[Encoded by human RFP Gene (TRIM Family), 513-aa 58.5-kDa RET Finger Protein contains a TRIM motif: 3 zinc-binding domains, a RING, a type 1 and type 2 B-box, and a coiled-coil region. Located in the nuclear matrix, RFP interacts with enhancer of polycomb protein, represses gene transcription, and is thought to be involved in male germ cell differentiation. Gene rearrangements with RET produce RET transforming protein, containing the RFP N-terminus with the RET protein tyrosine kinase. (NCI) ( NCI )]
UMLS (NCI) C0084325 - Amino Acid, Peptide, or Protein
- Biologically Active Substance