[Tumor Necrosis Factor Receptor Binding involves a temporary non-covalent highly specific and high affinity interaction through intermolecular physical forces of attraction and spatial complementarity with a group of cell surface intrinsic membrane proteins (alpha and beta TNF Receptors, NGFR family) that mediate the cytotoxic effects of secreted glycoprotein cytokine TNF signaling molecules through modification of the activity of signal transduction pathways to regulate immune responses to infection. ( NCI )]
UMLS (NCI) C1323363