protein; Enzyme =carbon carbon lyase;
=citrate (si) synthase;
|
- 9. 2-oxo-N,3-bis-(2-chloroethyl) tetrahydro-2H-1,3,2-oxazaphosphorin- 2-amine
- [2-oxo-N,3-bis-(2-chloroethyl) tetrahydro-2H-1,3,2-oxazaphosphorin- 2-amine; cyclophosphamide analog with two alkylating groups, used as a DNA strand crosslinker and antineoplastic. ( CSP )] (UMLS (NCI) C0020823) =Organophosphorus Compound; Pharmacologic Substance ;
=Alkylating Activity;
[AN000] ANTINEOPLASTICS;
(-)-Cyclophosphamide;
phosphamide;
oxazine;
Antineoplastic Alkylating Agent =IFOSFAMIDE 1 GM/VIL;
IFOSFAMIDE 3 GM;
IFOSFAMIDE 1 GM;
| - 54. oxoglutarate decarboxylase
- [ ] (UMLS (CSP) C0311624) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 10. 22-Oxovincaleukoblastine
- [inhibits microtubule formation in the mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. ( CSP )] (UMLS (NCI) C0042679) =Organic Chemical; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
vinca alkaloid =Leurocristine Sulfate | - 55. Oxolamine
- (UMLS (NCI) C0069787) =Organic Chemical; Pharmacologic Substance ;
|
- 11. 3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 2
- [catalyzes the reduction of testosterone to 5 alphadihydrotestosterone. ( CSP )] (UMLS (NCI) C0039602) =Amino Acid, Peptide, or Protein; Enzyme ;
=hydrocarbon oxidoreductase;
| - 56. oxotremorine
- [A non-hydrolyzed muscarinic agonist used as a research tool. ( MSH )] (UMLS (CSP) C0030038) =Organic Chemical; Pharmacologic Substance
|
- 12. 3-oxobutyrate
- [ ] (UMLS (CSP) C1536988) =Organic Chemical
| - 57. OXPRENOLOL
- [A lipophilic, nonselective beta-adrenergic receptor antagonist with anti-arrhythmic, anti-anginal and antihypertensive activities. Oxprenolol competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, oxprenolol prevents the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels. ( NCI )] (UMLS (NCI) C0030040) =Organic Chemical; Pharmacologic Substance
|
- 13. 4-Oxa-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, Monopotassium Salt,(2R-(2alpha,3Z,5alpha))-
- [A semi-synthetic beta-lactamase inhibitor isolated from streptomyces. Clavunalate potassium contains a beta-lactam ring and binds strongly to beta-lactamase at or near its active site. This protects other beta-lactam antibiotics from beta-lactamase catalysis. This drug is used in conjunction with beta-lactamase susceptible penicillins to treat infections caused by beta-lactamase producing organisms. ( NCI )] (UMLS (NCI) C0137997) =Organic Chemical; Antibiotic =CLAVULANATE;
=CLAVULANATE POTASSIUM 100 MG/100ML;
CLAVULANATE POTASSIUM 62.5 MG/5ML;
CLAVULANATE POTASSIUM 62.5 MG;
CLAVULANATE POTASSIUM 57 MG/5ML;
CLAVULANATE POTASSIUM 28.5 MG;
CLAVULANATE POTASSIUM 28.5 MG/5ML;
CLAVULANATE POTASSIUM 31.25 MG/5ML;
CLAVULANATE POTASSIUM 125 MG;
CLAVULANATE POTASSIUM 57 MG;
CLAVULANATE POTASSIUM 0.1 GM/VIL;
CLAVULANATE POTASSIUM 42.9 MG/5ML;
CLAVULANATE POTASSIUM 31.25 MG;
| - 58. OXPRENOLOL HYDROCHLORIDE
- [The hydrochloride salt form of oxprenolol, a lipophilic, nonselective beta-adrenergic receptor antagonist with anti-arrhythmic, anti-anginal and antihypertensive activities. Oxprenolol competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, oxprenolol prevents the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels. ( NCI )] (UMLS (NCI) C0700460) =Organic Chemical; Pharmacologic Substance
