[A synthetic organic analogue of inorganic pyrophosphate with antiviral properties. Foscarnet (trisodium phosphonoformate) selectively blocks the pyrophosphate binding site of virus-specific DNA polymerases at concentrations that do not affect cellular DNA polymerases. Because this agent crosses the blood brain barrier, it may be used in the treatment of viral infections of the CNS. (NCI04) ( NCI )]
UMLS (NCI) C0146934 - Organophosphorus Compound
- Pharmacologic Substance