[The sodium salt of indomethacin, a methylated indole derivative with anti-inflammatory, analgesic-antipyretic and tocolytic effects. Indomethacin is a non-selective, reversible, and competitive inhibitor of cyclooxygenases 1 and 2, thereby blocking the conversion of arachidonic acid into prostaglandin precursors. Consequently, prostaglandin synthesis is decreased, and prostaglandin-mediated activities are prevented, including pain, inflammation, fever and uterine contraction. ( NCI )]
UMLS (NCI) C0982211INDOMETHACIN SODIUM PREPARATION
- Organic Chemical
- Pharmacologic Substance
Relation/PAR: 1-(4-chlorobenzoyl)-5-methoxy- 2-methyl-1-H-indole-3-acetic acid
[CV900] CARDIOVASCULAR AGENTS, OTHER
Relation/CHD: INDOMETHACIN SODIUM 1 MG