[Encoded by human ADRB1 Gene (GPCR1 Family), 477-aa 51-kDa conserved Beta-1-Adrenergic Receptor is an integral membrane protein receptor for catecholamine epinephrine and norepinephrine neurotransmitters that activates adenylate cyclase through G protein action. ADRB1 phosphorylation by beta-adrenergic receptor kinase mediates receptor desensitization. Agonist and antagonist drugs selective for beta-1 receptors have important applications in clinical medicine. (NCI) ( NCI )]
UMLS (NCI) C0001642 - Amino Acid, Peptide, or Protein
- Receptor
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