[KU70 protein is the 70 kD subunit of the KU autoantigen, a heterodimeric DNA repair complex that binds DNA double-strand breaks, is the DNA-binding component of the DNA-dependent protein kinase, and facilitates repair by nonhomologous end-joining. KU70 and KU80 form a dyad-symmetrical molecule with a preformed ring that encircles duplex DNA. KU protein is also involved in V(D)J recombination. KU is identical to DNA helicase II, an ATP-dependent DNA unwinding enzyme. (from OMIM 152690 and NCI) ( NCI )]
UMLS (NCI) C1311257G22P1
Ku70 Protein
La Protein
Lupus Autoantigen
Lupus Ku Autoantigen
Thyroid Autoantigen 70kD
- Amino Acid, Peptide, or Protein
- Enzyme