[This protein is a telomere specific binding protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. (LocusLink) ( NCI )]
UMLS (NCI) C1336702Telomeric-Repeat Binding Factor 2
TERF2
- Amino Acid, Peptide, or Protein
- Biologically Active Substance