[A cancer vaccine containing an epitope of glycosphingolipid GD2 conjugated with the immunostimulant Keyhole Limpet Hemocyanin (KLH), with potential antineoplastic activity. The disialoganglioside GD2 is a tumor associated antigen expressed on the surface of several cancers, including neuroblastoma medulloblastomas, astrocytomas, melanomas, small-cell lung cancer, osteosarcomas and other soft tissue sarcomas. Vaccination with GD2-KLH vaccine may elicit antibody production against cells expressing GD2 ganglioside, thereby reducing tumor cell growth. ( NCI )]
UMLS (NCI) C0338229 - Organic Chemical
- Pharmacologic Substance
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