I I- I0 I1 I2 I3 I4 I5 I6 I7 I8 I9 IA IB IC ID IE IF IG IH II IK IL IM IN IO IP IQ IR IS IT IU IV IX
IL IL1 IL2 IL3 IL4 IL5 IL6 IL7 IL8 IL9 ILA ILB ILC ILD ILE ILF ILG ILI ILK ILL ILM ILN ILO ILP ILR ILS ILT ILV ILX ILZ
IL-12 gene
[The DNA sequence that encodes the protein cytokine interleukin-12 (IL-12). When introduced as the complementary DNA (cDNA) form into tumor cells by, for example, a genetically engineered adenovirus vector, the transfected IL-12 cDNA expresses IL-12 which activates antitumoral natural killer (NK) cells and CD8+ T-cells and stimulates the secretion of interferon-gamma (IFN-gamma), potentially inhibiting tumor cell metastasis. This gene therapy may also result in IL-12-mediated inhibition of vascular endothelial growth factor (VEGF) and enhancement of matrix metalloproteinases (MMPs). (NCI04) ( NCI )]
UMLS (NCI) C0879338Interleukin-12 Gene
pIL-12
Plasmid DNA Encoding Human Interleukin-12
Plasmid IL-12
pIL-12
Plasmid DNA Encoding Human Interleukin-12
Plasmid IL-12
- Gene or Genome
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