[Expressed in heart, kidney, liver, skeletal muscle by human SLC25A4 Gene (Mitochondrial Carrier Family), 298-aa 33-kDa homodimeric Adenine Nucleotide Translocator-1 is an integral membrane protein embedded asymmetrically in the inner mitochondrial membrane that catalyzes transmembrane exchange of ADP and ATP and determines the rate of ADP/ATP flux between mitochondrion and cytosol. Strongly similar to murine Ant1, ANT1 contains 3 solute carrier (Solcar) repeats and the signature RRRMMM motif of nucleotide carriers; six alpha helices form a compact transmembrane domain. Defects in SLC25A4 are a cause of PEO. ( NCI )]
UMLS (NCI) C1442881ADP-ATP Translocase-1
ANT
ANT1
Heart-Skeletal Muscle ADP-ATP Carrier Protein-T1
Mitochondrial Adenine Nucleotide Translocator Solute Carrier Family 25 Member-4
Skeletal Muscle Adenine Nucleotide Translocator-1
T1
- Amino Acid, Peptide, or Protein
- Biologically Active Substance