[DNA Mismatch Repair Protein PMS1, encoded by the PMS1 gene, is implicated, with MSH2 and MLH1, in mismatch repair of dinucleotide and trinucleotide sequences. A cloned gene for Hereditary Non-Polyposis Colon Cancer, the PMS1 Gene (MUTL/HEXB family) at 2q31-q33 is associated with colon, endometrial, and stomach cancers. Human PMSL genes exhibit homology to bacterial mutL genes and yeast PMS1 gene. (From SWISS-PROT, OMIM, and NCI) ( NCI )]
UMLS (NCI) C0258380 - Amino Acid, Peptide, or Protein
- Biologically Active Substance
home 
Armenian-English 
top