[A water soluble, amphipathic preparation of d-alpha-tocopherol succinate coupled, through a succinate linker, to polyethylene glycol (PEG) 1000. Due to its amphipathic property, tocophersolan is easily taken up into enterocytes where fat soluble d-alpha-tocopherol is released after hydrolysis. This preparation displays an enhanced absorption of d-alpha tocopherol compared to the administration of free d-alpha-tocopherol. In addition, tocophersolan may also enhance the absorption of water-insoluble agents and other fat-soluble vitamins. This agent has the ability to form its own micelles due to its amphipathic nature, thereby allowing absorption in absence of bile acids. ( NCI )]
UMLS (NCI) C0606070