(11beta)-21-(3-Carboxy-1-oxopropyl)-11,17-dihydroxypregn-4-ene-3,20-dione, Monosodium Salt

[The sodium salt of hydrocortisone succinate with glucocorticoid property. Hydrocortisone sodium succinate is chemically similar to the endogenous hormone that stimulates anti-inflammatory and immunosuppressive activities, in addition to exhibit minor mineralocorticoid effects. This agent binds to intracellular glucocorticoid receptors and is translocated into the nucleus, where it initiates the transcription of glucocorticoid-responsive genes such as various cytokines and lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes, both potent mediators of inflammation. ( NCI )]

UMLS (NCI) C0770560

Cortisol Sodium Succinate
Hydrocortisone 21-Sodium Succinate
Hydrocortisone Na Succinate
Hydrocortisone Sodium Succinate
HYDROCORTISONE SODIUM SUCCINATE PREPARATION
Sodium hydrocortisone succinate

Steroid
Pharmacologic Substance

Relation/PAR: (11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione

Relation/CHD: HYDROCORTISONE SODIUM SUCCINATE 125 MG/ML
HYDROCORTISONE SODIUM SUCCINATE 250 MG
HYDROCORTISONE SODIUM SUCCINATE 50 MG/ML
HYDROCORTISONE SODIUM SUCCINATE 500 MG
HYDROCORTISONE SODIUM SUCCINATE 100 MG
HYDROCORTISONE SODIUM SUCCINATE 1000 MG

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