A A A+ A- A0 A1 A2 A3 A4 A5 A6 A7 A8 A9 AA AB AC AD AE AF AG AH AI AJ AK AL AM AN AO AP AQ AR AS AT AU AV AW AX AY AZ
AF5Q31
[ALL1 Fused Gene From 5q31, a protein encoded by the AF5q31 gene, is a transcription factor. It is expressed in fetal heart, lung, and brain at relatively high levels and in fetal liver at a low level, but the expression in these tissues is decreased in adults. The AF5q31 protein is homologous to AF4-related proteins, including AF4, LAF4, and FMR2. The AF5q31 and AF4 proteins have 3 homologous regions, including the transactivation domain of AF4. Infantile acute lymphoblastic leukemia (ALL) with rearrangements of the MLL gene is characterized by early pre-B phenotype and poor treatment outcome. The AF5Q31 gene is a fusion partner of the MLL gene involved in the pathogenesis of 11q23-associated ALL. (From LocusLink and OMIM) ( NCI )]
UMLS (NCI) C1332033ALL1 Fused Gene From 5q31
ALL1 Fused Gene From Chromosome 5q31
ALL1 Fused Gene From Chromosome 5q31
- Amino Acid, Peptide, or Protein
- Biologically Active Substance
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