|
- 14. 8-Oxo-2'-Deoxyguanosine
- [A type of altered DNA base caused by oxidative DNA damage. ( NCI )] (UMLS (NCI) C0081381) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance
| - 59. OXT
- [peptide hormone produced by the posterior lobe of the pituitary gland that induces contraction of the smooth muscle of the uterus and the myoepithelial cells of the mammary gland. ( CSP )] (UMLS (NCI) C0030095) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Hormone =[GU600] OXYTOCICS;
[HS702] POSTERIOR PITUITARY;
reproductive hormone;
ADH =OXYTOCIN 10 UNT/ML |
- 15. 8-Oxoguanine DNA Glycosylase
- [The protein 8-Oxoguanine DNA Glycosylase, encoded by the OGG1 gene, is an enzyme in base excision repair. OGG1 incises DNA at 8-oxoguanine residues and excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-n-methylformamidopyrimidine (FAPY) from damaged DNA. OGG1 also has activities of beta-lyase that nicks DNA 3-prime to the lesion and endonuclease that cleaves DNA near apurinic or apyrimidinic sites to products with 5-prime-phosphate. Alternative splicing of the C-terminal region of the OGG1 gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common (1a/alpha, 1b, 1c, 2a/beta, 2b, 2c, 2d and 2e) and 1a is the prevalent form. OGG1 is ubiquitous and located in nucleus (isoform 1a) and mitochondria (isoform 2a). Defects in OGG1 are associated with tumor formation. ( NCI )] (UMLS (NCI) C1363852) N-Glycosylase/DNA Lyase;
OGG1 =Amino Acid, Peptide, or Protein; Enzyme | - 60. OXT
- [This gene plays a regulatory role in smooth muscle contraction during processes such as parturition and lactation. ( NCI )] (UMLS (NCI) C1418208) OXT Gene;
Oxytocin, Prepro- (Neurophysin I) Gene =Gene or Genome |
- 16. 8-Oxoguanine DNA Glycosylase Gene
- [This gene is involved in base excision repair of oxidatively damaged DNA. ( NCI )] (UMLS (NCI) C1335081) OGG1;
OGG1 Gene;
=Gene or Genome ;
| - 61. OXYCLOZANIDE
- [Anthelmintic used in grazing animals for fasciola and cestode infestations. ( MSH )] (UMLS (NCI) C0030046) =Organic Chemical; Pharmacologic Substance
|
- 17. OXACILLIN
- [A semisynthetic penicillinase-resistant and acid-stable penicillin with an antimicrobial activity. Oxacillin binds to penicillin-binding proteins in the bacterial cell wall, thereby blocking the synthesis of peptidoglycan, a critical component of the bacterial cell wall. This leads to inhibition of cell growth and causes cell lysis. ( NCI )] (UMLS (NCI) C0029983) =Organic Chemical; Antibiotic ;
=Penicillanic Acid;
[AM053] PENICILLINASE-RESISTANT PENICILLINS =CLOXACILLIN;
OXACILLIN SODIUM | - 62. Oxycodone Terephthalate
- [The terephthalate salt of oxycodone, a methylether of oxymorphone and semisynthetic, agonistic opioid with analgesic and antitussic properties. Oxycodone terephthalate exerts its analgesic actions by binding to the mu-receptors in the central nervous system (CNS), thereby mimicking the effects of endogenous opiates. By binding to the mu-opioid receptors, oxycodone terephthalate also causes euphoria, anxiolysis, miosis, sedation, physical dependence, constipation, respiratory depression as well as a depressive effect on the cough center in the medulla. ( NCI )] (UMLS (NCI) C0606954) =Organic Chemical; Pharmacologic Substance =4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one;
