[Widely expressed by human PLAGL1 Gene (Krueppel Family), 411-aa 45-kDa DNA-binding transcriptional activator Pleomorphic Adenoma-Like Protein 1 contains 7 C2H2-type zinc fingers and inhibits cell proliferation through induction of the p53 apoptosis and cell cycle arrest pathways. PLAGL1 also regulates pituitary adenylate cyclase-activating polypeptide type 1 receptor, a potent insulin secretagogue and mediator of autocrine control of insulin secretion in the pancreatic islets. (NCI) ( NCI )]
UMLS (NCI) C0757769PLAG-Like 1
Pleiomorphic Adenoma-Like Protein 1
Pleomorphic Adenoma Gene-Like 1 Protein
ZAC Tumor Supressor
Zinc Finger Protein PLAGL1
- Amino Acid, Peptide, or Protein
- Biologically Active Substance