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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
M M0 M1 M2 M4 M5 M7 M8 M9 MA MB MC MD ME MF MG MH MI MK ML MM MN MO MP MR MS MT MU MV MY
MA MAA MAB MAC MAD MAE MAF MAG MAH MAI MAJ MAK MAL MAM MAN MAO MAP MAR MAS MAT MAU MAX MAY MAZ

Mannan-Binding Lectin

[A recombinant protein similar or identical to human Mannan-binding lectin (MBL) that plays an important role in the innate immune defence. MBL is a plasma protein containing a carbohydrate recognition domain at one end and a collagen-like stalk domain at the other. The presence of multiple carbohydrate binding sites in a single molecule of MBL allows strong affinity to microorganisms. Upon binding, activation of the complement system leads to the deposition of complement components on the surface of the microorganisms (opsonisation) and to the clearance of the microorganisms by phagocytic cells. Administration of the agent to deficient individuals may restore lectin function in vivo, and thereby be beneficial in management of the immunodeficiency. ( NCI )]
UMLS (NCI) C0065661
 
Amino Acid, Peptide, or Protein
Biologically Active Substance

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