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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
T T T, T- T0 T1 T2 T3 T4 T9 TA TB TC TD TE TF TG TH TI TJ TK TL TM TN TO TP TQ TR TS TT TU TV TW TY TZ
TL2 TLC TLI TLK TLL TLR TLT

TLR6

[Expressed in monocytes, CD11c+ immature dendritic cells, and dermal endothelial cells by human TLR6 Gene (TLR Family), 796-aa 92-kDa (precursor) type I membrane protein Toll-Like Receptor 6 contains a TIR domain and 13 LRR repeats. Sharing structural and functional similarities, highly conserved TLRs recognize pathogen-associated molecular patterns expressed on infectious agents and mediate cytokine production necessary for effective immunity. Bound extracellularly to TLR2, TLR6 mediates cellular response to fungi and bacterial lipoproteins MALP-2, STF, PSM, and OspA-L. TLR6 acts via MyD88 (TIR interaction) and TRAF6, leading to NF-kappa-B activation, cytokine secretion, and the inflammatory response. (NCI) ( NCI )]
UMLS (NCI) C0768454
Toll-Like Receptor 6
 
Amino Acid, Peptide, or Protein
Immunologic Factor
Receptor
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