[Endothelin-1, encoded by the EDN1 gene is a potent, 21-amino acid vasoconstrictor peptide produced by vascular endothelial cells. Endothelin-1 inhibits active Na-K transport by inhibiting Na(+)-K(+)-ATPase in intact renaltubular epithelial cells. (From OMIM, PubMed and NCI) ( NCI )]
UMLS (NCI) C0079281 - Amino Acid, Peptide, or Protein
- Biologically Active Substance