(+-)-Methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate Hydrochloride
[The hydrochloride salt form of esmolol, a short and rapid-acting beta adrenergic antagonist belonging to the class II anti-arrhythmic drugs and devoid of intrinsic sympathomimetic activity. Esmolol hydrochloride competitively blocks beta1-adrenergic receptors in cardiac muscle and reduces the contractility and cardiac rate of heart muscle, thereby decreasing cardiac output and myocardial oxygen demands. This agent also decreases sympathetic output centrally and blocks renin secretion. At higher doses, esmolol hydrochloride also blocks beta-2 receptors located in bronchial and vascular smooth muscle, thereby leading to smooth muscle relaxation. ( NCI )]
UMLS (NCI) C0700606- Organic Chemical
- Pharmacologic Substance
Relation/PAR: esmolol
Relation/CHD: ESMOLOL HYDROCHLORIDE 10 MG/ML
ESMOLOL HYDROCHLORIDE 250 MG/ML
ESMOLOL HYDROCHLORIDE 250 MG/ML
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