[Expressed in many tissues by human PLCB3 Gene, 1234-aa 139-kDa membrane-bound Phospholipase C Beta 3 contains a catalytic PI-PLC X-box domain, a catalytic PI-PLC Y-box domain, and a C2 domain. Activated in response to stimulation by hormones, growth factors, neurotransmitters, and other ligands, PLCB3 is a key enzyme in initiating receptor-mediated signal transduction by mediating production of DAG and IP3 second messengers. (NCI) ( NCI )]
UMLS (NCI) C1377871Phosphoinositide Phospholipase C
Phospholipase C Beta 3
Phospholipase C Beta 3, Phosphatidylinositol-Specific
PLCB3
PLC-Beta-3
- Amino Acid, Peptide, or Protein
- Enzyme