[Human von Willebrand factor, a 270 kD multimeric plasma glycoprotein, has functional binding domains to platelet glycoprotein Ib, glycoprotein Iib/IIIa, collagen and heparin. It mediates platelet adhesion to injured vessel walls and serves as a carrier and stabiliser for coagulation factor VIII. It is expressed in endothelial cells, platelets, megakaryocytes and a number of tumors. (NCI) ( NCI )]
UMLS (NCI) C0015513 - Amino Acid, Peptide, or Protein
- Biologically Active Substance