=OXYCODONE TEREPHTHALATE 0.19 MG;
OXYCODONE TEREPHTHALATE 0.38 MG;
|
- 18. oxalate
- [strong dicarboxylic acid or its salts or esters occurring in many plants; produced in the body by metabolism of glyoxylic acid or ascorbic acid; not metabolized but excreted in the urine. ( CSP )] (UMLS (CSP) C0029988) =Organic Chemical =dicarboxylate;
| - 63. OxyContin
- [A controlled-release form of oxycodone. ( MSH )] (UMLS (NCI) C0722364) =Organic Chemical; Pharmacologic Substance ;
|
- 19. Oxaliplatin/Paclitaxel
- (UMLS (NCI) C0879353) =Therapeutic or Preventive Procedure ;
| - 64. Oxygen
- (UMLS (HL7) C1547125) =Spatial Concept =Location Equipment;
|
- 20. Oxaliplatin/Topotecan
- (UMLS (NCI) C0935701) =Therapeutic or Preventive Procedure
| - 65. oxygen administration
- [inhalation of oxygen aimed at normalizing any pathophysiologic alterations of gas exchange in the cardiopulmonary system. ( CSP )] (UMLS (CSP) C0184633) =Therapeutic or Preventive Procedure ;
=respiratory therapy;
=hyperbaric oxygen therapy;
|
- 21. oxaloacetate
- [class of ketodicarboxylic acids, or their salts or esters, derived from oxalic acid; oxaloacetate is an intermediate in the citric acid cycle and is converted to aspartate by a transamination reaction. ( CSP )] (UMLS (CSP) C0029989) =Organic Chemical =dicarboxylate;
| - 66. oxygen compound
- [tree heading term for oxygen-containing chemicals. ( CSP )] (UMLS (CSP) C0684299) =Inorganic Chemical =Chemical;
=oxide;
O;
ozone;
free radical oxygen;
oxygenous heterocyclic compound |
- 22. oxalosis
- [ ] (UMLS (CSP) C1298681) =Disease or Syndrome
| - 67. oxygen consumption
- [rate at which oxygen is used by a tissue. ( CSP )] (UMLS (CSP) C0030055) =Clinical Attribute =respiratory oxygen;
|
- 23. OXAMNIQUINE
- [An anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp. Oxamniquine causes worms to shift from the mesenteric veins to the liver where the male worms are retained; the female worms return to the mesentery, but can no longer release eggs. (From Martidale, The Extra Pharmacopoeia, 31st ed, p121) ( MSH )] (UMLS (NCI) C0029994) =Organic Chemical; Pharmacologic Substance ;
=Anthelminthics;
Hydroxyquinolines;
Nitroquinolines;
| - 68. oxygen debt
- [ ] (UMLS (CSP) C0599064) =Organ or Tissue Function
|
- 24. Oxandrin
- (UMLS (NCI) C0728775) =Organic Chemical; Pharmacologic Substance; Hormone
| - 69. Oxygen Equipment & Supplies
- (UMLS (HL7) C1552497) =Intellectual Product ;
=Durable Medical Equipment & Medical Supplies;
|
- 25. OXANDROLONE
- [synthetic hormone with androgenic and anabolic properties. ( CSP )] (UMLS (NCI) C0029995) =Steroid; Pharmacologic Substance; Hormone =androgen analog;
Androstanols;
[HS100] ANDROGENS/ANABOLICS;
=OXANDROLONE 2.5 MG;
OXANDROLONE 10 MG | - 70. oxygen microelectrode
- [ ] (UMLS (CSP) C0597155) =Medical Device ;
=microelectrode;
|
- 26. oxazine
- [Six-membered heterocycles containing an oxygen and a nitrogen. ( MSH )] (UMLS (CSP) C0030001) =Organic Chemical ;
=Heterocyclic Compounds, 1-Ring;
nitrogenous heterocyclic compound;
oxygenous heterocyclic compound;
=flavin;
morpholine;
