[DNA TOPOISOMERASES that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. DNA Topoisomerases, Type I enzymes reduce the topological stress in the DNA structure by relaxing the superhelical turns and knotted rings in the DNA helix. ( MSH )]
UMLS (CSP) C0012920 - Amino Acid, Peptide, or Protein
- Enzyme
Relation/PAR: isomerase