[The hydrochloride salt form of mechlorethamine, a synthetic agent related to sulphur mustard with antineoplastic and immunosuppressive properties. Nitrogen mustard (a member of a family of chemotherapy agents including cyclophosphamide and chlorambucil) is an irritant and carcinogenic agent metabolized to a highly reactive ethylene immonium derivative; the ethylene immonium derivative alkylates DNA and inhibits DNA replication. This agent also exhibits lympholytic properties. (NCI04) ( NCI )]
UMLS (NCI) C0600266 - Organic Chemical
- Pharmacologic Substance
- Hazardous or Poisonous Substance
Relation/PAR: Bis(2-chloroethyl)methylamine
Relation/CHD: MECHLORETHAMINE HYDROCHLORIDE 10 MG