Efavirenz;
2-oxo-N,3-bis-(2-chloroethyl) tetrahydro-2H-1,3,2-oxazaphosphorin- 2-amine;
morpholine;
L 743726 | - 71. oxygen oxidase
- [ ] (UMLS (CSP) C0134407) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 27. oxaziridine
- [ ] (UMLS (CSP) C0597947) =Organic Chemical; Pharmacologic Substance
| - 72. oxygen poisoning
- [ ] (UMLS (CSP) C0238327) =Disease or Syndrome
|
- 28. oxazole
- [five-membered heterocyclic ring structures containing an oxygen in the 1-position and a nitrogen in the 3-position. ( CSP )] (UMLS (CSP) C0030004) =Organic Chemical ;
=azole;
Heterocyclic Compounds, 1-Ring =isoxazole;
oxazolidone;
isoxazole;
2-Imino-4-keto-5-phenyltetrahydrooxazole;
2,4-Oxazolidinedione, 3,5,5-trimethyl-;
PARAMETHADIONE;
Oxazolidinones;
| - 73. Oxygen Radical
- [An oxygen species that carries an unpaired electron (e.g., the hydroxyl radical and the superoxide anion). These radicals are very powerful oxidizing agents and cause structural damage to proteins and nucleic acids. They mediate the damaging effects of ionizing radiation. (from Online Medical Dictionary) ( NCI )] (UMLS (NCI) C0162772) =Biologically Active Substance; Element, Ion, or Isotope
|
- 29. oxazolidinedione
- [ ] (UMLS (CSP) C0304361) =Organic Chemical; Pharmacologic Substance
| - 74. oxygen tension
- [concentration of dissolved oxygen at which its partial pressure is in equilibrium with the solvent. ( CSP )] (UMLS (CSP) C1536627) =Physiologic Function; ;
=respiratory oxygen;
=Bohr effect;
|
- 30. oxazolidone
- [derivatives of oxazole; a class of synthetic antibiotic agents. ( CSP )] (UMLS (CSP) C0597149) =Organic Chemical ;
=oxazole;
| - 75. Oxygen therapy
- (UMLS (HL7) C1546419) =Finding =Ambulatory Status;
|
- 31. oxazolinone
- [ ] (UMLS (CSP) C0597150) =Organic Chemical ;
| - 76. oxygen transport
- [transfer of oxygen from lungs or other organs of respiration and delivery to tissue including exchange of oxygen between alveolar air and pulmonary capillary blood across the blood-air barrier, and binding or disassociation with hemoglobin. ( CSP )] (UMLS (CSP) C0597157) =Organ or Tissue Function ;
=blood gas transport;
respiratory oxygen =blood oxygen level dependent;
|
- 32. oxepane
- [ ] (UMLS (CSP) C0597151) =Organic Chemical ;
| - 77. Oxygenase
- [Enzymes acting on single donors with incorporation of molecular oxygen. EC 1.13.- ( NCI )] (UMLS (NCI) C0030065) =Amino Acid, Peptide, or Protein; Enzyme ;
=dehydrogenase;
=aryl 4 monooxygenase;
DBH (dopamine beta hydroxylase);
heme oxygenase;
carotene oxidase;
phenylalaninase;
COX;
CYP11B1;
CYP17A1;
tryptophan 5 hydroxylase;
tryptamine 2,3 dioxygenase;
cresolase;
tyrosine 3 monooxygenase;
methane monooxygenase;
EC 1.14.13.39;
luciferin monooxygenase;
7alpha hydroxylase |
- 33. oxepin
- [Compounds based on a 7-membered heterocyclic ring including an oxygen. They can be considered a medium ring ether. A natural source is the MONTANOA plant genus. Some dibenzo-dioxepins, called depsidones, are found in GARCINIA plants. ( MSH )] (UMLS (CSP) C0030007) =Organic Chemical ;
| - 78. oxygenous heterocyclic compound
- [ring compounds having oxygen atoms in their nuclei. ( CSP )] (UMLS (CSP) C0597158) =Organic Chemical ;
=Heterocyclic Compound;
oxygen compound =benzopyran;
epoxide;
