(6R,7R)-7-((R)-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid
[A beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephradine binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. ( NCI )]
UMLS (NCI) C0007738- Organic Chemical
- Antibiotic
Relation/PAR: cephalexin
[AM101] CEPHALOSPORINS, 1ST GENERATION
[AM101] CEPHALOSPORINS, 1ST GENERATION
Relation/CHD: CEPHRADINE 250 MG
CEPHRADINE 500 MG
CEPHRADINE 125 MG/5ML
CEPHRADINE 250 MG/5ML
CEPHRADINE 500 MG
CEPHRADINE 125 MG/5ML
CEPHRADINE 250 MG/5ML
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