[The sulfate salt form of paromomycin, a structural derivative of neomycin, an aminoglycoside antibiotic with amebicidal and bactericidal effects against predominantly aerobic gram-negative bacteria. Paromomycin binds specifically to the RNA oligonucleotide at the A site of bacterial 30S ribosomes, thereby causing misreading and premature termination of translation of mRNA and inhibition of protein synthesis followed by cell death. ( NCI )]
UMLS (NCI) C0205881 Relation/PAR: PAROMOMYCIN
Relation/CHD: PAROMOMYCIN SULFATE 250 MG