LACTONE;
oxazine;
pyran;
2,3,7,8-Tetrachlorodibenzo[b,e][1,4]dioxin;
1,2-(methylenedioxy)benzene;
1,4-Epoxy-1,3-butadiene |
- 34. OXEPINAC
- (UMLS (NCI) C0069754) =Organic Chemical; Pharmacologic Substance
| - 79. oxyhemoglobin
- [compound formed by the combination of hemoglobin and O2 on exposure to alveolar gas; a complex in which the oxygen is bound directly to the iron without causing a change from the ferrous to the ferric state. ( CSP )] (UMLS (CSP) C0030069) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
=hemoglobin;
|
- 35. oxetane
- [cyclic ester, trimethylene oxide. ( CSP )] (UMLS (CSP) C0069755) =Organic Chemical ;
=epoxide;
| - 80. OXYMETAZOLINE
- [An imidazole derivative with direct acting sympathomimetic activity. Oxymetazoline binds to and activates alpha2-adrenergic receptors. Upon nasal or ocular administration, oxymetazoline constricts the arterioles in the nose and eye, resulting in decreased nasal and conjunctival congestion, respectively. ( NCI )] (UMLS (NCI) C0030071) =Organic Chemical; Pharmacologic Substance ;
=imidazole;
[OP800] DECONGESTANTS, TOPICAL OPHTHALMIC =Oxymetazoline Hydrochloride;
OXYMETAZOLINE 0.025 % |
- 36. OXi-104
- [An anticancer drug being evaluated in combination with cisplatin. ( NCI )] (UMLS (NCI) C0796491) =Organic Chemical; Pharmacologic Substance
| - 81. Oxymetazoline Hydrochloride
- [The hydrochloride salt form of oxymetazoline, an imidazole derivative with a direct acting sympathomimetic property. Oxymetazoline binds to and activates alpha2-adrenergic receptors. Upon nasal or ocular administration, oxymetazoline constricts the arterioles in the nose and eye, resulting in decreased nasal and conjunctival congestion, respectively. ( NCI )] (UMLS (NCI) C0357797) =Organic Chemical; Pharmacologic Substance =OXYMETAZOLINE;
[NT100] DECONGESTANTS, NASAL =OXYMETAZOLINE HYDROCHLORIDE 0.05 %;
OXYMETAZOLINE HYDROCHLORIDE 0.025 %;
|
- 37. OXIBENDAZOLE
- (UMLS (NCI) C0069763) =Organic Chemical; Pharmacologic Substance ;
| - 82. OXYMORPHONE
- [A semisynthetic narcotic analgesic related to hydromorphone and other opiates, Oxymorphone, hydroxy-dihydromorphinone, affects the central nervous system and smooth muscles by activation of specific opiate receptors. Similar to morphine, but more potent and without cough suppressant activity, it is used in treatment of moderate to severe pain, including obstetrical pain, or as an adjunct to anaesthesia. (NCI04) ( NCI )] (UMLS (NCI) C0030073) =Organic Chemical; Pharmacologic Substance ;
=[CN101] OPIOID ANALGESICS;
(-)-Hydromorphone =4,5-alpha-Epoxy-3,14-dihydroxy-17-methylmorphinan-6-one Hydrochloride;
|
- 38. OXICONAZOLE
- (UMLS (NCI) C0069765) =Organic Chemical; Pharmacologic Substance ;
=imidazole;
[DE102] ANTIFUNGAL, TOPICAL =OXICONAZOLE 1 % | - 83. OXYPHENBUTAZONE
- [A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27) ( MSH )] (UMLS (NCI) C0030078) =Organic Chemical; Pharmacologic Substance ;
=PHENYLBUTAZONE;
[MS102] NONSALICYLATE NSAIS, ANTIRHEUMATIC;
TO BE DELETED INGREDIENT PREPARATIONS;
|
- 39. oxidation
- [Process in which molecules are split to give products that have unpaired electrons. ( NCI )] (UMLS (NCI) C0030011) =Molecular Function ;
=oxidation reduction reaction;
=peroxidation;
oxidative stress;
