[A radioimmunoconjugate of a human-murine chimeric IgG2 monoclonal antibody (MoAb) 81C6 labeled with iodine 131 (I-131), with imaging and radioimmunotherapeutic properties. MoAb 81C6 recognizes the extracellular matrix antigen tenascin (hexabrachion), up-regulated in gliomas and other cancers. Using MoAb 81C6 as a carrier for I-131 results in the targeted imaging and/or destruction of cells expressing tenascin. ( NCI )]
UMLS (NCI) C0796329iodine I 131 MOAB 81C6
Iodine I 131 Monoclonal Antibody 81C6
- Amino Acid, Peptide, or Protein
- Pharmacologic Substance
- Immunologic Factor