[BID (BH3 Interacting domain Death agonist) is a death agonist that heterodimerizes with either agonists (BAX) or antagonists (BCL2). BID is a member of the BCL-2 family of cell death regulators. BID is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves BID, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. (from RefSeq Summary) ( NCI )]
UMLS (NCI) C0531588 - Amino Acid, Peptide, or Protein
- Biologically Active Substance