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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
N N- N0 N3 NA NB NC ND NE NF NG NH NI NK NL NM NN NO NP NR NS NT NU NV NX NY NZ
NA NA+ NA2 NAA NAB NAC NAD NAE NAF NAG NAH NAI NAK NAL NAM NAN NAP NAQ NAR NAS NAT NAU NAV NAX NAZ

NADPH Dependent Diflavin Oxidoreductase 1

[Broadly expressed by human NR1 Gene (FNR Family), 597-aa 67-kDa cytoplasmic NADPH-Dependent FMN and FAD Containing Oxidoreductase is an enzyme homologous to cytochrome P-450 reductase that binds FMN, FAD, and NADPH cofactors, reduces cytochrome c, and metabolizes electron acceptors doxorubicin, menadione, and potassium ferricyanide. NR1 shares 41 to 44% similarity with nitric oxide synthase-2, methionine synthase transferase, and P-450 reductase. It may play a role in metabolic activation of bioreductive anticancer drugs and other chemicals activated by 1-electron reduction. (NCI) ( NCI )]
UMLS (NCI) C1312754
NADPH-Dependent FMN and FAD Containing Oxidoreductase
NDOR1
NR1
 
Amino Acid, Peptide, or Protein
Enzyme

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