[An aryloxypropanolamine derivative with antihypertensive property. Pindolol competitively binds to beta-adrenergic receptors, resulting in a decrease in beta-adrenergic activities, i.e., vasodilation, and negative chronotropic and inotropic effects. In addition, this agent blocks serotonin (5-HT) 1A receptors, thereby increasing the available serotonin in the brain. Increased serotonin levels augment the antidepressant action of selective serotonin reuptake inhibitors and monoamine oxidase inhibitors. ( NCI )]
UMLS (NCI) C0031937 - Organic Chemical
- Pharmacologic Substance
Relation/PAR: Propanolamines
[CV100] BETA-BLOCKERS/RELATED
Relation/CHD: PINDOLOL 10 MG
PINDOLOL 5 MG