[While pharmacogenetics largely focuses on candidate genes, such as drug-metabolizing enzymes, pharmacogenomics broadens the scope of study to include all genes (ie, the genome). The latter approach takes into account that a patient's response to any given drug depends on numerous proteins in the body, such as metabolizing enzymes, transporters, receptors, and entire signaling networks mediating the response. Furthermore, genetic defects that underlie the disease process could determine the drug's effects even if they have no direct bearing on its mechanism of action. (from Medscape Pharmacotherapy) ( NCI )]
UMLS (NCI) C1138555 - Biomedical Occupation or Discipline