autooxidation;
| - 84. OXYPHENCYCLIMINE
- (UMLS (NCI) C0069833) =Organic Chemical; Pharmacologic Substance ;
=parasympatholytic agent;
Pyrimidine;
TO BE DELETED INGREDIENT PREPARATIONS;
=Oxyphencyclimine Hydrochloride |
- 40. oxidation reduction reaction
- [chemical reaction in which electrons are transferred from one reactant to another. ( CSP )] (UMLS (CSP) C0030012) =Molecular Function ;
=chemical reaction;
=electron transfer;
oxidation;
reduction;
| - 85. Oxyphencyclimine Hydrochloride
- (UMLS (NCI) C0304424) =Organic Chemical; Pharmacologic Substance =OXYPHENCYCLIMINE;
=OXYPHENCYCLIMINE HYDROCHLORIDE 10 MG |
- 41. oxidative stress
- [damage to biological tissues caused by superoxide and other free radicals generated as a result of intoxication, antimicrobial cellular immunity, metabolic abnormality, or "normal" aging; do not confuse with HYPOXIA or HYPEROXIA. ( CSP )] (UMLS (NCI) C0242606) =Cell or Molecular Dysfunction ;
=oxidation;
injury | - 86. oxypurine
- [purine containing oxygen. ( CSP )] (UMLS (CSP) C0597159) =Organic Chemical ;
=purine;
=hypoxanthine;
xanthine;
urate;
|
- 42. oxide
- [any compound of oxygen with an element or radical. ( CSP )] (UMLS (CSP) C0030015) =Inorganic Chemical ;
=anion;
Oxygen Compounds;
oxygen compound;
=nitrogen oxide;
sulfur oxide;
WATER;
hydroxide;
metal oxide;
aluminum oxide;
carbon dioxide;
carbon monoxide;
Hypochlorous Acid;
MAGNESIA;
nitrogen oxide;
peroxide;
SILICA;
WATER;
C.I. Pigment White 4;
Arsenic (III) Oxide;
LEAD MONOXIDE;
Calcium oxide;
manganese dioxide;
mercuric oxide;
ferumoxides;
Ferumoxsil | - 87. oxypyrimidine
- [ ] (UMLS (CSP) C0597160) =Organic Chemical ;
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- 43. oxidized lipid
- [ ] (UMLS (CSP) C0597152) =Lipid ;
=lipid;
=lipid peroxide;
| - 88. oxysteroid
- [ ] (UMLS (CSP) C0597161) =Steroid ;
=Steroid;
=hydroxysteroid;
sterol ester |
- 44. Oxidoreductase Gene
- [Oxidoreductase Genes encode the class of enzymes that catalyze oxidation/reduction reactions (Oxidoreductases). The oxidized substrate is regarded as a hydrogen donor. Systematic enzyme names employ dehydrogenase wherever possible, or reductase; oxidase is only used where O2 is the acceptor. ( NCI )] (UMLS (NCI) C1335186) =Gene or Genome
| - 89. OXYTETRACYCLINE
- [A TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES rimosus and used in a wide variety of clinical conditions. ( MSH )] (UMLS (NCI) C0030092) =Organic Chemical; Antibiotic ;
=[AM250] TETRACYCLINES;
=(4S,4aR,5S,5aR,6S,12aS)-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide, Monohydrochloride;
OXYTETRACYCLINE CALCIUM;
(4S,4aR,5S,5aR,6S,12aS)-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide, Monohydrochloride;
OXYTETRACYCLINE CALCIUM;
OXYTETRACYCLINE 125 MG/ML;
OXYTETRACYCLINE 50 MG/ML |
- 45. oxidoreductase inhibitor
- [any substance or agent which suppresses, prevents or opposes the activity of enzymes which catalyze oxidation-reduction reactions. ( CSP )] (UMLS (CSP) C0597153) =Pharmacologic Substance ;
=enzyme inhibitor;
=MAO inhibitor;
6-Methoxy-alpha-methyl-2-naphthaleneacetic Acid;
cyclooxygenase inhibitor;
Xanthine Oxidase Inhibitor;
dopamine hydroxylase inhibitor;
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