[A rare, highly malignant, epithelial tumor that develops from a hydatidiform mole (50%), following abortion (25%), or during normal pregnancy (22%). Histologically, choriocarcinomas consist of invasive and anaplastic trophoblastic tissue composed of cytotrophoblastic and syncytiotrophoblastic cells, secretion of human chorionic gonadotropin, and abundant vascularity. Because of rapid growth and a high propensity for hemorrhage, this neoplasm often constitutes a medical emergency. —2004 ( NCI )]
UMLS (NCI) C0349557 
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