[Encoded by human FOXO1A Gene (Forkhead Family), ubiquitous 655-aa 70-kDa Forkhead Box O1A is a probable nuclear transcription factor (phosphorylated by AKT1; insulin-induced) that contains 1 forkhead domain and may play a role in myogenic growth and differentiation. Translocations of the FOXO1A gene - t(2;13)(q35;q14) or t(1;13)(p36;q14) - are associated with alveolar rhabdomyosarcoma-2 that produce FOXO1A/PAX3 and FOXO1A/PAX7 transcriptional activators. (NCI) ( NCI )]
UMLS (NCI) C0250455 - Amino Acid, Peptide, or Protein
- Biologically Active Substance
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