(1R,2S)-(1,2-Epoxypropyl)phosphonic Acid, compound with 2-Amino-2-(hydroxymethyl)-1,3-propanediol(1:1)
[The tromethamine salt form of fosfomycin, a synthetic broad-spectrum antibiotic. Fosfomycin tromethamine binds to and inactivates the enzyme enolpyruvyl transferase. This leads to an irreversible blockage of the condensation of uridine diphosphate-N-acetylglucosamine with p-enolpyruvate, which is one of the first steps of bacterial cell wall synthesis, thereby eventually causing cell lysis. In addition, fosfomycin tromethamine reduces the adherence of bacteria to uroepithelial cells. (NCI05) ( NCI )]
UMLS (NCI) C0543454- Organophosphorus Compound
- Antibiotic
Relation/PAR: FOSFOMYCIN
1,3-Propanediol, 2-Amino-2-(hydroxymethyl)-
1,3-Propanediol, 2-Amino-2-(hydroxymethyl)-
Relation/CHD: FOSFOMYCIN TROMETHAMINE 3 GM
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